Navigation Links
Scorpion venom -- bad for bugs, good for pesticides
Date:4/27/2011

EAST LANSING, Mich. -- Fables have long cast scorpions as bad-natured killers of hapless turtles that naively agree to ferry them across rivers. Michigan State University scientists, however, see them in a different light.

Ke Dong, MSU insect toxicologist and neurobiologist, studied the effects of scorpion venom with the hopes of finding new ways to protect plants from bugs. The results, which are published in the current issue of the Journal of Biological Chemistry, have revealed new ways in which the venom works.

Past research identified scorpion toxin's usefulness in the development of insecticides. Its venom attacks various channels and receptors that control their prey's nervous and muscular systems. One major target of scorpion toxins is the voltage-gated sodium channel, a protein found in nerve and muscle cells used for rapid electrical signaling.

"Interestingly, some scorpion toxins selectively affect one type of sodium channels, but not others," Dong said. "The goal of our scorpion toxin project is to understand why certain scorpion toxins act on insect sodium channels, but not their mammalian counterparts."

Dong and a team of researchers were able to identify amino acid residues in insect sodium channels that make the channels more vulnerable to the venom from the Israeli desert scorpion. The team also discovered that an important sodium channel voltage sensor can influence the potency of the scorpion toxin.

"Investigating the venom's effect on the voltage-gated sodium channel could provide valuable information for designing new insecticides that work by selectively targeting insect sodium channels," Dong said.

Several classes of insecticides act on sodium channels, but insects become resistant to them over time. The researchers are studying how insects develop resistance and what alternatives can be created to control resistant pests, Dong added.


'/>"/>

Contact: Layne Cameron
layne.cameron@ur.msu.edu
517-353-8819
Michigan State University
Source:Eurekalert

Page: 1

Related biology news :

1. Pterygotid sea scorpions: No longer terror of the ancient seas?
2. Deathstalker scorpion venom could improve gene therapy for brain cancer
3. Scorpion venom provides clues to cause, treatment of pancreatitis
4. Phylogenetic analysis of Mexican cave scorpions suggests adaptation to caves is reversable
5. A deadly scorpion provides a safe pesticide
6. Scorpion biodiversity
7. Microscopic morphology adds to the scorpion family tree
8. Cone of poison: The secret behind the cone snails venom pump
9. Novel bee venom derivative forms a nanoparticle smart bomb to target cancer cells
10. Tarantula venom-based MD therapy to be advanced by UB scientists biotech company
11. Killer catfish? Venomous species surprisingly common, study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2016)... PROVO and SANDY, ... Screening Ontario (NSO), which operates the highest sample volume ... testing, and Tute Genomics and UNIConnect, leaders in clinical ... today announced the launch of a project to establish ... testing panel. NSO has been contracted ...
(Date:3/15/2016)... JERUSALEM , March 15, 2016 ... Jerusalem , the technology-transfer company of the Hebrew University, ... developer of remote sensing technology of various human biological ... funding, raising $2.0 million from private investors. ... technology, based on the detection of electromagnetic emissions from ...
(Date:3/10/2016)... 2016 --> ... "Identity and Access Management Market by Component (Provisioning, Directory ... by Organization Size, by Deployment, by Vertical, and by ... The market is estimated to grow from USD 7.20 ... at a Compound Annual Growth Rate (CAGR) of 12.2% ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... Melbourne, FL (PRWEB) , ... May 25, 2016 , ... ... of eight she tore her cruciate ligament in her left knee. Lady’s owner Hannah ... , a central Florida board-certified veterinary surgeon, to repair her cruciate ligament and help ...
(Date:5/24/2016)... ... 24, 2016 , ... Cell therapies for a range of ... research at Worcester Polytechnic Institute (WPI) that yielded a newly patented method of ... The novel method, developed by WPI faculty members Raymond Page, PhD, professor of ...
(Date:5/24/2016)... Jolla, CA (PRWEB) , ... May 24, 2016 , ... ... financial planning for corporate executives and entrepreneurs, held The Future of San Diego Life ... in the San Diego life science community attended the event with speakers Dr. Rich ...
(Date:5/23/2016)... ... ... for blood donations in South Texas and across the nation is growing. , But according ... donations are on the decline. In fact, donations across the country are at their lowest ... in the last four years alone. , There is no substitute for blood. , “We ...
Breaking Biology Technology: