Navigation Links
Scientists reduce behaviors associated with problem gambling in rats
Date:10/29/2013

With the help of a rat casino, University of British Columbia brain researchers have successfully reduced behaviours in rats that are commonly associated with compulsive gambling in humans.

The study, which featured the first successful modeling of slot machine-style gambling with rats in North America, is the first to show that problem gambling behaviours can be treated with drugs that block dopamine D4 receptors. The findings have been published in Biological Psychiatry journal.

"More work is needed, but these findings offer new hope for the treatment of gambling addiction, which is a growing public health concern," says Paul Cocker, lead author of the study and a PhD student in UBC's Dept. of Psychology. "This study sheds important new light on the brain processes involved with gambling and gambling addictions."

For the study, rats gambled for sugar pellets using a slot machine-style device that featured three flashing lights and two levers they could push with their paws. The rats exhibited several behaviours associated with problem gambling such as the tendency to treat "near misses" similar to wins.

Building on previous research, the team focused on the dopamine D4 receptor, which has been linked to a variety of behavioural disorders, but never proven useful in treatment. The study found that rats treated with a dopamine D4 receptor-blocking medication exhibited reduced levels of behaviours associated with problem gambling.

While findings suggest that blocking the D4 dopamine receptor may help to reduce pathological gambling behaviours in humans, the researchers note that further research is needed before the drugs can be considered a viable pharmaceutical treatment for pathological gambling in humans.


'/>"/>

Contact: Basil Waugh
basil.waugh@ubc.ca
604-822-2048
University of British Columbia
Source:Eurekalert

Page: 1

Related biology news :

1. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
2. Queens scientists seek vaccine for Pseudomonas infection
3. Scientists produce eye structures from human blood-derived stem cells
4. American Society of Plant Biologists honors early career women scientists
5. Brandeis scientists win prestigious prize for circadian rhythms research
6. Scientists discover new method of proton transfer
7. Salk scientists open new window into how cancers override cellular growth controls
8. WileyChina.com - Now Featuring Bespoke Pages for China’s Life Scientists
9. Scientists win $2 million to study new pathway in development and maintenance of lymphoma
10. UGA scientists reveal genetic mutation depicted in van Goghs sunflower paintings
11. Genetic mutation depicted in van Goghs sunflower paintings revealed by scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... Fla. , April 11, 2017 ... and secure authentication solutions, today announced that it ... Intelligence Advanced Research Projects Activity (IARPA) to develop ... Thor program. "Innovation has been a ... IARPA,s Thor program will allow us to innovate ...
(Date:4/5/2017)... , April 5, 2017  The Allen Institute ... Allen Cell Explorer: a one-of-a-kind portal and dynamic digital ... 3D imaging data, the first application of deep learning ... human stem cell lines and a growing suite of ... platform for these and future publicly available resources created ...
(Date:3/30/2017)... 2017  On April 6-7, 2017, Sequencing.com will host ... hackathon at Microsoft,s headquarters in Redmond, ... on developing health and wellness apps that provide a ... Genome is the first hackathon for personal genomics ... companies in the genomics, tech and health industries are ...
Breaking Biology News(10 mins):
(Date:4/27/2017)... ... April 27, 2017 , ... Oncolinx, a spin-out ... Startup Competition, has truly taken their cancer research out of this world. On ... from Cape Canaveral to the International Space Station’s (ISS) U.S. National Laboratory, managed ...
(Date:4/27/2017)... ... April 27, 2017 , ... Mitotech S.A, a Luxembourg based clinical stage biotechnology ... patients. LHON is a rare devastating genetic disease that leads to a sudden and ... group of 20 patients carrying 11778, 14484 and 3460 mutations and having experienced the ...
(Date:4/27/2017)... ... April 27, 2017 , ... Arrowhead Publishers is pleased to ... coming to San Diego, CA on September 27-28, 2017. Leaders from the pharmaceutical, ... advances in the treatment of various types of pain. There are also extended ...
(Date:4/27/2017)... ... 27, 2017 , ... Sierra Instruments announces the ... thermal mass flow technology provide exponentially more accurate mass flow data than volumetric ... all industrial processes—such as those involving chemical reactions, combustion, respiration, pharmaceutical, and HVAC—require ...
Breaking Biology Technology: