Navigation Links
Scientists reproduce evolutionary changes by manipulating embryonic development of mice
Date:7/30/2014

A group of researchers from the University of Helsinki and the Universitat Autnoma de Barcelona have been able experimentally to reproduce in mice morphological changes which have taken millions of years to occur. Through small and gradual modifications in the embryonic development of mice teeth, induced in the laboratory, scientists have obtained teeth which morphologically are very similar to those observed in the fossil registry of rodent species which separated from mice millions of years ago.

To modify the development of their teeth, the team from the Institute of Biotechnology of the University of Helsinki worked with embryonic teeth cultures from mice not coded by the ectodysplasin A (EDA) protein, which regulates the formation of structures and differentiation of organs in the embryo throughout its development. The teeth obtained with these cultures which present this mutation develop into very basic forms, with very uniform crowns. Scientists gradually added different amounts of the EDA protein to the embryonic cells and let them develop.

The researchers observed that the teeth formed with different degrees of complexity in their crown. The more primitive changes observed coincide with those which took place in animals of the Triassic period, some two hundred million years ago. The development of more posterior patterns coincides with the different stages of evolution found in rodents which became extinct already in the Palaeocene Epoch, some 60 million years ago. Researchers have thus achieved experimentally to reproduce the transitions observed in the fossil registry of mammal teeth.

The team of scientists were able to contrast the shape of these teeth with a computer-generated prediction model created by Isaac Salazar-Ciudad, researcher at the UAB and at the University of Helsinki, which reproduces how the tooth changes from a group of equal cells to a complex three-dimensional structure, with the full shape of a molar
'/>"/>

Contact: Isaac Salazar-Ciudad
Isaac.salazar@uab.cat
34-935-812-730
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1 2

Related biology news :

1. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
2. Queens scientists seek vaccine for Pseudomonas infection
3. Scientists produce eye structures from human blood-derived stem cells
4. American Society of Plant Biologists honors early career women scientists
5. Brandeis scientists win prestigious prize for circadian rhythms research
6. Scientists discover new method of proton transfer
7. Salk scientists open new window into how cancers override cellular growth controls
8. WileyChina.com - Now Featuring Bespoke Pages for China’s Life Scientists
9. Scientists win $2 million to study new pathway in development and maintenance of lymphoma
10. UGA scientists reveal genetic mutation depicted in van Goghs sunflower paintings
11. Genetic mutation depicted in van Goghs sunflower paintings revealed by scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2015)... 14, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... focused on the growing mobile commerce market, announces that ... 2015 New York Design Awards under the category  ,Product ... City Design Awards are part of a global multi-disciplinary ... ratings from the marketplace, industry and judging panel. Winners ...
(Date:4/13/2015)... April 13, 2015  higi, a leading cloud-based consumer ... more fully engage with their communities around health and ... protected and secure API.  ... most accessible, affordable, and convenient vehicle to receive validated ... The API will allow higi,s trusted ...
(Date:4/9/2015)... April 9, 2015 Synaptics Inc. (NASDAQ: SYNA ... today that it will report financial results for the ... 2015, after the close of market. The company will ... at 2:00 p.m. PT (5:00 p.m. ET), during which ... participate on the live call, analysts and investors should ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3Synaptics to Report Third Quarter Results on April 23 2
... endometrium (uterine lining) and transplanted into the brains of ... of brain cells damaged by the disease, according to ... The findings are published in the ... are preliminary results, the findings increase the likelihood that ...
... NEW YORK (May 6, 2010) The Wildlife ... of a large, "landscape-wide" conservation approach to protect globally ... study looked at wildlife populations in northern Republic of ... national park, a community-managed reserve, and various logging concessions. ...
... produced the first whole genome sequence of the 3 billion ... that up to 2 percent of the DNA in the ... or in Neanderthals, ancestors. The international research ... Institute (NHGRI), part of the National Institutes of Health, reports ...
Cached Biology News:Endometrial stem cells could repair brain cells damaged by Parkinson's disease 2Study looks at gorillas, elephants and logging in Congo 2Study looks at gorillas, elephants and logging in Congo 3Complete Neanderthal genome sequenced 2Complete Neanderthal genome sequenced 3Complete Neanderthal genome sequenced 4Complete Neanderthal genome sequenced 5
(Date:5/1/2015)... , May 1, 2015 ... Production Market by Product (Equipment, Consumables), by Type (Monoclonal, ... Diagnostic Labs, Research Institutes) - Analysis & Global ... studies the global Antibody Production Market for the ... is expected to reach $2.572 Billion by 2019 ...
(Date:4/30/2015)... Spirax Sarco, the leader in product ... announce that for the first time in the company’s ... a Queen’s Award for Innovation – the UK’s highest ... of a unique flowmeter. , The Spirax Sarco ... steam flow measurement. The device provides reliable, accurate ...
(Date:4/30/2015)... --  Tamir Biotechnology , a leading developer of RNA ... antiviral therapy program. Clinical Progress ... evaluated and considered by a number of clinicians on ... first quarter of 2015, the company participated in the ... of Potential Treatments and Vaccines For Ebola In West ...
(Date:4/30/2015)... /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ), an ... has commenced an underwritten public offering of its common ... a 30-day option to purchase up to an additional ... in the public offering. The offering is subject to ... to whether or when the offering may be completed, ...
Breaking Biology Technology:Antibody Production Market worth $2.572 Billion by 2019 2Antibody Production Market worth $2.572 Billion by 2019 3Antibody Production Market worth $2.572 Billion by 2019 4Spirax Sarco Receives a Queen’s Award for Innovation 2Spirax Sarco Receives a Queen’s Award for Innovation 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 2Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 4BioAmber Inc. Announces Public Offering Of Common Stock 2BioAmber Inc. Announces Public Offering Of Common Stock 3
... VoIP (voice over internet protocol) has been a long time ... have been nervously looking over our shoulder as VoIP technology ... first greeted it with a confident snicker or brash statements ... work, they dont understand Telephony! But time passed and Telephonys ...
... topics of this newsletter hit a nerve as sharply as social ... on this topic than I seem to receive on all other ... things get a little lonely in my office.) , ,Last week, ... fundamental sense." , ,I said, "The value is in actively ...
... The MIT Club of Wisconsin is recognizing nPoint, ... technological innovation. nPoint, a Madison-based provider of motion devices ... of three winners of the annual 2004 MIT Club ... Club of Wisconsin consists of alumni of the Massachusetts ...
Cached Biology Technology:A telecom person in an VoIP world 2Social networks: Readers respond 2Social networks: Readers respond 3Social networks: Readers respond 4
Request Info...
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5...
...
RayBio L Series 507: RayBio Label-based Antibody Array I (1 glass slide with 2 subarrays) Class: Antibody Array Products Product Group: Antibody Array...
Biology Products: