Navigation Links
Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii
Date:6/17/2009

enome allowed the team of researchers to identify the genes involved in respiration, including those responsible for respiratory protection. Genome analysis helped pinpoint the chromosomal location of the three known oxygen-sensitive nitrogenases, as well as the genes that code for other oxygen-sensitive enzymes such as carbon-monoxide dehydrogenase and a formate dehydrogenase. The sequence also provided important information on the genes that code for alginate, a polymer that further protects the organism from excess oxygen by forming a physical barrier around the bacterium.

"A. vinelandii is an attractive model organism for biochemical studies because of its ability to produce high yields of quality enzymes," said Joo Setubal, associate professor at VBI and the Department of Computer Science at Virginia Tech. "The findings in this study provide new prospects for the wider application of this bacterium as a factory for the production and characterization of oxygen-sensitive proteins through the use of genetic approaches to achieve high-level protein expression."

According to Ray Dixon, project lead in Molecular Biology at the John Innes Centre in the United Kingdom, "The international collaboration created by the Azotobacter genome project was an integral part of the discovery of these unexpected anaerobic processes in A. vinelandii, which confirmed the importance of this organism as a host for the expression and purification of oxygen-sensitive enzymes."

The work will also provide more information about the unique biosynthetic pathways involved in the bacteria's ability to adapt its metabolism to diverse sources of nutrients. For example, if no carbon source is present, A. vinelandii will undergo a differentiation process, forming cysts that are resistant to desiccation and other chemical and physical challenges.

A. vinelandii belongs to the Pseudomonadaceae family. The completion of the A. vine
'/>"/>

Contact: Susan Bland
subland@vbi.vt.edu
540-231-7912
Virginia Tech
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Horse whisperers, lion tamers not needed: Scientists find genetic regions that soothe savage beasts
2. Scientists should look at their own carbon footprint
3. Scientists tackle the mystery of white-nose syndrome in bats
4. Scientists examine perceptions of risk and the spread of disease
5. Scientists discover new genetic immune disorder in children
6. Scientists uncover mode of action of enzyme linked with several types of cancer
7. Scientists unravel the mystery of white-nose syndrome
8. Seventy-three scientists elected to the American Academy of Microbiology
9. Scientists examine human behavior and the threat of disease
10. Singapore scientists elected into National Academy of Sciences
11. Scientists explain how death receptors designed to kill our cells may make them stronger
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... The Defense Logistics Agency is insourcing its efforts ... microcircuits from entering into its supply chain. ... initiative dubbed DNA marking. The capability will validate the ... the supply chain. The new quality control measures will ...
(Date:12/17/2014)... RALEIGH, N.C. , Dec. 16, 2014 Valencell, ... licensed its PerformTek biometric technology to industry leaders such ... highly accurate, clinically validated, biometric wearable products. These products ... 6-9 in Las Vegas . ...
(Date:12/17/2014)... , Dec. 16, 2014  Automation is fundamentally transforming ... than at international borders. Over the past decade, ePassports, ... travelers to self process through border control via eGates ... number of airports, seaports, and land borders across the ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... Panel of the American Association of Feline Practitioners ... feline patients based on risk assessment., From ... (2013) The American Association of Feline Practitioners, ... released updated guidelines on appropriate feline vaccination schedules ...
... process. Identification of important areas and species with ... objectives. China is one of mega-biodiversity countries of ... environmental degeneration, native and endemic species of China ... decades. It is an urgent agenda to set ...
... JPMorgan Chase & Co. (NYSE: JPM) and the Bill ... allow individual and institutional investors the opportunity to finance ... save millions of lives in low-income countries. ... investors including anchor support from Grand Challenges Canada ...
Cached Biology News:Appropriate vaccinations schedules for feline patients outlined 2Richness mapping and prediction of amphibians in Southern and Central China 2New investment fund will advance late-stage vaccines, other global health technologies 2New investment fund will advance late-stage vaccines, other global health technologies 3New investment fund will advance late-stage vaccines, other global health technologies 4
(Date:1/22/2015)... GEA Niro Soavi the leader in ... the PandaPLUS 2000, which is ideal for new applications ... cell disruption . This compact laboratory homogenizer is the ... food, food additives and ingredients as well as for ...
(Date:1/22/2015)... OH (PRWEB) January 22, 2015 Crystal Diagnostics ... today that it has received AOAC-PTM Certifications for the six ... O121, and O145; collectively referred to as STEC or the ... 1 colony forming unit (cfu) per 325 g of raw ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Selexis SA, ... mammalian Research Cell Banks (RCBs) used for drug discovery ... Cell Banks will include Next-Generation Sequencing (NGS) ... architecture de-risks biologic manufacturing by ensuring the integrity of ...
(Date:1/22/2015)... CAMBRIDGE, Mass. , Jan. 22, 2015   GenoSpace , ... suite of tools to enable the broad use of genomic, ... today announced the appointment of Michelle Munson , CEO ... independent director. Logo - http://photos.prnewswire.com/prnh/20150122/170713 ...
Breaking Biology Technology:GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2GenoSpace Expands Board with Appointment of Michelle Munson 2
... NV,(Euronext Brussels: THR), a biotechnology company focused on ... is today issuing a,business update for the nine ... De Haes, CEO of ThromboGenics, commenting on today,s,announcement, ... anticipated. We are now working hard to prepare ...
... 6 AmeriCares has,awarded its annual "Power ... global biotechnology, medical device and specialty pharmaceutical,company. ... Distribution,Management Association,s (HDMA) Annual Leadership Forum in ... award was created by AmeriCares and HDMA ...
... Calif., Nov. 6 ( http://www.amdl.com ),AMDL, Inc. ... with major operations in China and the U.S., ... Douglas MacLellan will present at,Rodman & Renshaw,s Annual ... 2008 at the New York Palace Hotel in ...
Cached Biology Technology:ThromboGenics N.V.: Business Update 2ThromboGenics N.V.: Business Update 3ThromboGenics N.V.: Business Update 4ThromboGenics N.V.: Business Update 5ThromboGenics N.V.: Business Update 6ThromboGenics N.V.: Business Update 7ThromboGenics N.V.: Business Update 8AmeriCares Presents 'Power of Partnership' Award to Baxter 2AmeriCares Presents 'Power of Partnership' Award to Baxter 3AMDL, Inc. New President & CEO Douglas MacLellan to Present at Rodman & Renshaw Annual Global Investment Conference November 12, 2008 2
... The new Finnigan Pocket Surveyor software ... and existing Finnigan Surveyor HPLC Systems. ... computer running the popular Windows Pocket ... the ability to connect directly to ...
... separation and fractionation of nucleic-acid ... nuclei from cytosolic proteins A ... greatly facilitating study of low-abundance ... acid binding proteins (e.g., transcription ...
... solution is an isotonic, balanced salt solution. It ... permits the storage of whole blood at refrigerator ... equal volume of blood is collected into a ... mixed. The solution is placed in a refrigerator ...
... Hollandes is a fixative useful for ... fixation. It is stable and will decalcify ... with Hollande's can be stained successfully with ... the solution stabilizes red blood cell membranes ...
Biology Products: