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Scripps awarded $7.9 million NIH grant for research to find root cause of heart attack
Date:7/1/2011

me is radically different from a person's genome. And people's genomes are radically different from one another. In our research we'll be working internally on each person's genome to understand what's going on, which is unique and very exciting."

Scripps' NIH grant application included a proof-of-concept experiment in which scientists achieved transformation of Dr. Topol's blood cells into induced pluripotent stem cells. Dr. Topol, who carries the 9p21 risk variant, is poised to be the first person ever to have his own heart-artery lining cells created and genomically edited. "The idea of being able to see what my cells look like, both with and without my 9p21 risk locus, is like science fiction," Dr. Topol said.

This study is an extension of Scripps' leadership in heart care and research. Scripps recently broke ground on the $456 million Scripps Cardiovascular Institute (SCI), a center for innovation that will bring together top researchers, physicians and staff. SCI will incorporate leading-edge wireless technologies and individualized medicine for the best in patient care when it opens in 2015. Annually, more than 55,000 patients receive their cardiovascular care from Scripps, making it San Diego County's largest heart care provider. Scripps is the region's only cardiovascular program consistently recognized by U.S. News & World Report as one of the best in the country.


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Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Source:Eurekalert  

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Scripps awarded $7.9 million NIH grant for research to find root cause of heart attack
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