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Second most common infection in the US proving harder to treat with current antibiotics
Date:11/13/2012

Washington, D.C. Certain types of bacteria responsible for causing urinary tract infections (UTIs), the second-most-common infection in the United States, are becoming more difficult to treat with current antibiotics, according to new research from Extending the Cure (ETC), a project of the Center for Disease Dynamics, Economics & Policy. ETC released the research via its online ResistanceMap, an online tool created to track changes in antibiotic drug use and resistance. This year, ResistanceMap features analysis using ETC's Drug Resistance Index, a way for non-experts to track changes in antibiotic effectiveness.

Using an index that tracks antibiotic resistance over time, researchers found that the available arsenal of drugs used to treat UTIs are losing their overall effectiveness, with the overall share of resistant bacteria increasing by over 30% between 1999 and 2010. There are currently about five drug classes used to treat UTIs. The analysis combined the extent of their use with data on their ability to treat organisms that cause urinary infections. This research was funded in part by the Robert Wood Johnson Foundation.

Urinary tract infections are the second most common type of infection, accounting for about 8.6 million visits to health care providers each year, according to the Centers for Disease Control and Prevention. More than half of U.S. women will get a UTI in their lifetime.

"Without proper antibiotic treatment, UTIs can turn into bloodstream infections, which are much more serious and can be life-threatening," said Ramanan Laxminarayan, director of Extending the Cure (ETC). "These findings are especially disturbing because there are few new antibiotics to replace the ones that are becoming less effective. New drug development needs to target the types of drug-resistant bacteria that cause these infections," he said.

In addition to their overall findings about UTI drug resistance, researchers found wo
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Contact: Dionne Dougall-Bass
dionne@burnesscommunications.com
301-961-5803
Burness Communications
Source:Eurekalert

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