Navigation Links
Scripps research team wins $5.1 million to develop DNA sequencing technology
Date:9/16/2010

LA JOLLA, CA September 16, 2010 For Immediate Release Scripps Research Institute Professor Reza Ghadiri, Ph.D., has been awarded a four-year, $5.1 million grant as part of a National Institutes of Health (NIH) initiative to spur the development of the next generation of DNA sequencing technologies, which could enable biomedical researchers and health care workers to routinely sequence a person's DNA.

With the new grant, funded by the NIH's Human Genome Research Institute (NHGRI), the team will further develop an approach they call "nanopore strand sequencing."

In nanopore strand sequencing, a single strand of DNA moves through a narrow pore and the bases are identified as they pass a reading head. Ghadiri notes that this is a rapid real-time technology; it does not require the time-consuming cyclic addition of reagents.

"After implementing a chip with a million pores, we expect nanopore sequencing to achieve a 15-minute genome by 2014 with a very short sample preparation time," said Ghadiri, whose group will work with the laboratories of Hagan Bayley of the University of Oxford and Amit Meller of Boston University on the project. "In addition, nanopore sequencing will be able to identify modified bases and to sequence RNA directly."

The new grant is part of an $18 million round of funding announced this week by the NHGRI, whose current goal is to make it possible to sequence a genome for $1,000 or less.

Over the past decade, DNA sequencing costs have fallen dramatically fueled in large part by tools, technologies and process improvements developed as part of the successful effort to sequence the human genome. NHGRI subsequently launched programs in 2004 to accelerate the development of sequencing technologies and the rate of reduction of genome sequencing cost. Last year, the program surpassed the goal of producing high quality genome sequence of 3 billion base pairs the amount of DNA found in humans and other mammals for $100,000. The cost to sequence a human genome has now dipped below $40,000.

The new grants will fund ten investigator teams to develop revolutionary technologies that would make it possible to quickly and cost-efficiently sequence a genome, enabling the use of sequencing as part of routine medical care.


'/>"/>

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Source:Eurekalert

Related biology news :

1. Team led by Scripps Research scientist identifies new gene for memory
2. Seafood stewardship questionable: UBC-Scripps experts
3. UCI-Scripps study links cellular motors to memory
4. Scripps Research scientists uncover new mechanism of memory formation
5. Scripps Oceanography biologists awarded prestigious honors
6. Scripps Research scientists uncover possible cocaine addiction trigger
7. Scripps research study opens the door to new class of drugs for epileptic seizures
8. Scripps research study shows infectious prions can arise spontaneously in normal brain tissue
9. Scripps Research scientists find new way to attack cancerous cells
10. Scripps research scientists determine structure of immune molecule that counteracts HIV strains
11. Scripps Research scientists break barrier to creating potential therapeutic molecules
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/2/2016)... 2, 2016  BioMEMS devices deployed in ... on medical screening and diagnostic applications, such ... devices that facilitate and assure continuous monitoring ... are being bolstered through new opportunities offered ... acquisition coupled with wireless connectivity and low ...
(Date:2/2/2016)... Feb. 2, 2016  Based on its recent ... Sullivan recognizes US-based Intelligent Retinal Imaging Systems (IRIS) ... Award for New Product Innovation. IRIS, a prominent ... North America , is poised to set ... diabetic retinopathy market. The IRIS technology presents superior ...
(Date:1/27/2016)... Jan. 27, 2016  Rite Track, Inc. a leading ... West Chester, Ohio announced today the ... staff, based in Austin, Texas , ... to provide modifications, installations and technical support offerings for ... of PLUS, commented, "PLUS has provided world class service ...
Breaking Biology News(10 mins):
(Date:2/9/2016)... ... February 09, 2016 , ... Clinovo , the cloud-based ... Electronic Data Capture (EDC) system ClinCaptureand its new Contract Research Organization (CRO) Partner ... Conference in San Mateo, California on February 10th and 11th. Watch 2-min ...
(Date:2/9/2016)... 9, 2016  DNAtrix, a clinical stage, ... announced that its lead product, DNX-2401, has ... an orphan medicinal product for the treatment ... glioma, strikes approximately 25,000 people a year ... http://photos.prnewswire.com/prnh/20160208/330986LOGO --> http://photos.prnewswire.com/prnh/20160208/330986LOGO ...
(Date:2/9/2016)... 9, 2016 DelveInsight,s, ... report provides in depth insights on the ... the Protein-Tyrosine Phosphatase 1B (PTP1B) Inhibitors. The ... various stages of development including Discovery, Pre-clinical, ... and Preregistration. Report covers the product clinical ...
(Date:2/8/2016)... 8, 2016 Novan, Inc. today announced that Director ... of Directors of Novan. In addition, Robert Keegan has ... North Carolina . --> North Carolina ... it received a total of $32.8 million of net proceeds in ... investor network originating throughout the Research Triangle area of ...
Breaking Biology Technology: