Navigation Links
Scripps Research Institute study shows how brain cells shape temperature preferences
Date:1/29/2013

JUPITER, FL, January 29, 2013 While the wooly musk ox may like it cold, fruit flies definitely do not. They like it hot, or at least warm. In fact, their preferred optimum temperature is very similar to that of humans76 degrees F.

Scientists have known that a type of brain cell circuit helps regulate a variety of innate and learned behavior in animals, including their temperature preferences. What has been a mystery is whether or not this behavior stems from a specific set of neurons (brain cells) or overlapping sets.

Now, a new study from The Scripps Research Institute (TSRI) shows that a complex set of overlapping neuronal circuits works in concert to drive temperature preferences in the fruit fly Drosophila by affecting a single target, a heavy bundle of neurons within the fly brain known as the mushroom body. These nerve bundles, which get their name from their bulbous shape, play critical roles in learning and memory.

The study, published in the January 30, 2013 edition of the Journal of Neuroscience, shows that dopaminergic circuitsbrain cells that synthesize dopamine, a common neurotransmitterwithin the mushroom body do not encode a single signal, but rather perform a more complex computation of environmental conditions.

"We found that dopamine neurons process multiple inputs to generate multiple outputsthe same set of nerves process sensory information and reward-avoidance learning," said TSRI Assistant Professor Seth Tomchik. "This discovery helps lay the groundwork to better understand how information is processed in the brain. A similar set of neurons is involved in behavior preferences in humansfrom basic rewards to more complex learning and memory."

Using imaging techniques that allow scientists to visualize neuron activity in real time, the study illuminated the response of dopaminergic neurons to changes in temperature. The behavioral roles were then examined by silencing various subsets of th
'/>"/>

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Scripps Florida scientists uncover potential drug target to block cell death in Parkinsons disease
2. Scripps physicians call for change in cancer tissue handling
3. $1 million Kenan Trust Grant extends support of Scripps Florida education outreach
4. Scripps Research Institute scientists describe elusive replication machinery of flu viruses
5. Scripps Research Institute team identifies a potential cause of Parkinsons disease
6. Scripps Florida scientists design molecule that reverses some fragile X syndrome defects
7. Scripps Research Institute scientists show copper facilitates prion disease
8. Scripps Research scientists show potent new compound virtually eliminates HIV in cell culture
9. Scripps Research Institute wins $77 million to develop AIDS vaccine center
10. Scripps Florida scientists identify critical quality control for cell growth
11. Scripps Research Institute Scientists Develop Alternative to Gene Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scripps Research Institute study shows how brain cells shape temperature preferences
(Date:8/20/2014)... salty aroma of sunscreen and seawater signals a relaxing ... that the idyllic beach vacation comes with an environmental ... into the sea, they can become toxic to some ... course for many other marine animals. Their study appears ... . , Antonio Tovar-Sanchez and David Snchez-Quiles point out ...
(Date:8/20/2014)... gene therapy developed by researchers at the University of ... mice from a life-threatening heart condition caused by muscular ... said Yi Lai, Ph.D., the leading author of the ... of Medicine,s Department of Molecular Microbiology and Immunology. "This ... could lead to a treatment for people with this ...
(Date:8/20/2014)... , Aug. 20, 2014  The second annual ... in Tampa, Florida on ... with Steven Rahman, Director, Technology and Strategy at Samsung, ... Experian. The theme of this year,s event is ... "Biometrics UnPlugged: Mobility at the ...
Breaking Biology News(10 mins):Gene therapy protects mice from lethal heart condition, MU researchers find 2Biometrics UnPlugged: Mobility at the Crossroads of Commerce & Privacy to Feature Interactive Sessions with Samsung and Experian 2
... soil samples indicates that a group of microorganisms called ... oxidize ammonia, according to an international team of researchers ... , Soil microbes, in a process ... nitrates, which are used as nutrients by plants. , ...
... the sequencing of the chimpanzee genome last year, geneticists have ... our closest evolutionary relative, looking for the differences that distinguish ... the human DNA sequence with the most dramatically increased rate ... is still unknown, but it appears to be directly involved ...
... estimates, hepatitis has become a worldwide health problem, ... abroad. Researchers are experimenting with combinations of ... In research presented today at Digestive Disease ... making significant progress to improve symptoms of the ...
Cached Biology News:Ammonia-loving archaea win landslide majority 2Ammonia-loving archaea win landslide majority 3Researchers identify human DNA on the fast track 2Researchers identify human DNA on the fast track 3Novel therapy combinations gain ground in treating hepatitis 2Novel therapy combinations gain ground in treating hepatitis 3Novel therapy combinations gain ground in treating hepatitis 4Novel therapy combinations gain ground in treating hepatitis 5Novel therapy combinations gain ground in treating hepatitis 6
(Date:8/21/2014)... 2014 Pursuit Solutions ( http://www.pursuit-solutions.com ... and services for Life Sciences sales and marketing ... of New Commercial Sales Models” by Peter Robinson, ... The article examines some innovative models used to ... tested in the pharmaceutical market. Robinson grades the ...
(Date:8/20/2014)... , Aug. 20, 2014 Clintrax ... services located in Raleigh, NC ... Evans as Vice President of Administration. ... will oversee all corporate processes, including their alignment ... Clintrax Global, Brad worked as an HR executive, ...
(Date:8/20/2014)... Livermore, California (PRWEB) August 20, 2014 ... to develop and apply the most complete climate ... challenging and demanding climate change issues. , Eight ... combining forces with the National Center for Atmospheric ... in the new effort. Other participating national laboratories ...
(Date:8/20/2014)... JOSE, Calif. , Aug. 20, 2014 /PRNewswire-iReach/ ... highlights the transformative collaboration between the school,s bioengineering ... As part of the Intel® Software Academic Program, ... computer sciences and the human body.  ... The study exhibits the work of Dr. ...
Breaking Biology Technology:Pursuit's Peter Robinson Publishes "Grading Pharma's Use of New Commercial Sales Models" 2Clintrax Global, Inc. Announces Addition to Executive Team 2New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3Intel and University of San Diego Bioengineering Department Release Case Study on Health Sciences Research 2
... Madison Wis - The University of Wisconsin Medical ... integration of the Medical Foundation's clinical data and to ... The foundation has choosen QDX Platform V Integration ... vertical solutions company based in Englewood, Colorado. , ,The ...
... an ATM and point-of-sale (POS) processing business, said ... increase more than 57% in 2003 to 223 million ... was tremendous and makes ACCEL/Exchange one of the nation's ... President of Products and Networks for Fiserv EFT/CNS. "In ...
... Madison, Wis. -- OpGen, Inc. , a provider of ... optical mapping study of a deadly type of brain tumor, ... the Hermelin Brain Tumor Center and professor of ... founder of OpGen, David Schwartz . , ,Optical mapping, ...
Cached Biology Technology:UW Medical Foundation Integrates Medical Records 2OpGen joins UW, Henry Ford Heath in Improving Brain Tumor Treatment 2
Rabbit polyclonal to NCoR2, prediluted ( Abpromise for all tested applications). entrezGeneID: 9612 SwissProtID: Q9Y618...
...
... Anti-Clusterin α chain (human), clone 41D ... Immunogen : Native clusterin purified ... pH 7.4, 0.15M NaCl and 0.05% ... on RIPA lysates from HeLa cells ...
Anti-CoralHue Dronpa Green Monoclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Biology Products: