Navigation Links
Scientists use computer algorithms to develop seasonal flu vaccines
Date:7/9/2010

ithms indicate the best places in the genome to make the changes, such that the new synthetic genome encodes exactly the same proteins as the wild-type genome, but in lesser quantities.

This process allows a wide margin of safety, explains Papamichail. "The probability of all the changes reverting themselves to produce a virulent strain is extremely unlikely," he says.

Although the new sequence and the original sequence both direct the synthesis of exactly the same proteins, the new sequence gives a weakened version of the virus; for that reason the live vaccine is capable of eliciting an immune reaction against the wild-type virus, but is not strong enough to cause disease symptoms. This method used to weaken the influenza virus is a general one, and may allow the creation of safe, effective vaccines against many different types of viruses.

In the future, the researchers would like to explore the applicability of their techniques, with the ultimate goal of methodically and computationally design from scratch synthetic organisms with predetermined functions and controlled properties, with broad applications in medicine.


'/>"/>

Contact: Marie Guma-Diaz
m.gumadiaz@umiami.edu
305-284-1601
University of Miami
Source:Eurekalert

Page: 1 2

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientists identify novel inhibitor of human microRNA
3. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
4. MU scientists go green with gold, distribute environmentally friendly nanoparticles
5. Scientists identify gene that may contribute to improved rice yield
6. Scientists discover why a mothers high-fat diet contributes to obesity in her children
7. MU scientists see how HIV matures into an infection
8. Earth scientists keep an eye on Texas
9. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
10. Scientists identify a molecule that coordinates the movement of cells
11. Scientists Find new migratory patterns for Mediterranean and Western Atlantic bluefin tuna
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... the Department of Science and Technology in Society in ... Virginia Tech, has won a 2014 National Science Foundation ... and problems of creating a global nuclear emergency response ... Nuclear Power Plant in March 2011 was a turning ... Schmid said. Three of the plant,s six nuclear reactors ...
(Date:9/15/2014)... of the cheetah: The big predator is the fastest land ... just a few seconds. As it ramps up to top ... it reaches a full gallop. , Now MIT researchers have ... a robotic cheetah a sleek, four-legged assemblage of gears, ... its feline counterpart. The team recently took the robot for ...
(Date:9/15/2014)... no published account where hippopotamuses are demonstrably shown swimming ... water. But if they can,t swim, how did they ... accepted models for the methods, patterns, and timing of ... Crete, and Madagascar) may need to be reconsidered. , ... mainland are not currently supported by positive geological ...
Breaking Biology News(10 mins):'Nuclear disasters don't respect national boundaries' 2Run, cheetah, run 2Run, cheetah, run 3
... shift away from traditional coffee-growing techniques may be increasing ... that has swept through plantations in Central America and ... studies the disease. The current outbreak of coffee ... Mexico since the fungal disease arrived in the region ...
... stations could be drastically reduced by a new, energy-efficient ... releases it when exposed to sunlight. In a ... University and CSIRO scientists for the first time discovered ... of materials known for their exceptional capacity to store ...
... African-American women battling vitamin D deficiencies need the same ... to a recent study accepted for publication in The ... (JCEM). Although women with darker skin tones ... to measure Vitamin D levels, called 25-hydroxyvitamin D or ...
Cached Biology News:Modern growing methods may be culprit of 'coffee rust' fungal outbreak 2Modern growing methods may be culprit of 'coffee rust' fungal outbreak 3Carbon sponge could soak up coal emissions 2African-American, Caucasian women should take identical vitamin D doses 2
(Date:9/14/2014)... when it comes to survival strategies. They often create ... for example during treatment with antibiotics. A biofilm is ... slime capsule consisting of sugar chains and "curli". ... the first time created a detailed three-dimensional image of ... the bacterial cell wall, a crucial step in the ...
(Date:9/12/2014)... magnet using an electric field (magnetoelectric memory [MEM] ... next-generation technology for information processing and storage. Multiferroic ... due to the coexistence of electric and magnetic ... spontaneous electric and magnetic polarizations is rare in ... the MEM effect. This article briefly reviews a ...
(Date:9/12/2014)... Advancing the front lines of ... and biological threats is the mission of an ... (WPI) and the Georgian National Academy of Sciences, ... and Security Programme of the North Atlantic Treaty ... Workshop series, the event is titled “Nanotechnology to ...
(Date:9/12/2014)... Mountain View, CA (PRWEB) September 12, 2014 ... its fundraising campaign on Indiegogo. , The film, ... Stephen Hawking, Buzz Aldrin, Shimon Peres, Ashton Kutcher, Will.i.Am, ... changing the world and there’s only one university in ... it to help change the lives of a billion ...
Breaking Biology Technology:New insights in survival strategies of bacteria 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 3Documentary Film that Follows Singularity University Students as They Change the World Launches its IndieGoGo Fundraising Campaign 2
... , , , , , , ... Amex: NBS ) ("NeoStem" or the "Company"), an international,biopharmaceutical company ... it priced a public offering of 5,000,000 shares of its common ... after underwriting,discounts and commissions and expenses, will be approximately $5,697,500 ...
... , , , SHENYANG, ... Inc. (Nasdaq:, SSRX ) ("3SBio" or "the Company"), a ... manufacturing and marketing,biopharmaceutical products, and Ascentage Pharma Group Corporation, ... strategic,alliance to research, develop and commercialize best-in-class targeted cancer,therapeutics ...
... simple one-step process that produces both n-type and ... use of the promising material for future electronic ... used to increase conductivity in graphene nanoribbons used ... (SOG) material to graphene and then exposing it ...
Cached Biology Technology:NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 2NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 3NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 43SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 23SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 33SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 4Single-step technique produces both p-type and n-type doping for future graphene devices 2Single-step technique produces both p-type and n-type doping for future graphene devices 3