Navigation Links
Scientists take step toward simple and portable tuberculosis tests for developing world
Date:10/8/2009

Such a device could easily be built with existing off-the-shelf technology, says Krapf, adding that it would be no more complicated than the internal workings of a standard DVD player. The device relies on specialized surface chemistry that avoids protein adsorption, except for those molecules that need to be detected. Then, the presence of these molecules is recorded by fluorescence using a red diode laser.

Once detected, TB infections are generally treatable with a long course of antibiotics, and one of the basic strategies behind the World Health Organization's current efforts to curb the spread of the disease worldwide is to simply find the people who are infected and get them the antibiotics they need.

The CSU development could one day play a role in curbing the spread of TB. Currently, finding people who are infected is not so simple. Doctors can spot suspected cases by taking chest X-rays, which may reveal evidence of infection in the lungs. Or they can turn to a century-old technique called a sputum smear, where a sample of coughed fluid is stained and examined under a microscope for indications of the infection. Better yet, if doctors can grow cultures of TB bacteria from lung fluid, they definitively know that a person is infected.

These tests may not detect latent TB infections, however, because people who are latently infected may not have enough bacteria in their lungs to detect. For people with latent infections, other tests exist, but they have their problems as well. A simple skin test exists, but it is only sensitive enough to detect about half of all cases, says Krapf. Other more sophisticated methods that rely upon detecting specific markers in the blood are more sensitive, but they require special facilities and training that would be far too expensive for widespread use in the developing world.

Krapf and his colleagues have been able to demonstrate the feasibility of detecting markers of TB infections at
'/>"/>

Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Too much of a good thing? Scientists explain cellular effects of vitamin A overdose and deficiency
2. MDC scientists show how hematopoietic stem cell development is regulated
3. You must remember this: Scientists develop nasal spray that improves memory
4. Scientists discover clues to what makes human muscle age
5. Stimulus-funded university research addressing issues from climate change to cancer, creating jobs and training a new generation of scientists
6. Scientists join forces to explain HIV spread in Central and East Africa
7. Chinas new Climate Center welcomes citizen scientists
8. Help students think like soil scientists
9. Caltech scientists get detailed glimpse of chemoreceptor architecture in bacterial cells
10. 2 neuroscientists from Cold Spring Harbor Laboratory awarded transformative NIH grants
11. Scientists discover how to send insects off the scent of crops
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/11/2015)... and Markets ( http://www.researchandmarkets.com/research/3p32qm/access_control ) has announced ... Product, Application & By Geography - Global Forecast & ... This report predicts that the access control ... with an estimated CAGR of 10.6%. The ... as contact cards & readers, contactless cards & readers, ...
(Date:3/10/2015)... Transforming How We Look at ... in Human Space Flight" by Michael A. ... Ph.D. was recently featured by Springer Science Media, highlighting the ... Specifically, "Personalized Medicine in Human Space Flight" was ... 2013 and 2014 from Springer in the journal ...
(Date:3/5/2015)... PAULO , March 5, 2015 In ... 41 percent of companies already using these solutions and 42 ... 2015. Of the latter, approximately 25 percent of the companies ... While the majority of companies in the region ... anticipated that the hybrid model will command significant attention in ...
Breaking Biology News(10 mins):Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2"Personalized Medicine in Human Space Flight" Listed Among Most Influential Papers of 2013 and 2014 2Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 2Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 3Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 4
... D.C. The evolution of complex life forms may have ... events operating over millions of years caused large quantities of ... proposed in a new paper by Dominic Papineau of the ... have caused vast algal blooms, pumping extra oxygen into the ...
... EVANSTON, Ill. --- How do children reason about ... between human and non-human animals? For decades, the ... the biological world, they adopt an "anthropocentric" stance, favoring ... about properties of animals. But Northwestern University ...
... Even healthy pregnant women can be at risk for ... Reserve University began to understand which bacteria from the 700 ... health problem of preterm and stillbirths. Yiping Han ... Dental Medicine led the study, which found several new bacteria ...
Cached Biology News:Did phosphorus trigger complex evolution -- and blue skies? 2Animals talk, sing and act like humans? 2Even healthy pregnant women need to worry about oral bacteria 2
(Date:3/26/2015)... 2015  Roka Bioscience, Inc. (NASDAQ: ROKA ... advanced testing solutions for the detection of foodborne ... three months and full year ended December 31, ... for the quarter ended December 31, 2014 was ... quarter of 2013 and $1.5 million for the ...
(Date:3/26/2015)... 2015 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or the ... with certain matters, including the appointment of auditors, its ... 26, 2015 (the "Meeting") was adjourned, as previously disclosed ... 11:00 a.m. ( Toronto time). The ... that previous disclosed. The Meeting will reconvene at the ...
(Date:3/26/2015)... 2015  BioNano Genomics, Inc., the leader in genome ... as chief commercial officer. Salyer has more than 20 ... in life sciences. At BioNano, Salyer will oversee the ... platform to assemble a comprehensive view of complex genomes ... 32 institutions located in the United States ...
(Date:3/26/2015)... March 26, 2015 Neogen Corporation (NASDAQ: ... the third quarter of fiscal 2015, which ended Feb. ... prior year,s $6,575,000. Earnings per share in the current ... Current year-to-date net income increased 17% over prior year ... or $0.56 per share, for the same period a ...
Breaking Biology Technology:Roka Bioscience Reports Fourth Quarter and Full Year 2014 Financial Results 2Roka Bioscience Reports Fourth Quarter and Full Year 2014 Financial Results 3Roka Bioscience Reports Fourth Quarter and Full Year 2014 Financial Results 4Roka Bioscience Reports Fourth Quarter and Full Year 2014 Financial Results 5Roka Bioscience Reports Fourth Quarter and Full Year 2014 Financial Results 6Roka Bioscience Reports Fourth Quarter and Full Year 2014 Financial Results 7SQI Diagnostics Inc. Announces Adjournment of Meeting 2BioNano Genomics Appoints Terry Salyer as Chief Commercial Officer 2BioNano Genomics Appoints Terry Salyer as Chief Commercial Officer 3Neogen reports 13% increase in net income 2Neogen reports 13% increase in net income 3Neogen reports 13% increase in net income 4Neogen reports 13% increase in net income 5Neogen reports 13% increase in net income 6Neogen reports 13% increase in net income 7Neogen reports 13% increase in net income 8
... Sinovac Biotech Ltd. (Amex: SVA ),a leading provider ... CEO, and Ms. Helen Yang, International Business Manager, are ... All-Cap All-China Conference,on Monday, May 19, 2008 at 10:15 ... York, NY., Ms. Nan Wang, Vice President, and ...
... Calif., May 7 Jazz,Pharmaceuticals, Inc. (Nasdaq: JAZZ ... 2008 financial results on May 13, 2008, following the,close ... an,investor conference call and live audio webcast to discuss ... 5:00 p.m. Eastern Time/2:00 p.m.,Pacific Time., The live ...
... Mammography Revenue Growth and FDA Approval of Fujifilm CAD,Product Expected to Drive Growth ... ... Conference ... iCAD, Inc. (Nasdaq:,ICAD), an industry-leading provider of Computer-Aided Detection (CAD),solutions for the early ...
Cached Biology Technology:Sinovac to Present at the Brean Murray, Carret & Co. All-Cap All-China Conference and the Roth China Discovery Tour 2008 2Jazz Pharmaceuticals, Inc. to Announce First Quarter Results on May 13, 2008 2iCAD Reports First Quarter 2008 Financial Results 2iCAD Reports First Quarter 2008 Financial Results 3iCAD Reports First Quarter 2008 Financial Results 4iCAD Reports First Quarter 2008 Financial Results 5iCAD Reports First Quarter 2008 Financial Results 6iCAD Reports First Quarter 2008 Financial Results 7iCAD Reports First Quarter 2008 Financial Results 8iCAD Reports First Quarter 2008 Financial Results 9