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Scientists transform skin cells into functioning liver cells
Date:2/23/2014

nsplantation, the team noticed a boost in human liver protein levels in the mice, an indication that the transplanted cells were becoming mature, functional liver cells. Nine months later, cell growth had shown no signs of slowing down. These results indicate that the researchers have found the factors required to successfully regenerate liver tissue.

"Many questions remain, but the fact that these cells can fully mature and grow for months post-transplantation is extremely promising," added Dr. Willenbring, associate director of the UCSF Liver Center and the paper's other senior author. "In the future, our technique could serve as an alternative for liver-failure patients who don't require full-organ replacement, or who don't have access to a transplant due to limited donor organ availability."


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Contact: Anne Holden
anne.holden@gladstone.ucsf.edu
415-734-2534

Jeff Norris
JNorris@pubaff.ucsf.edu
415-476-8255

Gladstone Institutes
Source:Eurekalert


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