Navigation Links
Scientists ramp up ability of poplar plants to disarm toxic pollutants
Date:10/15/2007

l pollutants that pose serious health effects. Some of these are known carcinogens," Doty, an assistant professor of forest resources, said.

Trichloroethylene is a heavily used industrial degreaser that's made its way into groundwater because of improper disposal. Both unaltered poplars and the transgenic poplar plants produce the enzymes to break down trichloroethylene, C2HCl3, into chloride ions harmless salt that the plant sheds and recombines the carbon and hydrogen with oxygen to produce water and carbon dioxide.

The transgenic poplar plants just do it a lot faster. The enzymes used to metabolize the contaminants are from a group called cytochrome P450 found in both plants and animals. Poplars have a lot of P450s and Doty said scientists hope to eventually sort them to find ways to manipulate the plant's own genes to ramp up pollution degradation. In the meantime they are conducting experiments inserting a gene that produces cytochrome P450 in mammalian livers, in this case the livers of rabbits. Poplar genes producing cytochrome P450 is expressed in all their cells, but not at the rates achieved by the transgenics.

"We overcame the rate-limiting step by causing the poplar plants to overexpress the first enzyme in the degradative pathway," Doty said. "Using the mammalian gene is just a step toward the day when we understand the poplar P450 genes well enough to use promoters to enhance production of their own enzymes that degrade contaminants. With the plant's own genes, the results should be even better."

Mammalian cytochrome P450 has already been used in transgenic plants that can detoxify herbicides applied to fields to kill weeds. Japanese researchers, for example, published findings in 2005 about using a human gene to make rice plants degrade a suite of herbicides, something they said could help reduce the load of herbicides in paddy fields and streams.

Along with the trichloroethylene tests, the new results also found improved
'/>"/>

Contact: Sandra Hines
shines@u.washington.edu
206-543-2580
University of Washington
Source:Eurekalert

2

GOOD

Page: 1 2 3 4

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
3. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
4. UAB scientists discover the origin of a mysterious physical force
5. Fox Chase Cancer Center scientists identify immune-system mutation
6. Scientists Replicate Hepatitis C Virus in Laboratory
7. Scientists detect probable genetic cause of some Parkinsons disease cases
8. Scientists find missing enzyme for tuberculosis iron scavenging pathway
9. Scientists seek answers on what activates deadly anthrax spores
10. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
11. Scientists collaborate to assess health of global environment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... Scientists investigating the interaction of a group of proteins ... damage have identified a new target that could increase ... the University,s School of Biochemistry and published in the ... Reviews, could eventually lead to new therapies for stroke ... earlier work by the team which identified a protein, ...
(Date:5/17/2013)... MD The Federation of American Societies for Experimental ... National Institutes of Health (NIH) funding trends highlighting the ... support critical research. The FASEB analysis follows a May ... Collins, MD, PhD, who testified that the $1.6 billion ... sequestration is "having a substantial impact on the scientific ...
(Date:5/16/2013)... MD FASEB MARC (Maximizing Access to Research ... for The Society for Developmental Biology (SDB) 72nd ... 2013. These awards are meant to promote the ... groups into the mainstream of the basic science ... scientists at the SDB 2013 Annual Meeting. , ...
Breaking Biology News(10 mins):SUMO wrestling cells reveal new protective mechanism target for stroke 2
... pleased to announce an exclusive commercial license agreement ... plants and with important implications for crop improvement. ... is licensing the technology to Dow AgroSciences. Dow ... Chemical Company (NYSE: DOW), entered into an exclusive ...
... evolve for months after a traumatic brain injury (TBI), ... trauma, new research led by the University of Melbourne, ... Victorian Neurotrauma Initiative is published in the latest issue ... Around 400,000 Australians have a disability related to ...
... help from their female friends are far more successful as ... new study. , Previous research into reproductive success in animal ... benefits of inherited genetic characteristics, while others show the benefits ... uncle or other unrelated helpers. , The new ...
Cached Biology News:Dow Agrosciences licenses exclusive novel crop enhancement technology 2Study provides treatment hope for long term effects of brain trauma 2Successful mothers get help from their friends: Dolphin study 2
(Date:5/21/2013)... Savoury Systems International (SSI), a leader in the ... USA Sales Broker. Braddy’s new role will allow SSI ... , In 2004 Braddy founded Southeastern Food ... processors and industrial manufacturers. Braddy has worked for ... has over 25 years of sales management experience. ...
(Date:5/21/2013)... (PRWEB) May 21, 2013 Smarter Security, ... security solutions, today announced that Genzyme, a Sanofi company ... of Door Detective® CL for a multi-use facility in ... in four other Genzyme buildings, this latest order underscores ... the tailgate detection device improving doorway access ...
(Date:5/21/2013)... Toronto, Canada (PRWEB) May 21, 2013 ... there is a strong push within the industry ... Development and Manufacturing Organizations and pharma companies often ... time frames. , Microtablets, developed in collaboration with ... how effective outsourcing can bring products to market ...
(Date:5/21/2013)... Norristown, PA (PRWEB) May 21, 2013 ... company, today announced that Dr. Charles Signorino, the Company’s ... on April 1, 2013 after 32 years of service. ... Adolfo Gomez, Emerson’s current President, has been named as ... recognized luminary in the pharmaceutical industry, having made a ...
Breaking Biology Technology:Door Security at Genzyme, a Sanofi Company, Enhanced with Door Detective from Smarter Security 2Door Security at Genzyme, a Sanofi Company, Enhanced with Door Detective from Smarter Security 3The Development of an Innovative Microtablet Dosage Form, a Success Story: Live Webinar Hosted by Xtalks 2Emerson Resources Announces CEO Retirement and Appointment of Successor 2Emerson Resources Announces CEO Retirement and Appointment of Successor 3
... ... cGMP manufacturer, announced that the company is in the initial phases of a multi-year ... Ingredient (API) manufacturing facility located in Riverview, Michigan. Expansions will include a new reactor ... ...
... , CRANBURY, N.J., Sept. 30 Amicus Therapeutics (Nasdaq: ... 1 study of AT2220 (1-deoxynojirimycin HCl), its investigational drug in ... objective of this study is to evaluate the pharmacokinetics of ... U.S. Food and Drug Administration (FDA) has agreed to Amicus, ...
... Despite a number of key issues such as ... and feed uses, global use of biofuels is excepted to ... new global analysis released today by Hart,s Global Biofuels Center. ... of total biofuels use of more than 35%. Brazil will ...
Cached Biology Technology:Ash Stevens Plans $6 Million Facility Expansion to Bolster CMC Capabilities 2Amicus Therapeutics Announces Plan to Initiate Phase 1 Study of AT2220 for Pompe Disease 2Amicus Therapeutics Announces Plan to Initiate Phase 1 Study of AT2220 for Pompe Disease 3Amicus Therapeutics Announces Plan to Initiate Phase 1 Study of AT2220 for Pompe Disease 4Global Biofuels Growth to Double by 2015 2Global Biofuels Growth to Double by 2015 3Global Biofuels Growth to Double by 2015 4
Rat Aortic Smooth Muscle Cells (RAOSMC) (>500,000 cells)...
Rat Aortic Endothelial Cells (RAOEC) (>500,000 cells)...
... The Brownlee Precision Model 440 incorporates ... circuitry in a friendly easy-to-use instrument. Each ... amplifier, an 8-pole Bessel lowpass filter, a ... output offset controls. A control knob sets ...
... fully licensed, high throughput, water bath thermal cycler ... 24 microplates. This equates to 9,216 reactions per ... robotic arm rapidly transfers a basket of plates ... times that are considerably faster than those of ...
Biology Products: