Navigation Links
Scott & White Healthcare researcher finds success with new anti-cancer drug
Date:12/22/2009

A study conducted at Scott & White Healthcare in Temple, Texas, found that a new drug stopped the growth of breast tumors in mice. This drug is unique in that it works both by stopping the cancer cells from growing and metastasizing to other organs, and by stimulating the immune system to destroy breast cancer cells and keeps them from coming back. This is the only drug that's able to work in both ways, while all other treatments work in one way or another. And, this research initiative not only involves physicians and biologists working together to bring treatments from the laboratory to the bedside, but a unique third component agriculturalists.

Researcher Alexzander Asea, Ph.D., the Effie and Wofford Cain Endowed Chair in Clinical Pathology, and division chief of investigative pathology at Scott & White Healthcare and the Texas A&M Health Science Center, said "we found that some of the mice were essentially cured."

"All anti-cancer drugs broadly fall into two categories; either directly killing cancer cells (often healthy cells as well), or vaccines that help sick patients by boosting the immune system to better fight off cancer. This new drug works both ways, as a vaccine by taking away the cancer cell ability to grow, multiply and spread to distant organs, and by educating the immune system to recognize the breast cancer cells as 'foreign invaders' that need to be attacked and destroyed and to continue that process over time," Dr. Asea said.

Dr. Asea went on to say "breast cancer cells fly under the radar of the immune system, by turning off the machinery that normally puts recognition structures on the surface of cancer cells which the immune system uses to recognize and destroy them. To overcome this problem, this injectable drug turns on this machinery within the cancer cells allowing the immune system to recognize the cancer cells and kill them. The unique thing is that the revved-up immune cells will continue patrolling for any hidden cancer cells months and years after the last cancer cells have been killed," Dr. Asea said.

"Collaborating with the agricultural community on this research also allows us to use a special delivery mechanism of the drug that doesn't cause the negative side effects you see with more traditional treatments like chemotherapeutic agents," explained Dr. Asea.

Dr. Asea said only about one year of additional work is required before Phase I clinical trials can begin in women with metastatic breast cancer at Scott & White Hospital. "However, this stage requires a significant amount of funding. We're currently looking at various sources including federal, state and private sources to get this promising drug to the patients who need it."


'/>"/>

Contact: Katherine Voss
kvoss@swmail.sw.org
254-724-4097
Scott & White Healthcare
Source:Eurekalert

Related biology news :

1. Wolf reintroduction proposed in Scottish Highland test case
2. TGen Clinical Research Services at Scottsdale Healthcare and Mayo Clinic study new cancer drug
3. Phoenix conference highlights TGens and Scottsdale Healthcares contributions to molecular oncology
4. TGen, Scottsdale Healthcare, Mayo Clinic study new drug to stimulate immune system of cancer victims
5. American Society for Microbiology honors D. Scott Merrell
6. JDRF announces diabetes research program with Johnson & Johnson
7. Increased Spending on the EUs External Borders to Drive the Border Security Market, Says Frost & Sullivan
8. Frost & Sullivan Recognises Sagem Securite for its Innovative Automated Border Control Systems
9. Johnson & Johnson award goes to research of the cause of brain cell damage in Parkinsons
10. Texas A&M Researchers Examine How Viruses Destroy Bacteria
11. Innovative R&D prioritization tool earns Baxter the 2009 INFORMS Decision Analysis Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/15/2017)... 15 2017   ivWatch LLC , a medical device company ... today announced receipt of its ISO 13485 Certification, the global standard ... Organization for Standardization (ISO®). ... Model 400 Continuous Monitoring device for the early detection of IV ... "This is an important milestone for ...
(Date:7/20/2017)... 2017 Delta (NYSE: DAL ) customers now can ... at Reagan Washington National Airport (DCA). ... Delta launches biometrics to board aircraft at Reagan ... Delta,s biometric boarding pass experience that ... now integrated into the boarding process to allow eligible Delta SkyMiles Members ...
(Date:6/30/2017)... , June 30, 2017 Today, American ... and supplier of face and eye tracking software, ... Product provider program. "Artificial intelligence ... way to monitor a driver,s attentiveness levels while ... being able to detect fatigue and prevent potential ...
Breaking Biology News(10 mins):
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... ... Lithography Equipment for the Semiconductor, MEMS, and Microfluidics Industries, announces the new Model ... specifications found more often in automated production mask aligners. OAI has already received ...
(Date:8/16/2017)... of Prussia, PA (PRWEB) , ... August 16, 2017 , ... ... will be taking part in sessions at the ISPE Annual Meeting and Expo ... Marriott Marquis San Diego Marina. The event’s theme is “Driving innovation to advance patient ...
(Date:8/16/2017)... ... August 16, 2017 , ... While art and science are often ... connected than one might think. A Mesh Is Also a Snare, a group ... City Science Center’s Esther Klein Gallery (EKG) on August 17 and run through September ...
(Date:8/16/2017)... , Aug. 16, 2017  This year,s edition of the Inc. 5000 ... life sciences workforce solutions, has made the list for the third year ... the nation,s fastest-growing private companies based on a set of quantitative metrics. ... includes the fastest-growing companies in the Bay State . ... Inc. 5000 ...
Breaking Biology Technology: