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Scripps and Complete Genomics to collaborate on genetic research study on healthy aging
Date:10/3/2011

MOUNTAIN VIEW and LA JOLLA, Calif. Oct. 3, 2011 Complete Genomics Inc. (NASDAQ: GNOM), the whole human genome sequencing company, and the not-for-profit Scripps Health system today announced a major collaboration that will help further the Wellderly Study, a landmark scientific research initiative aimed at unlocking the genetic secrets of lifelong health.

Under the collaboration, Complete Genomics will sequence, at its own cost, the whole human genomes of 1,000 participants in the Wellderly Study. The Wellderly Study is headed by Scripps Health Chief Academic Officer Dr. Eric J. Topol, who has spent the past four years recruiting healthy elderly individuals who are at least 80 years old and free from major diseases and long-term medications. The median age of this study group is 87, and participants range up to 108 years old.

"There have been a significant number of longevity studies, but the Wellderly Study is the first one focused specifically on healthy aging," said Dr. Topol. "Furthermore, through our partnership with Complete Genomics, we are now conducting the largest whole genome study of a single phenotype healthy lifespan or healthspan. We anticipate that by employing Complete Genomics' sequencing service, and being able to study participants' entire genome for the first time, we will gain valuable insights into the genetic variants that have helped protect the health of our Wellderly population."

The purpose of the Wellderly Study is twofold. First, it is to uncover the genetic underpinnings of healthy life span, which likely involve guardian genes that protect against chronic diseases. Second, healthy older individuals are ideal controls for genetic studies of late-onset diseases such as various cancers, heart disease, Alzheimer's disease and Parkinson's disease.

In addition to sequencing the whole genomes of these 1,000 Wellderly Study participants, Complete Genomics will work with Scripps to assemble the re
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Contact: Steve Carpowich
carpowich.stephen@scrippshealth.org
858-678-7183
Scripps Health
Source:Eurekalert

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