Navigation Links
Scientists study full protein content of 'baker's yeast'
Date:2/17/2009

A scientist at the University of Liverpool will lead a 4 million study to analyse the entire protein content of 'baker's yeast' to further understanding of how living cells function.

Many proteins that have counterparts in the human body, such as cell cycle proteins and signalling proteins, were first discovered through the study of Saccharomyces cerevisiae a species of budding yeast, thought to have been originally isolated on the skins of grapes. Commonly used in baking and brewing it shares the complex cell structure of both plants and animals and has become a model organism for scientists studying areas such as metabolism, neurodegenerative disease and ageing.

Scientists have worked for many years to catalogue the proteins present in the yeast cell, but have yet to establish precisely how many copies of each protein are present and how they interact with each other. If researchers can quantify cellular proteins they will be able to understand more fully how cells operate and why in some cases they fail to perform their 'normal' function in the body.

Proteins in the body participate in every process of a cell from the contraction of muscles to immune response and scientists at the Universities of Liverpool and Manchester are using the yeast cell to understand how proteins perform these complex functions by using new proteomic technology.

Professor Rob Beynon, from the University's Proteomics and Functional Genomics Group, explains: "Our goal is to count the number of proteins inside a cell, to provide the essential link between genes and the proteins that they specify. To do this, we developed a new technology which uses artificial 'designer' proteins as tools to take a census of the proteins in a cell.

"The research should also allow us to determine how rapidly a cell builds and destroys proteins, and how they recycle the proteins that they no longer need. Understanding how all of these processes work is important to our knowledge of how the cell operates, and also allows us to develop models to predict the outcome when these systems go wrong in cases of disease. Surprisingly, approximately 20% of all genes associated with disease in humans have a counterpart in yeast."


'/>"/>

Contact: Samantha Martin
samantha.martin@liv.ac.uk
44-151-794-2248
University of Liverpool
Source:Eurekalert

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/13/2017)... March 13, 2017 Future of security: Biometric Face Matching ... ... DERMALOGs Face Matching enables to match face pictures against each ... to identify individuals. (PRNewsFoto/Dermalog Identification Systems) ... DERMALOG,s "Face Matching" is the fastest software for biometric Face Matching on ...
(Date:3/7/2017)... March 7, 2017   HireVue , the leading ... companies identify the best talent, faster, today announced the ... Officer (CSO) and Diana Kucer as Chief ... seasoned executive team poised to drive continued growth in ... a year of record bookings in 2017. ...
(Date:3/2/2017)... Who risk to be deprived of its imprint in ... https://www.reportbuyer.com/product/4313699/ WILL APPLE AND SAMSUNG CONFRONT EACH ... using capacitive technology represent a fast growing market, especially ... increase of 360% of the number of fingerprint sensor ... market between 2014 and 2017 (source : N+1 Singer, ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... ... March 28, 2017 , ... Currently symptomatic ... time. A recent study published in STEM CELLS suggests that human neural stem ... stem cells to produce more neural cells. , Strategies involving transplantation of ...
(Date:3/28/2017)... 28, 2017 /PRNewswire/ -RepliCel Life Sciences Inc. (OTCQB: REPCF) (TSXV: ... compelling safety and clinical data from its phase 1/2 tendon ... hair follicle-derived fibroblasts (RCT-01) as a treatment for Achilles tendinosis. ... ... safety profile at 6 months and showed no serious adverse ...
(Date:3/27/2017)... WARREN, N.J. , March 27, 2017 Roka ... providing advanced testing solutions for the detection of foodborne pathogens, ... at the Sidoti & Company Spring 2017 Convention on March ... the New York Marriott Marquis. About Roka ... ...
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... ... cancer (mCRC) generally produce small, heterogeneous samples with limited tumor content in a ... remain to be resolved, such as the need for reliable detection of low ...
Breaking Biology Technology: