Navigation Links
Scripps scientists develop first examples of RNA that replicates itself indefinitely
Date:1/9/2009

lso were capable of sustained replication, with the most fit replicators growing in number to dominate the mixture. "To me that's actually the biggest result," says Joyce.

The research shows that the system can sustain molecular information, a form of heritability, and give rise to variations of itself in a way akin to Darwinian evolution. So, says Lincoln, "What we have is non-living, but we've been able to show that it has some life-like properties, and that was extremely interesting."

Knocking on the Door of Life

The group is pursuing potential applications of their discovery in the field of molecular diagnostics, but that work is tied to a research paper currently in review, so the researchers can't yet discuss it.

But the main value of the work, according to Joyce, is at the basic research level. "What we've found could be relevant to how life begins, at that key moment when Darwinian evolution starts." He is quick to point out that, while the self-replicating RNA enzyme systems share certain characteristics of life, they are not themselves a form of life.

The historical origin of life can never be recreated precisely, so without a reliable time machine, one must instead address the related question of whether life could ever be created in a laboratory. This could, of course, shed light on what the beginning of life might have looked like, at least in outline. "We're not trying to play back the tape," says Lincoln of their work, "but it might tell us how you go about starting the process of understanding the emergence of life in the lab."

Joyce says that only when a system is developed in the lab that has the capability of evolving novel functions on its own can it be properly called life. "We're knocking on that door," he says, "But of course we haven't achieved that."

The subunits in the enzymes the team constructed each contain many nucleotides, so they are relatively complex and not so
'/>"/>

Contact: Keith McKeown
kmckeown@scripps.edu
858-784-8134
Scripps Research Institute
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Scripps Research scientists shed light on how DNA is unwound so that its code can be read
2. Dolphin population stunted by fishing activities, Scripps/NOAA study finds
3. Scripps research team defines new painkilling chemical pathway
4. Scripps research scientists identify blood component that turns bacteria virulent
5. Scripps research scientists identify compounds for stem-cell production from adult cells
6. Scripps Florida scientists awarded $1.5M to fight major water and food parasites
7. Scripps research team sheds light on immune system suppression
8. Scripps research team solves structure of beneficial virus
9. Oceans on the precipice: Scripps scientist warns of mass extinctions and rise of slime
10. Scripps scientists will assess Beijing Olympics air pollution control efforts
11. Scripps study sets high economic value on threatened Mexican mangroves
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research ... announced the addition of the "Global Facial ... http://photos.prnewswire.com/prnh/20130307/600769 ... the identification of individuals. Facial recognition system measures ... as nose, jaw edges, mouth, and the distance ...
(Date:12/11/2014)... ST. PAUL, Minn. , Dec. 10, 2014 ... in wireless physiologic monitoring, has released a new ... changing needs of preclinical toxicology researchers. M series, ... to help toxicologists collect the best possible physiologic ... studies. Adding functional endpoints to toxicology ...
(Date:12/10/2014)... CIE San Diego has launched an innovative ... tissue that enhances care coordination among social service and ... information; earned a second $1 million grant from the ... aging in community and; will be recognized as a ... 4-6p. CIE San Diego today announced ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... some of North Africa,s major droughts of centuries past, ... the year 1179. The first multi-century drought reconstruction ... severe droughts during the 13th and 16th centuries and ... An international research team figured out northwest Africa,s climate ...
... Spanish . A new model for manipulating vitamin ... Service (ARS) scientists who say it could help establish just how ... optimal growth and health. Newborn dairy calves get crucial vitamin ... the first few days after birth. Later, the neonatal calf ...
... 25, 2010An insightful and in-depth presentation of the most ... pediatric interstitial lung disease (ILD) is presented in a ... Pediatric Allergy, Immunology, and Pulmonology (PED), a peer-reviewed ... ). The entire issue is available free online. ( ...
Cached Biology News:20th century one of driest in 9 centuries for northwest Africa 220th century one of driest in 9 centuries for northwest Africa 3Model developed for manipulating vitamin D levels in calves 2Comprehensive overview of Children's Interstitial Lung Disease (chILD) in special issue of Pediatric Allergy, Immunology, and Pulmonology 2
(Date:12/24/2014)... report expects global cell isolation and expansion market to ... carefully analyzed data about the vital drivers, restraints, trends, ... Copy of Report @ http://bit.ly/1yUxy0T , According ... will keep witnessing growth at an impressive CAGR during ... by rapid technological advancements, government funding and investments, and ...
(Date:12/24/2014)... -- PharmaBoardroom,s new report, , Healthcare ... for free download , digs deep into this vibrant ... the sector today. One area where ... developing a homegrown pharmaceutical manufacturing base, even if the government,s ... way off. A cursory comparison with neighboring Morocco ...
(Date:12/22/2014)... PA & Brussels (PRWEB) December 22, 2014 ... (CfPIE), the global leader of technical training across ... Society for Clinical Data Management (SCDM) to provide ... and certification programs —providing access to the more ... partnership extends SCDM members with 10% off when registering ...
(Date:12/22/2014)... GenomeDx Biosciences today announced that a new ... genomic test for prostate cancer, was able to predict ... radical prostatectomy without adjuvant therapy. Although rapid metastasis in ... tumor genomics to identify these men who have a ... advance. The study has been published online by ...
Breaking Biology Technology:The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3
... Aug. 30 Pressure,BioSciences, Inc. (Nasdaq: ... has been,issued its first patent by the ... Biomolecular Complexes" (Number,2,259,318), this issuance extends the ... patents previously issued in the United States,Japan, ...
... SOUTH SAN FRANCISCO, Calif., Aug. 30 VaxGen,Inc. ... filed with the,Securities and Exchange Commission (SEC) its ... December 31, 2006 and Quarterly Reports on Form ... reports can be found at the link titled,"SEC ...
... of the FDA,s,Cooperative Research and Development Agreement (CRADA) ... (FDA) on August 23, 2007, in a,presentation focusing ... at,the Third Annual Regulatory and Compliance Symposium -- ... was held at Harvard University. Helen Winkle, ...
Cached Biology Technology:Pressure BioSciences, Inc. Issued First Patent in Canada 2Pressure BioSciences, Inc. Issued First Patent in Canada 3VaxGen Files 2006 Financial Statements and Provides Cash Update 2FDA and Conformia Deliver Joint Presentation to Annual Regulatory and Compliance Symposium at Harvard 2FDA and Conformia Deliver Joint Presentation to Annual Regulatory and Compliance Symposium at Harvard 3
... These handy dispensers save space ... hats, and other garb. They are ... small parts used in labs, processing ... static charges and the particles they ...
... Double staining is a technique used ... single tissue.(1-6) PicTure™-Double Staining Kit is a ... detecting two antigens simultaneously in the same ... sensitivity. The antigens can be identified using ...
... NOVOstar is an exciting product for cell-based ... assays required the use of expensive HTS ... scientists in the assay development stage. The ... cell-based assays as well as any other ...
... the DH-2000, but comes with a shutter (controlled ... 5 Hz) The DH-2000 Deuterium ... of deuterium and tungsten halogen light sources in ... produces a powerful, stable output from 215-200 nm. ...
Biology Products: