Navigation Links
Scientists study full protein content of 'baker's yeast'
Date:2/17/2009

A scientist at the University of Liverpool will lead a 4 million study to analyse the entire protein content of 'baker's yeast' to further understanding of how living cells function.

Many proteins that have counterparts in the human body, such as cell cycle proteins and signalling proteins, were first discovered through the study of Saccharomyces cerevisiae a species of budding yeast, thought to have been originally isolated on the skins of grapes. Commonly used in baking and brewing it shares the complex cell structure of both plants and animals and has become a model organism for scientists studying areas such as metabolism, neurodegenerative disease and ageing.

Scientists have worked for many years to catalogue the proteins present in the yeast cell, but have yet to establish precisely how many copies of each protein are present and how they interact with each other. If researchers can quantify cellular proteins they will be able to understand more fully how cells operate and why in some cases they fail to perform their 'normal' function in the body.

Proteins in the body participate in every process of a cell from the contraction of muscles to immune response and scientists at the Universities of Liverpool and Manchester are using the yeast cell to understand how proteins perform these complex functions by using new proteomic technology.

Professor Rob Beynon, from the University's Proteomics and Functional Genomics Group, explains: "Our goal is to count the number of proteins inside a cell, to provide the essential link between genes and the proteins that they specify. To do this, we developed a new technology which uses artificial 'designer' proteins as tools to take a census of the proteins in a cell.

"The research should also allow us to determine how rapidly a cell builds and destroys proteins, and how they recycle the proteins that they no longer need. Understanding how all of these processes work is important to our knowledge of how the cell operates, and also allows us to develop models to predict the outcome when these systems go wrong in cases of disease. Surprisingly, approximately 20% of all genes associated with disease in humans have a counterpart in yeast."


'/>"/>

Contact: Samantha Martin
samantha.martin@liv.ac.uk
44-151-794-2248
University of Liverpool
Source:Eurekalert

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/16/2017)... FRANCISCO , Feb. 16, 2017  Genos, ... today announced that it has received Laboratory Accreditation ... CAP Accreditation is presented to laboratories that meet ... who demonstrate scientifically rigorous processes. "Genos ... excellence in laboratory practices. We,re honored to be ...
(Date:2/13/2017)... , Feb. 13, 2017  RSA Conference -- RSA, ... that is designed to enhance fraud detection and ... in the RSA Fraud & Risk Intelligence Suite. ... to leverage additional insights from internal and external ... better protect their customers from targeted cybercrime attacks. ...
(Date:2/10/2017)... , Feb 10, 2017 Research ... report "Personalized Medicine - Scientific and Commercial Aspects" ... ... medicine. Diagnosis is integrated with therapy for selection of treatment ... early detection and prevention of disease in modern medicine. Biochip/microarray ...
Breaking Biology News(10 mins):
(Date:2/22/2017)... Linda, Ca (PRWEB) , ... February 22, 2017 ... ... virtual events for tech innovators, engineers, and scientists from around the world, is ... will place on February 22 and 23, 2017. This premier, online-only conference focused ...
(Date:2/22/2017)... Dublin - Research ... Crop Protection (Bio-Pesticide) Market-By Type, By Application, By End User, By ... offering. ... Biological Crop Protection Market is forecasted to grow at a CAGR ... biopesticide or biological crop protection market is driven by the surging ...
(Date:2/22/2017)... 2017 Aethlon Medical, Inc. (Nasdaq: ... that validated the ability of the Aethlon HemopurifierĀ® to ... mortality in immune-suppressed sepsis patients and also contribute to ... objective of the study was to validate the ... (EBV) and Herpes Simplex virus 1 (HSV1) by the ...
(Date:2/22/2017)... ... February 22, 2017 , ... Pharma ... Tom Perkins as European director. Operating from Pennsideā€™s Zurich headquarters, Pennside Partners, GmbH, ... Perkins joins Pennside after more than a decade with leading market research firm, ...
Breaking Biology Technology: