Navigation Links
Scorpion venom -- bad for bugs, good for pesticides
Date:4/27/2011

EAST LANSING, Mich. -- Fables have long cast scorpions as bad-natured killers of hapless turtles that naively agree to ferry them across rivers. Michigan State University scientists, however, see them in a different light.

Ke Dong, MSU insect toxicologist and neurobiologist, studied the effects of scorpion venom with the hopes of finding new ways to protect plants from bugs. The results, which are published in the current issue of the Journal of Biological Chemistry, have revealed new ways in which the venom works.

Past research identified scorpion toxin's usefulness in the development of insecticides. Its venom attacks various channels and receptors that control their prey's nervous and muscular systems. One major target of scorpion toxins is the voltage-gated sodium channel, a protein found in nerve and muscle cells used for rapid electrical signaling.

"Interestingly, some scorpion toxins selectively affect one type of sodium channels, but not others," Dong said. "The goal of our scorpion toxin project is to understand why certain scorpion toxins act on insect sodium channels, but not their mammalian counterparts."

Dong and a team of researchers were able to identify amino acid residues in insect sodium channels that make the channels more vulnerable to the venom from the Israeli desert scorpion. The team also discovered that an important sodium channel voltage sensor can influence the potency of the scorpion toxin.

"Investigating the venom's effect on the voltage-gated sodium channel could provide valuable information for designing new insecticides that work by selectively targeting insect sodium channels," Dong said.

Several classes of insecticides act on sodium channels, but insects become resistant to them over time. The researchers are studying how insects develop resistance and what alternatives can be created to control resistant pests, Dong added.


'/>"/>

Contact: Layne Cameron
layne.cameron@ur.msu.edu
517-353-8819
Michigan State University
Source:Eurekalert

Page: 1

Related biology news :

1. Pterygotid sea scorpions: No longer terror of the ancient seas?
2. Deathstalker scorpion venom could improve gene therapy for brain cancer
3. Scorpion venom provides clues to cause, treatment of pancreatitis
4. Phylogenetic analysis of Mexican cave scorpions suggests adaptation to caves is reversable
5. A deadly scorpion provides a safe pesticide
6. Scorpion biodiversity
7. Microscopic morphology adds to the scorpion family tree
8. Cone of poison: The secret behind the cone snails venom pump
9. Novel bee venom derivative forms a nanoparticle smart bomb to target cancer cells
10. Tarantula venom-based MD therapy to be advanced by UB scientists biotech company
11. Killer catfish? Venomous species surprisingly common, study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... Feb. 9, 2016 Aware, Inc. (NASDAQ: AWRE ), ... results for its fourth quarter and year ended December 31, 2015.  ... the fourth quarter of 2015 was $6.9 million, an increase of ... Operating income in the fourth quarter of 2015 was $2.6 million ... --> --> Higher revenue and ...
(Date:2/8/2016)... , February 8, 2016 ... platform which presents innovation for clients, comfort and ... called VoiceKey. --> Worldcore is ... innovation for clients, comfort and unbeatable security, with ... --> Worldcore is the first ...
(Date:2/4/2016)... , Feb. 4, 2016 The field ... one of the most popular hubs of the ... and other huge studies of human microbiota, have ... few years, the microbiome space has literally exploded ... research. This report focuses on biomedical aspects ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... Calif. , Feb. 11, 2016  Dovetail Genomics™ ... to its beta program for a planned metagenomic genome ... present the company,s metagenomic genome assembly method in a ... in Genome Biology & Technology conference in ... of these highly complex datasets is difficult. Using its ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... stem cell treatment clinic in Quito, Ecuador. The new facility will provide advanced ... to patients from around the world. , The new GSCG clinic is ...
(Date:2/10/2016)... 2016 ASAE is introducing a hybrid membership ... (AMC) the option of joining or renewing through an ... by staff size, every employee in any size association ... reap all available member benefits.   John ... membership options will allow organizations of any size and ...
(Date:2/10/2016)... Austin, Texas (PRWEB) , ... February 10, 2016 ... ... research centers across three states, announced today the promotion of two long-standing principal ... and Chief of Family Medicine, Clinical Research and Development. , Dr. Laurence Chu, ...
Breaking Biology Technology: