Navigation Links
Searching genomic data faster
Date:7/10/2012

CAMBRIDGE, Mass. -- In 2001, the Human Genome Project and Celera Genomics announced that after 10 years of work at a cost of some $400 million, they had completed a draft sequence of the human genome. Today, sequencing a human genome is something that a single researcher can do in a couple of weeks for less than $10,000.

Since 2002, the rate at which genomes can be sequenced has been doubling every four months or so, whereas computing power doubles only every 18 months. Without the advent of new analytic tools, biologists' ability to generate genomic data will soon outstrip their ability to do anything useful with it.

In the latest issue of Nature Biotechnology, MIT and Harvard University researchers describe a new algorithm that drastically reduces the time it takes to find a particular gene sequence in a database of genomes. Moreover, the more genomes it's searching, the greater the speedup it affords, so its advantages will only compound as more data is generated.

In some sense, this is a data-compression algorithm like the one that allows computer users to compress data files into smaller zip files. "You have all this data, and clearly, if you want to store it, what people would naturally do is compress it," says Bonnie Berger, a professor of applied math and computer science at MIT and senior author on the paper. "The problem is that eventually you have to look at it, so you have to decompress it to look at it. But our insight is that if you compress the data in the right way, then you can do your analysis directly on the compressed data. And that increases the speed while maintaining the accuracy of the analyses."

Exploiting redundancy

The researchers' compression scheme exploits the fact that evolution is stingy with good designs. There's a great deal of overlap in the genomes of closely related species, and some overlap even in the genomes of distantly related species: That's why experiments pe
'/>"/>

Contact: Caroline McCall, MIT Media Relations
cmccall5@mit.edu
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Searching for the origin of muscles
2. EU project: Searching for exotics in the shrimp nets
3. The genomics symposium to boost the further development of cancer research
4. ACRG and BGI report findings from genomics research on recurrent hepatitis B virus integration
5. Researchers announce GenomeSpace environment to connect genomic tools
6. 2012 ACMG Foundation/Signature Genomic Laboratories Travel Award winner announced
7. In search for a vaccine, IU biologist receives $2.3 million to explore chlamydia genomics
8. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
9. SDSCs big data expertise aiding genomics research
10. Palladium-gold nanoparticles clean TCE a billion times faster than iron filings
11. Exome sequencing gives cheaper, faster diagnosis in heterogeneous disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2015)... Feb. 24, 2015 Research and Markets ... of the "Global 2D Gesture Recognition Market ... The analysts forecast the Global 2D Gesture ... 32.12% over the period 2014-2019 The ... sectors is one of the major trends in ...
(Date:2/12/2015)... MINNETONKA, Minn. , Feb. 12, 2015 /PRNewswire/ ... technology company specializing in clinical study management systems, ... Partner Program , further distinguishing iMedNet ... for Clinical Research Organizations (CROs) and healthcare consultants.  ... sales support, prospective customer referrals and numerous co-marketing ...
(Date:2/5/2015)... PARK, North Carolina , 5. Februar ... 35. Jahr als spezialisiertes Logistikunternehmen und hat ... als einzige klinische Logistikfirma (Clinical Logistics Organization ... Kernbotschaft der neuen Kampagne lautet First ... Lieferungen. Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
Breaking Biology News(10 mins):Global 2D Gesture Recognition Market 2015-2019 with Cognitec Systems, CogniVue, eyeSight Mobile Technologies & PointGrab Dominating 2MedNet Solutions Announces Key Enhancements To Its iMedNet Partner Program 2Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3
... BOSTON The eon-spanning clock of evolution the ... traits belies a constant ferment in the chambers and ... subtle ripple effects throughout an organism. In a study ... at Dana-Farber Cancer Institute,s Center for Cancer Systems Biology and ...
... Physicians at University Hospitals (UH) Rainbow Babies and Children,s ... the national research consortium AsthmaNet. UH Rainbow, one ... has partnered with University of Pittsburgh Medical Center (through ... on these studies and future asthma clinical research studies ...
... most influential researchers, whose pioneering work in chemical analysis ... top chemists, is set to receive two major, highly ... O. Lawton Professor of Chemistry and Biochemistry at Florida ... at the National High Magnetic Field Laboratory, will receive ...
Cached Biology News:1st large-scale map of a plant's protein network addresses evolution, disease process 21st large-scale map of a plant's protein network addresses evolution, disease process 31st large-scale map of a plant's protein network addresses evolution, disease process 4UH Rainbow Babies and Children's Hospital opens asthma studies 2UH Rainbow Babies and Children's Hospital opens asthma studies 3Acclaimed chemistry professor wins 2 major awards 2Acclaimed chemistry professor wins 2 major awards 3
(Date:2/27/2015)... Markets ( http://www.researchandmarkets.com/research/p2ddnr/global_market ) has announced the addition ... to their offering. , Global Market Report ... Trypsin globally and regionally ( Europe , ... Latin America etc.). It captures Trypsin ... report focuses on three primary areas; manufacture methods & technology ...
(Date:2/27/2015)... 27, 2015 FamilyFarms Group is pleased ... of State Line Farms, received the 2015 Tomorrow’s Top ... under the age of 35, who has demonstrated excellence ... honor to win the Tomorrow's Top Producer Horizon Award. ... the Top Producer Award and learning from their experiences. ...
(Date:2/26/2015)... 26, 2015 On behalf of biotech client ... Wilentz, Goldman & Spitzer, P.A. (Wilentz) secured a ... Genewiz Inc. in excess of $10 million. The jury ... secrets, and that it improperly hired one or more ... motions for judgment notwithstanding the verdict, a new trial, ...
(Date:2/26/2015)... 26, 2015 Protiviti ( www.protiviti.com ), a ... the Governance Portal , designed to increase the ... (GRC) tasks across multiple business units and projects. The ... customers better align their controls with the COSO ( ... requirements. In response to client feedback, Protiviti has also ...
Breaking Biology Technology:Global Market Report of Trypsin 2014-2018 2Matt Sims Receives the 2015 Tomorrow’s Top Producer Horizon Award 2Wilentz Client GenScript Awarded $10 Million in Trade Secrets Case Against Genewiz 2Wilentz Client GenScript Awarded $10 Million in Trade Secrets Case Against Genewiz 3Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 3
... Oct. 24 Cardiogenesis,Corporation (OTC: CGCP), announced that ... ended September 30, 2007 prior to market open ... that President Richard,P. Lanigan and Senior Vice President ... an investor conference call that day at 12:00 ...
... - Continued Strong Organic Growth, With Revenue Up 8.5% Like-for-Like Essilor International, the world ... Consolidated revenue for the first nine months, EUR millions ... % change Like-for-like ... months) ...
... in German . , Hydrogen fuel cells will ... far suffered from being insufficiently competitive. At the University of ... now developed a new class of electrocatalyst that could help ... of the catalyst consists of nanoparticles with a platinum-rich shell ...
Cached Biology Technology:Cardiogenesis Corporation to Report Third Quarter 2007 Results on November 14th 2Essilor's 2007 Third-Quarter Report 2Essilor's 2007 Third-Quarter Report 3Essilor's 2007 Third-Quarter Report 4Platinum-rich shell, platinum-poor core 2
...
... E F L P E P Q H ... L E(19) PA1-072 detects munc-18 interacting protein 3 ... in Western blot procedures. By Western blot, ... Mint3 from AtT20 cell extract.,PA1-072 immunizing peptide corresponds ...
... (AR) Competitor Assay Kits provide a sensitive ... potential AR ligands using fluorescence polarization (FP). ... domain protein tagged with His and GST ... androgen ligand (Fluormone AL Green in the ...
... for complex protein processing and production challenges. We ... you develop a solution to your problem and then ... do additional work/scale-up processes ... transfer all methodology to your own lab , ...
Biology Products: