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Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
Date:8/13/2007

proteins involved in energy production. Thus, for the first time, they were able to directly link inherited variation in the mitochondrial genome to metabolic markers for type 2 diabetes.

Our study highlights the role of mitochondrial DNA variation in common genetic diseases, says Dr. Theodore Kurtz, the lead investigator on the project. In addition, the animal models developed in this study will open the door for future studies in which the effects of mitochondrial genome variation can be investigated on fixed nuclear genetic backgrounds.


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Contact: Maria Smit
smit@cshl.edu
516-422-4127
Cold Spring Harbor Laboratory
Source:Eurekalert

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