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Scientists track evolution and spread of deadly fungus, one of the world's major killers
Date:5/3/2011

gets in the future."

The researchers found that Cng in Thailand exhibits significantly less genetic diversity in comparison to other areas of the world, especially Africa where many different lineages of the pathogen occur. This suggests that populations of the fungus in Africa will have a wider spectrum of virulent strains and higher rates of adaptation to antifungal treatments, implying that clinicians need to pay particular attention to the risk of drug-resistant forms of the fungus here.

Their analysis also suggested that the pathogen was introduced from Africa to Asia at some point within the last 7,000 years. Many human infectious diseases are thought to have emerged within the last 11,000 years, following the rise of agriculture and domestication of animals. In particular, it supports the idea that the pathogen was imported via infected pigeons, which were domesticated around 5,000 years ago. The common pigeon, which originated in Africa, is considered to be a carrier and potential spreader of the fungus, its faeces being a common environmental source of Cng.


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Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

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