Navigation Links
Scripps Research Institute study shows how brain cells shape temperature preferences
Date:1/29/2013

JUPITER, FL, January 29, 2013 While the wooly musk ox may like it cold, fruit flies definitely do not. They like it hot, or at least warm. In fact, their preferred optimum temperature is very similar to that of humans76 degrees F.

Scientists have known that a type of brain cell circuit helps regulate a variety of innate and learned behavior in animals, including their temperature preferences. What has been a mystery is whether or not this behavior stems from a specific set of neurons (brain cells) or overlapping sets.

Now, a new study from The Scripps Research Institute (TSRI) shows that a complex set of overlapping neuronal circuits works in concert to drive temperature preferences in the fruit fly Drosophila by affecting a single target, a heavy bundle of neurons within the fly brain known as the mushroom body. These nerve bundles, which get their name from their bulbous shape, play critical roles in learning and memory.

The study, published in the January 30, 2013 edition of the Journal of Neuroscience, shows that dopaminergic circuitsbrain cells that synthesize dopamine, a common neurotransmitterwithin the mushroom body do not encode a single signal, but rather perform a more complex computation of environmental conditions.

"We found that dopamine neurons process multiple inputs to generate multiple outputsthe same set of nerves process sensory information and reward-avoidance learning," said TSRI Assistant Professor Seth Tomchik. "This discovery helps lay the groundwork to better understand how information is processed in the brain. A similar set of neurons is involved in behavior preferences in humansfrom basic rewards to more complex learning and memory."

Using imaging techniques that allow scientists to visualize neuron activity in real time, the study illuminated the response of dopaminergic neurons to changes in temperature. The behavioral roles were then examined by silencing various subsets of th
'/>"/>

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Scripps Florida scientists uncover potential drug target to block cell death in Parkinsons disease
2. Scripps physicians call for change in cancer tissue handling
3. $1 million Kenan Trust Grant extends support of Scripps Florida education outreach
4. Scripps Research Institute scientists describe elusive replication machinery of flu viruses
5. Scripps Research Institute team identifies a potential cause of Parkinsons disease
6. Scripps Florida scientists design molecule that reverses some fragile X syndrome defects
7. Scripps Research Institute scientists show copper facilitates prion disease
8. Scripps Research scientists show potent new compound virtually eliminates HIV in cell culture
9. Scripps Research Institute wins $77 million to develop AIDS vaccine center
10. Scripps Florida scientists identify critical quality control for cell growth
11. Scripps Research Institute Scientists Develop Alternative to Gene Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scripps Research Institute study shows how brain cells shape temperature preferences
(Date:12/22/2014)... Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce ... security consultant, Apollo Robbins for the 2015 ... Apollo Robbins will be ... , 2015, demonstrating some of his famous theft techniques ...
(Date:12/22/2014)... 2014  The 2014 Holiday Season may be ... Acuity Market Intelligence reports that the long anticipated ... Acuity forecasts that intensifying demand for smart phones, ... will drive a global market of 2.5 billion ... 2020.   According to Maxine ...
(Date:12/19/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ... Market Monitor: North America Perimeter Security Systems Market" ... http://photos.prnewswire.com/prnh/20130307/600769 The North American perimeter security ... 3.6% from 2014 to 2019. Although the U.S. market ... Canada is expected to grow at a ...
Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3
... A new paper published online in Nature ... type of lung cancer may one day benefit from targeted ... Squamous cell lung cancer kills more people each ... to lung adenocarcinoma in the number of deaths it causes. ...
... extensive forest death triggered by hot and dry climatic ... Forest mortality due to drought and heat stress is ... has focused on isolated incidents of forest mortality, little ... die-offs. A new analysis of the current literature on ...
... applied fertilizer to newly placed sod may result in nutrient ... best time to apply fertilizer and what kind is the ... is a team of scientists from Texas A&M AgriLife Research: ... management; Dr. Ben Wherley, assistant professor of turfgrass science and ...
Cached Biology News:New potential targets discovered for treating squamous cell lung cancers 2New potential targets discovered for treating squamous cell lung cancers 3Forest mortality and climate change: The big picture 2Forest mortality and climate change: The big picture 3Turf study to monitor runoff, establish fertilizer management practices 2
(Date:12/24/2014)... AUSTIN, Texas , Dec. 23, 2014 /PRNewswire/ ... solutions company focused on gynecologic disease, announced today ... W. Schuler , Birchview Fund LLC and several ... million of unregistered shares of Vermillion,s common stock ... common stock in a private placement.  ...
(Date:12/24/2014)... 2014  Rock Creek Pharmaceuticals, Inc., (NASDAQ: ... Clinical Trial Application (CTA) with the United ... seeking regulatory approval to initiate clinical trials for the ... Contingent on the Company receiving CTA regulatory approval, ... to assess the safety, tolerability and dose escalation of ...
(Date:12/22/2014)... 2014   Synthetic Biologics, Inc. ... therapies for serious infections and diseases, with ... announced positive topline safety and tolerability results ... SYN-004, the Company,s investigational oral beta-lactamase enzyme ... (C. difficile) infection, antibiotic-associated diarrhea and ...
(Date:12/22/2014)... 2014 GenomeDx Biosciences today announced that a ... a genomic test for prostate cancer, was able to ... by radical prostatectomy without adjuvant therapy. Although rapid metastasis ... using tumor genomics to identify these men who have ... important advance. The study has been published online ...
Breaking Biology Technology:Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3
... Markets Inc. (OTCQX: PINK), the financial information and ... quotation and trading system in the U.S. OTC ... (OTCQX: CRMMF, TSX.V: CRM), a Canadian-based medical technology ... highest tier, OTCQX®. (Logo:   http://photos.prnewswire.com/prnh/20090708/NY43125LOGO ...
... DIEGO, Aug. 17 MabVax Therapeutics, Inc., a privately ... of vaccine and antibody based therapies to address the ... it has received a Small Business Innovation Research Grant ... agency,s Streamlined Non-competing Award Procedures (SNAP). Under the SNAP ...
... of only two studies of its kind, a study from ... School of Graduate Biomedical Sciences at Tufts demonstrates that non-viral ... eye disease and preserve vision. The team developed nanoparticles to ... mice temporarily retained more eyesight than controls. The study, published ...
Cached Biology Technology:CRH Medical Corp. Joins OTCQX 2CRH Medical Corp. Joins OTCQX 3MabVax Therapeutics Receives Small Business Innovation Research Program Award from the National Cancer Institute 2MabVax Therapeutics Receives Small Business Innovation Research Program Award from the National Cancer Institute 3Breakthrough gene therapy prevents retinal degeneration 2
Anti-Mouse Qa.m8, Ascites (Clone 5035-24.1) (mouse IgG3)...
... contains 4 deuterium atoms at the 9, 10, ... use as an internal standard for the quantification ... is produced by incubation of linoleic acid with ... to inhibit the adhesion of tumor cells to ...
... Mass Standards Kit includes reagents that can ... instrument parameters, and calibrate the mass scale ... designed for use with the 4700 Proteomics ... Standards in the kit require minimal preparation ...
...
Biology Products: