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Search for the 'on' switches may reveal genetic role in development and disease
Date:1/24/2008

id Terrence Furey, Ph.D., a researcher in the IGSP and co-senior investigator on this study. Identifying these sites may help us understand the biological basis for gene regulation expression patterns in different cell types. We'll also compare patterns within and across species, in response to external stimuli and in diseased tissues.

The researchers said they looked at normal cells for this study because in order to understand anything about disease or the aging processes, it's important to first understand what a normal cell looks like.

Perhaps in the future, this data resource could help researchers learn to turn a harmful gene off or increase the expression of helpful ones, Furey said.


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Contact: Lauren Shaftel Williams
lauren.shaftel@duke.edu
919-684-4966
Duke University Medical Center
Source:Eurekalert

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