Navigation Links
Scientists watch as peptides control crystal growth with 'switches, throttles and brakes'
Date:11/23/2009

single-molecule resolution, is normally difficult to do without knocking the molecules off," said Raymond Friddle, an LLNL postdoctoral fellow. But the team improved upon previous methods and achieved unprecedented resolution of the molecular structure of the crystal surface during the dynamic interaction of each growing layer with peptides. "We were able to watch peptides adhere to the surface, temporarily slow down a layer of the growing crystal, and surprisingly 'hop' to the next level of the crystal surface."

The images also revealed a mechanism that molecules can use to bind to surfaces that would normally repel them. The high resolution images showed that peptides will cluster together on crystal faces that present the same electronic charge. Under certain conditions the peptides would slow down growth, while under other conditions the peptides could speed up growth.

On another face of the crystal, where the peptides were expected to bind strongly, the researchers found instead that the peptides did not attach to the surface unless the crystal growth slowed. The peptides needed to bind in a specific way to the face, which takes more time than a non-specific attachment. As a result, the growing layers of the crystal were able to shed off the peptides as they attempted to bind.

But when the researchers slowed down the crystal growth rate, the peptides collapsed onto the surface so strongly that they completely stopped growth. The researchers proposed that the phenomenon is due to the unique properties of bio-polymers, such as peptides or polyelectrolytes, which fluctuate in solution before resting in a stable configuration on a surface.

"The results of the catastrophic drop in growth by peptides suggest ways that organisms achieve protection against pathological mineralization," said Jim De Yoreo, the project lead and deputy director of research at LBNL's Molecular Foundry. "Once growth is halted, a very high concentration of
'/>"/>

Contact: Anne Stark
stark8@llnl.gov
925-422-9799
DOE/Lawrence Livermore National Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Reference genome of maize, most important US crop, is published by team co-led by CSHL scientists
2. ORNL, Los Alamos pioneer new approach to assist scientists, farmers
3. Scripps research scientists find new link between insulin and core body temperature
4. Smithsonian scientists find the frog legs trade may facilitate spread of pathogens
5. Scientists unravel evolution of highly toxic box jellyfish
6. Members of Congress, university leaders, scientists launch ScienceWorksForUS
7. Scientists guide immune cells with light and microparticles
8. Scientists put interactive flu tracking at publics fingertips
9. Singapore scientists join international study of 10,000 vertebrates genomes
10. Scientists are first to unlock the mystery of creating cultured pearls from the queen conch
11. UM scientists create fruit fly model to help unravel genetics of human diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... DETROIT , Jan. 13, 2015 Technology Showcase, Hall ... iris-based identity authentication solutions, today announced it will showcase its ... and developed by the Department of Energy,s Oak Ridge ... International Auto Show . EyeLock,s iris identity authentication technology is ...
(Date:1/22/2015)... (NASDAQ: NXTD and NXTDW) a biometric authentication company focused ... the Wocket™ smart wallet at CES 2015 in Las Vegas ... of the "11 Hot Products at CES" in a review published in ... by Newseveryday.com and "The top 10 gadgets from CES 2015" by ...
(Date:1/22/2015)... MUNICH , January 22, 2015 ... its tenth year  The European Patent Office to present ... Two British nominations to be featured: Christofer Toumazou ... week featuring former finalists and winners of the Award   ...
Breaking Biology News(10 mins):EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3
... -- In research published in the Jan. 17 issue of ... by Susana Gonzalo, Ph.D., assistant professor of biochemistry and molecular ... that contributes to triple-negative breast cancer, an often deadly and ... women. In addition, Gonzalo and her team identified vitamin D ...
... hands with antibacterial soap, most don,t think about where ... of Minnesota engineering researchers do. A new University ... called triclosan, used in soaps and many other products ... lakes. The findings are directly linked to increased triclosan ...
... Biologist Erica Larschan, Ph.D., was ... Month," for her innovative findings on chromosomal activity in fruit flies. ... at Brown University in identifying a protein that allows a male ... That advantage, if proven similar in human males, could point the ...
Cached Biology News:Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say 2Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say 3Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say 4Antibacterial agent used in common soaps found in increasing amounts in freshwater lakes 2Antibacterial agent used in common soaps found in increasing amounts in freshwater lakes 3
(Date:1/22/2015)... , Jan. 22, 2015  Derma Sciences, Inc. (Nasdaq: ... focused on advanced wound care, announces that AMNIOEXCEL® ... have been added to the Premier, Inc. Regenerative ... opportunity for the AMNIOEXCEL® and AMNIOMATRIX® product lines, ...
(Date:12/24/2014)... and NEW YORK , Dec. 24, 2014 ... advancing patient care in critical areas, announced the closing of ... and warrants to purchase up to an aggregate 3,500,000 shares ... share and $.01 per warrant.  The warrants have a per ...
(Date:12/24/2014)... 23, 2014 “Preparative & Process ... Flash), Consumables (Columns, Solvents, Buffers, Valves, Guages, Seals), ... Agriculture) - Forecasts to 2019” provides a detailed ... current market trends, and strategies impacting the preparative ...
(Date:12/24/2014)... SoundConnect’s 2015 next ... edge communication technology, provide continued education and inform ... series demonstrates online communication features and benefits; empowering ... most innovative and powerful tools. , According to ...
Breaking Biology Technology:Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3
... (DNA Diagnostics Center), the largest provider of private DNA paternity ... international attendees for a tour and behind the scenes look ... p.m. at DDC, One DDC Way, Fairfield, Ohio. ... International Exploration of Wrongful Conviction held in Cincinnati, Ohio, April ...
... diesel Capillary action and graphite foam are being ... a logistical nightmare for the military and U.S. troops deployed ... water a day, just getting that water to them increases ... proprietary system, however, this problem could be greatly reduced. The ...
... ALCLS), the genome engineering specialist, has announced today that its ... Depots (a French financial institution) for a planned capital investment ... to Cellectis and Caisse des Depots. This agreement ... subject to the achievement of certain technical conditions. ...
Cached Biology Technology:DDC to Name DNA Analyzer "Hello Truth" During Innocence Project International Delegate Tour 2Story tips from the Department of Energy's Oak Ridge National Laboratory: April 2011 2Story tips from the Department of Energy's Oak Ridge National Laboratory: April 2011 3Story tips from the Department of Energy's Oak Ridge National Laboratory: April 2011 4Cellectis and Caisse des Depots Sign Agreement on a Project for the Industrial Development of iPS Cells 2Cellectis and Caisse des Depots Sign Agreement on a Project for the Industrial Development of iPS Cells 3
Mouse polyclonal antibody to NR2F2 - nuclear receptor subfamily 2, group F, member 2...
Mouse polyclonal antibody raised against a partial recombinant MHC2TA. NCBI Entrez Gene ID = 4261...
... Smart Minis 300V power supply (Cat. No. ... voltage, sufficient for SDS-PAGE, and native PAGE ... pairs of terminator pairs can be used ... for individuals to have his/her own power ...
... NightOWL is a dedicated imaging system for ... Equipped with a very sensitive camera to ... plants in tumor research, infectious disease research, ... blots. NightOWL is the only imager with ...
Biology Products: