Navigation Links
Scientists uncover exciting lead into premature aging and heart disease
Date:4/30/2012

actually expected that knocking out Sun1 in these mouse models would worsen their conditions and cause them to die faster but surprisingly we observed the opposite. This is the first time that Sun1 protein has been implicated in diseases linked to Lamin A and it is exciting how basic research has led to a discovery that can potentially have significant impact on us," said Rafidah Abdul Mutalif, who is pursuing her PhD at IMB and one of the main authors of this paper.

Prof. Colin Stewart, Principle Investigator at IMB, said, "Notably, the heart muscle of the mice was restored to near normal function and cardiac function improved when the levels of SUN1 were reduced. Mutations in Lamin A are frequently reported as a cause of heart disease and especially within a group of hereditary cardiomyopathies. This opens up a possibility that from these observations, reduction in SUN1 maybe of therapeutic use for other forms of heart disease. We are very excited about this discovery and look forward to further pursuing this lead which could potentially lead to development of new treatments for heart diseases."


'/>"/>

Contact: Ong Siok Ming
ong_siok_ming@a-star.edu.sg
65-682-66254
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

Page: 1 2

Related biology news :

1. March of Dimes awards $250,000 prize to 2 scientists who pioneered advances in skin disorders
2. Scientists provide first large-scale estimate of reef shark losses in the Pacific Ocean
3. Stanford and MIT scientists win Perl-UNC Neuroscience prize
4. Queens is UK leader for female scientists and engineers
5. Scientists uncover strong support for once-marginalized theory on Parkinsons disease
6. Scientists develop new technique that could improve heart attack prediction
7. Scientists advance field of research with publication of newly validated method for analyzing flavanols in cocoa
8. Scripps research scientists find anticonvulsant drug helps marijuana smokers kick the habit
9. Scientists have discovered genes that increase the risk of osteoporosis and fractures
10. Marine scientists urge government to reassess oil spill response
11. Scientists find Achilles heel in life-threatening malaria parasites
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has announced the ... Security Systems Market" report to their offering. ... perimeter security market is estimated to grow at a CAGR ... holds a larger share in this market, Canada ...
(Date:12/17/2014)... 15, 2014  HITLAB SM announced today its completion ... its adherence to current U.S. Food and Drug Administration ... smart device and smart phone application trials utilizing the ... "HITLAB is determined to improve global healthcare access, ...
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of the ... their offering. One major trend emerging ... advances in technology, it is important to upgrade biometric ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... HOBOKEN, N.J. The Center for Science Writings at Stevens ... Versus Selfishness Among ,Wolf Birds," a talk by Bernd Heinrich, ... in the Babbio Center, Room 122, from 4 p.m. to ... Heinrich "not just a great naturalist writer; he,s a great ...
... Walter is one good gumshoe. The University of Alberta medical ... to glaucoma. , Glaucoma is a leading cause of blindness ... brain from understanding what patients see. Scientists have long suspected ... to figure out what the gene does and why some ...
... CA (March 20, 2009) A rigorous environmental cleaning ... Staphylococcus aureus (MRSA) and other multidrug-resistant organisms ... a new study released today at the annual ... America (SHEA). Researchers found that following an ...
Cached Biology News:Genetic sleuth solves glaucoma mystery 2Environmental cleaning intervention reduces transmission of multidrug-resistant organisms in ICUs 2
(Date:1/22/2015)... 22, 2015  Transwestern | RBJ today announces the firm brokered ... for Shire a leading biopharmaceutical company, at Two Ledgemont Center ... Robert Richards , president, and Brian Cohen , ... entire five-floor building at 95 Hayden Ave. Photo ...
(Date:1/22/2015)... 22, 2015 The laboratory information management ... witnessed a number of technological advancements due to factors ... growing need to integrate healthcare systems, and increasing government ... in system integration. Key players in the market focus ...
(Date:1/22/2015)... January 22, 2015 zFlo Motion , ... to announce an exciting product from a new partner. ... solutions over the past 15 years, with offerings in the ... their 3D IMU system (inertial measurement unit), iSen, is opening ...
(Date:1/22/2015)... NJ (PRWEB) January 22, 2015 ... technologies such as the Bioruptor® and complete solutions ... system for chromatin immunoprecipitation, alleviating the need for ... and controls needed for ChIP of histones or ...
Breaking Biology Technology:Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 43D Motion Capture Just Got Easy 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2
... April 11, 2012  Ikaria, Inc., a critical care ... for critically ill patients, today announced that Joseph ... In this role, Dr. Stauffer will be responsible ... regulatory activities related to Ikaria,s commercialized product, INOMAX® ...
... Advanced Biofuels, LLC, the biobutanol technology leader, commented ... patent infringement. (Logo: http://photos.prnewswire.com/prnh/20120209/MM50763LOGO ... for commercial production of isobutanol.  This is especially ... our ,188, ,889 and related patents filed by ...
... Systems Corporation has recently signed a strategic alliance ... Psyche,s award winning Anatomic Pathology solution, will be ... Lab, Siemens laboratory information system. ... is built on a contemporary architecture that is ...
Cached Biology Technology:Ikaria® Appoints Chief Medical Officer 2Ikaria® Appoints Chief Medical Officer 3Butamax™ Responds to Gevo Patent Infringement Lawsuit 2Psyche Systems Corporation Signs Strategic Alliance with Siemens Healthcare to Provide Anatomic Pathology Solutions 2
... The DNA quantitation kit is used to quantitate ... presence of RNA or protein. With this kit, ... can be detected with a VersaFluor or other ... of 10 ng per ml to 5 micrograms ...
... DeCypher combines enterprise-scale sequence analysis software with ... bioinformatics analyses. With DeCypher, you can perform searches ... ESTs vs NCBI NT database in under 6 ... to genomic DNA Use HMM analysis ...
...
Mouse polyclonal antibody to ALS2CR8 - amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8...
Biology Products: