Navigation Links
Second-generation drug used for hypertension aids heart function independent of blood pressure
Date:4/22/2012

ing the effect of the central nervous system (CNS) receptors to decrease sympathetic activation and thus reduce blood pressure. In the study, salt-sensitive, hypertensive rats either received Moxonidine or were assigned to the control group. Researchers later found that the animals who received the drug had a marked inhibition of the sympathetic activity (an area of the brain) compared to those that did not. The findings suggest that inhibition of the central sympathetic outflow is important in the mechanism of hypertension. According to Dr. Hirooka, "The findings are important because they suggest that moxonidine may be useful in targeting the central receptors in the brain that are known to occur in patients with hypertension."

Next Steps

The study is the latest in a series conducted by the research team whose focus is on neural control of circulation in hypertension and heart failure. Looking ahead, they will work to identify the precise mechanisms involved in the beneficial effect of moxonidine, Dr. Hirooka said. They will also study other ways to see if the compound is a possible therapeutic tool for hypertensive heart disease to prevent heart failure. As the drug had beneficial effects on insulin resistance, they would like to further investigate the issue, he added.

Maxonidine is available in select countries in Europe and Asia. It is not currently available in the United States.


'/>"/>

Contact: Donna Krupa
media@faseb.org
619-525-6213
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. De La Rue Provides Second-Generation ePassport for Malta
2. Second-generation device more effective in capturing circulating tumor cells
3. Hypertension disparity linked to environment
4. Severe gestational hypertension may protect against testicular cancer
5. Hypertension develops early, silently, in African-American men
6. Hypertension and cholesterol medications present in water released into the St. Lawrence River
7. Researchers may have found why women have an edge on salt-sensitive hypertension
8. LSUSHC researchers find potential new target for hypertension treatment
9. Common gene variants increase risk of hypertension, may lead to new therapies
10. Pulmonary hypertension in children may result from reduced activity of gene regulator
11. Hypertension among lower-status employees lingers well into retirement
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... that has the entire country in its grip is affecting ... be responsible for the proliferation of a heat-loving amoeba commonly ... hot springs, which the drought has made warmer than usual ... an infection caused by this parasite after swimming in several ... of an individual and travels to the brain. Nose plugs ...
(Date:7/23/2014)... The planet,s soil releases about 60 billion tons of ... more than that released by burning fossil fuels. This ... release of carbon is balanced by carbon coming into ... matter, as well as by the underground activities of ... that rising temperatures increase the rate of soil respiration. ...
(Date:7/23/2014)... Non-biting blow fly Chrysomya megacephala is commonly ... investigations to determine the time of death, referred to ... derived form of C. megacephala from Tamil ... morphological features and molecular characterization through generation of DNA ... in the open access Biodiversity Data Journal . ...
Breaking Biology News(10 mins):Diseases of another kind 2Climate change and the soil 2Dead body feeding larvae useful in forensic investigations 2
... mushroom (Agaricus bisporus) has as much, and in some cases, ... button mushroom is the foremost cultivated edible mushroom in the ... is often thought of as a poor relation to its ... nutritionally. But according to new research in SCIs Journal ...
... Fan Meng of China, a visionary leader who ... in Chinas rapidly industrializing Guangdong Province, has been awarded ... use the Fellowship to expand and improve the regions ... from the serious threats of industrial pollution and unsustainable ...
... to distinguish between the majority of plant species on Earth ... the Proceedings of the National Academy of Sciences journal today ... used to identify plants using a small sample, could lead ... in species-rich areas like rainforests. It could also lead to ...
Cached Biology News:2008 Pew Fellowship in Marine Conservation awarded to Fan Meng; first Chinese fellow 22008 Pew Fellowship in Marine Conservation awarded to Fan Meng; first Chinese fellow 3DNA 'barcode' identified for plants 2DNA 'barcode' identified for plants 3
(Date:7/23/2014)... a2z Inc. announces that AACC will ... Pathfinder, in its 2014 Annual Meeting & Clinical ... planned for July 29-31, 2014 in Chicago, IL at ... connect with global leaders in clinical chemistry, molecular diagnostics, ... of breaking science in laboratory medicine. , ChirpE Photo ...
(Date:7/22/2014)... July 22, 2014 The Board of Directors of ... has declared a quarterly dividend of 54.5 cents per common ... on September 9, 2014. The indicated annual dividend rate is ... BD is a leading medical technology company that partners with ... pressing and evolving health needs. Our innovative solutions are focused ...
(Date:7/22/2014)... in mechanical engineering at the University of Texas at ... the North Texas section of the American Society of ... members in 158 countries who develop engineering standards and ... community, benefiting the world. , ASME recognized Baughn earlier ... honors banquet. Baughn retired as an engineering fellow in ...
(Date:7/22/2014)... Dallas, Texas (PRWEB) July 22, 2014 ... the growth and maintenance of cell culture. They allow ... meet the needs of researchers in drug discovery and ... extensively used in mAb production, iPSC research, cryobanking, cell-based ... and reduce contamination risk. , Analysts forecast the ...
Breaking Biology Technology:AACC Enhances Attendee Experience at Its 2014 Annual Meeting & Clinical Lab Expo with a2z-Powered ChirpE Photo Booth and Mobile App 2AACC Enhances Attendee Experience at Its 2014 Annual Meeting & Clinical Lab Expo with a2z-Powered ChirpE Photo Booth and Mobile App 3UT Dallas professor receives Engineer of the Year award 2Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 2Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 3Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 4
... VALENCIA, Calif., Nov. 20 MannKind,Corporation (Nasdaq: MNKD ... and cancer, announced today that it,will present at the ... AM ET at the Pierre Hotel in New York, ... the live web cast of the,presentation in the Investor ...
... Nov. 20 Sports and,nutritional product manufacturer, Natural ... announced today that it has,launched an international marketing ... Relief Cream. Made from a combination of,botanical and ... the internet and television. Natural Nutrition,s BLUE ...
... Nov. 20 /Xinhua-PRNewswire-FirstCall/ -- 3SBio Inc.,(Nasdaq: SSRX ... developing, manufacturing and marketing biopharmaceutical,products, announces today that ... the 19th Annual Piper Jaffray Health Care Conference ... November 27, 2007 at 4:30 P.M. EST. ...
Cached Biology Technology:Natural Nutrition Launches International Marketing Campaign for New All Natural Analgesic: BLUE LIGHTNING(TM) Fast Pain Relief 2
NEWBORN CALF SERUM AND PLASMA...
Synaptic Vesicle I Sampler Kit 10g each...
Hybridization chamblers suitable for use with all ChIP-GLAS microarrays....
Rabbit polyclonal to BCA1 ( Abpromise for all tested applications). Antigen: Generated using E.coli expressed mouse BCA1. Entrez GeneID: 10563 SWISS Protein ID: O43927...
Biology Products: