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Scripps Research scientists win $65 million in new grants to reveal form and function of proteins
Date:9/30/2010

LA JOLLA, CA September 30, 2010 For Immediate Release Scripps Research Institute scientists have been awarded approximately $65 million in four five-year grants as part of the National Institutes of Health's (NIH) latest round of structural biology funding. The projects will focus on determining the shapes and functions of proteins and protein complexes that are important in biology and medicine.

"The grants are an acknowledgement of The Scripps Research Institute's leadership in the field of structural studies," said Scripps Research President Richard A. Lerner, M.D. "We're looking forward to many more important advances from our scientists thanks to this latest round of support from the NIH."

The four Scripps Research grants are part of the NIH Protein Structure Initiative (PSI), an effort that started in 2000 with the main goal of developing highly efficient methods for solving the structures of many different proteins. The new grants mark the beginning of the effort's third phase, called "PSI:Biology." A key aim of this phase is to apply the high-throughput methods developed during the initiative's first decade to challenging biological problems and systems.

"These awards to Scripps Research represent the key elements of the Protein Structure Initiativefrom generating structures and new structure determination methods for particularly challenging proteins to harnessing the power of high-throughput to address important biological problems," said Ward Smith, Ph.D., director of the PSI. "Together, these approaches can significantly advance our understanding of the role proteins play in health and disease."

The Scripps Research grants are:

  • $37.6 million to a consortium led by Ian A. Wilson, D.Phil., Hansen Professor of Structural Biology and member of the Skaggs Institute for Chemical Biology at Scripps Research.
  • $5.8 million to a group led by Jamie Williamson, Ph.D., professor, dean of the graduate
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Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Source:Eurekalert

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