Navigation Links
Scorpion venom -- bad for bugs, good for pesticides
Date:4/27/2011

EAST LANSING, Mich. -- Fables have long cast scorpions as bad-natured killers of hapless turtles that naively agree to ferry them across rivers. Michigan State University scientists, however, see them in a different light.

Ke Dong, MSU insect toxicologist and neurobiologist, studied the effects of scorpion venom with the hopes of finding new ways to protect plants from bugs. The results, which are published in the current issue of the Journal of Biological Chemistry, have revealed new ways in which the venom works.

Past research identified scorpion toxin's usefulness in the development of insecticides. Its venom attacks various channels and receptors that control their prey's nervous and muscular systems. One major target of scorpion toxins is the voltage-gated sodium channel, a protein found in nerve and muscle cells used for rapid electrical signaling.

"Interestingly, some scorpion toxins selectively affect one type of sodium channels, but not others," Dong said. "The goal of our scorpion toxin project is to understand why certain scorpion toxins act on insect sodium channels, but not their mammalian counterparts."

Dong and a team of researchers were able to identify amino acid residues in insect sodium channels that make the channels more vulnerable to the venom from the Israeli desert scorpion. The team also discovered that an important sodium channel voltage sensor can influence the potency of the scorpion toxin.

"Investigating the venom's effect on the voltage-gated sodium channel could provide valuable information for designing new insecticides that work by selectively targeting insect sodium channels," Dong said.

Several classes of insecticides act on sodium channels, but insects become resistant to them over time. The researchers are studying how insects develop resistance and what alternatives can be created to control resistant pests, Dong added.


'/>"/>

Contact: Layne Cameron
layne.cameron@ur.msu.edu
517-353-8819
Michigan State University
Source:Eurekalert

Page: 1

Related biology news :

1. Pterygotid sea scorpions: No longer terror of the ancient seas?
2. Deathstalker scorpion venom could improve gene therapy for brain cancer
3. Scorpion venom provides clues to cause, treatment of pancreatitis
4. Phylogenetic analysis of Mexican cave scorpions suggests adaptation to caves is reversable
5. A deadly scorpion provides a safe pesticide
6. Scorpion biodiversity
7. Microscopic morphology adds to the scorpion family tree
8. Cone of poison: The secret behind the cone snails venom pump
9. Novel bee venom derivative forms a nanoparticle smart bomb to target cancer cells
10. Tarantula venom-based MD therapy to be advanced by UB scientists biotech company
11. Killer catfish? Venomous species surprisingly common, study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... , April 11, 2017 Crossmatch®, ... secure authentication solutions, today announced that it has ... Advanced Research Projects Activity (IARPA) to develop next-generation ... program. "Innovation has been a driving ... Thor program will allow us to innovate and ...
(Date:4/6/2017)... 6, 2017 Forecasts by Product ... Readers, by End-Use (Transportation & Logistics, Government & Public ... & Fossil Generation Facility, Nuclear Power), Industrial, Retail, Business ... Are you looking for a definitive report on ... ...
(Date:4/4/2017)... NEW YORK , April 4, 2017   ... solutions, today announced that the United States Patent and ... The patent broadly covers the linking of an iris ... the same transaction) and represents the company,s 45 th ... our latest patent is very timely given the multi-modal ...
Breaking Biology News(10 mins):
(Date:5/19/2017)... ... May 19, 2017 , ... ... Program. Academic researchers with technologies ripe for commercialization, and who are affiliated ... Delaware, are encouraged to submit proposals. QED, now in its tenth round, is ...
(Date:5/18/2017)... ... ... Supplies Management (“CSM”), a Great Point Partners II (“GPP”) portfolio company, today announced two ... size over the past six months with the acquisition of businesses in Belgium and ... Chief Financial Officer. Roger has over 25 years of experience in finance and ...
(Date:5/18/2017)... ... 2017 , ... Cognition Corporation ( http://www.cognition.us ), ... version 9.0 of the Cognition Cockpit platform. , “Our whole team has put ... CEO of Cognition. “We’re thrilled to finally be able to release it to ...
(Date:5/18/2017)... College Station, TX (PRWEB) , ... May 17, ... ... cleanroom design and construction, announced today that their Chief Executive Officer, Maik Jornitz, ... Power List. The UK publication’s Power List celebrates 100 individuals “involved in bettering ...
Breaking Biology Technology: