Navigation Links
Scientists pinpoint key defense against parasite infection

Scientists have made a significant discovery about how the body defends itself against snail fever, a parasitic worm infection common in developing countries.

Researchers studied the immune response in mice infected with snail fever parasites. They found that a particular type of immune cell, known as the dendritic cell, is responsible for triggering the immune system's defence against the invading parasite.

The development, by scientists at the University of Edinburgh, could point towards new avenues of research into treatments for the condition, which causes long-term infection.

Snail fever, also known as bilharzia, is a water-borne potentially fatal disease caused by flukes or parasitic worms found in freshwater snails in the tropics. Common in developing countries in Asia, Africa and South America, the condition causes chronic illness that can damage internal organs and impair growth and brain development in children.

The disease, which commonly affects tourists who kayak or swim in infected waters, is second only to malaria in terms of its devastating social and economic impact.

The study, published in the Journal of Experimental Medicine, was carried out in collaboration with the German Cancer Research Centre in Heidelberg and funded by the Medical Research Council and the Wellcome Trust.

Dr Andrew MacDonald, of the University of Edinburgh's School of Biological Sciences, who led the research, said: "Until now, we were unsure which of the many cells found in the immune system were crucial to fighting this parasite. We now know that dendritic cells are key to the process. If we can manipulate this immune response, we stand a chance of targeting the widespread suffering and chronic illness caused by this infection."


Contact: Catriona Kelly
University of Edinburgh

Page: 1

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientists identify novel inhibitor of human microRNA
3. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
4. MU scientists go green with gold, distribute environmentally friendly nanoparticles
5. Scientists identify gene that may contribute to improved rice yield
6. Scientists discover why a mothers high-fat diet contributes to obesity in her children
7. MU scientists see how HIV matures into an infection
8. Earth scientists keep an eye on Texas
9. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
10. Scientists identify a molecule that coordinates the movement of cells
11. Scientists Find new migratory patterns for Mediterranean and Western Atlantic bluefin tuna
Post Your Comments:
(Date:11/18/2015)... York , November 18, 2015 ... Research has published a new market report titled  Gesture ... Trends, and Forecast, 2015 - 2021. According to the report, ... 2014 and is anticipated to reach US$29.1 bn by ... 2021. North America dominated ...
(Date:11/17/2015)... Paris , qui s,est tenu ... Paris , qui s,est tenu du 17 au ... l,innovation biométrique, a inventé le premier scanner couplé, qui ... même surface de balayage. Jusqu,ici, deux scanners étaient nécessaires, ... digitales. Désormais, un seul scanner est en mesure de ...
(Date:11/17/2015)... , Nov. 17, 2015 Pressure BioSciences, Inc. ... the development and sale of broadly enabling, pressure cycling ... sciences industry, today announced it has received gross proceeds ... million Private Placement (the "Offering"), increasing the total amount ... or more additional closings are expected in the near ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... , President and CEO of Neurocrine Biosciences, will be ... in New York . ... the website approximately 5 minutes prior to the presentation ... of the presentation will be available on the website ...
(Date:11/25/2015)... ... November 25, 2015 , ... A long-standing ... Aerospace Professionals (OPBAP) has been formalized with the signing of a Memorandum of ... with OPBAP leaders Capt. Karl Minter and Capt. Albert Glenn Tuesday, November 24, ...
(Date:11/25/2015)... , November 25, 2015 ... Report is a professional and in-depth study on ...      (Logo: ) , ... the industry including definitions, classifications, applications and industry ... for the international markets including development trends, competitive ...
(Date:11/24/2015)... KUALA LUMPUR, Malaysia , Nov. 24, 2015 ... the global contract research organisation (CRO) market. The ... to result in lower margins but higher volume ... With increased capacity and scale, however, margins in ... Contract Research Organisation (CRO) Market ( ...
Breaking Biology Technology: