Navigation Links
Scientists offer way to address 'age-old' questions
Date:9/7/2011

Scientists have devised a method to measure the impact of age on the growth rates of cellular populations, a development that offers new ways to understand and model the growth of bacteria, and could provide new insights into how genetic factors affect their life cycle. The research, which appears in Evolution: International Journal of Organic Evolution, was conducted by scientists at New York University and the University of Tokyo.

When bacterial cells age, their capacity for reproduction is reduced. Individual cells within populations are subject to the force of selection, which results from differences in growth rates. Broadly speaking, growing populations are dominated by relatively young cells. A population's age structure, however, depends sensitively on the interplay between selection and the reproductive capacities of the cells.

The researchers sought to understand how changes in cells' reproductive capacity would affect the population's growth rate. This question dates back to seminal research in population genetics by Ronald Fisher in the 1930s and William Hamilton in the 1960s. Typically, the answer is indirect, and relies on a measured life table and reproductive capacity, which takes into account survival and birth rates.

The NYU and University of Tokyo researchers hypothesized that a more direct gauge would be to examine the bacteria's lineagestheir history over several generations. In other words, they proposed looking backward several generations into the population's tree of cell divisions. This allowed them to directly measure the response of the bacteria's growth rate to age-specific changes in mortality and reproductive capacity.

"The force of selection within populations leaves key signatures in the population's lineage tree," said Edo Kussell, a professor of biology at NYU's Center for Genomics and Systems Biology and the study's corresponding author. "Theory allows us to interpret these in po
'/>"/>

Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientists identify novel inhibitor of human microRNA
3. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
4. MU scientists go green with gold, distribute environmentally friendly nanoparticles
5. Scientists identify gene that may contribute to improved rice yield
6. Scientists discover why a mothers high-fat diet contributes to obesity in her children
7. MU scientists see how HIV matures into an infection
8. Earth scientists keep an eye on Texas
9. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
10. Scientists identify a molecule that coordinates the movement of cells
11. Scientists Find new migratory patterns for Mediterranean and Western Atlantic bluefin tuna
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... 2014  That blood pressure plays a role in human ... the medical term for high blood pressure – was first ... inflatable cuff that,s used in measuring blood pressure was invented ... new about hypertension, its triggers and its effects. In fact, ... and the best ways to treat it. For ...
(Date:12/10/2014)... 2014  Valencell, a leader in performance biometric data ... demand from its licensees for highly accurate, clinically validated ... solely coming from fitness and health sectors, but first ... wearable is only as useful as the biometric data ... driver in long-term mass consumer adoption of wearable products," ...
(Date:12/10/2014)... DUBLIN , Dec. 08, 2014 Research ... announced the addition of the "Biometrics Market ... http://photos.prnewswire.com/prnh/20130307/600769 ... for projects such as rural banking and upgradation ... major trends witnessed in the market. Besides the ...
Breaking Biology News(10 mins):Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Wearable Technology Products Demand Highly Accurate Biometric Technology 2Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2
... has evolved a unique technique for sensing motion may inspire ... active sonar. Although members of the fish ... environment and the movement of water around them with gel-covered ... underwater objects and navigate through their lightless environment inspired a ...
... a traffic accident with personal injury is significantly higher ... use of codeine alone does not carry an increased ... Norwegian Institute of Public Health. Codeine and ... mild to moderate pain. In Norway, codeine is included ...
... 2009 / b3c newswire / -  LabRoots Inc. ... social networking site for the scientific community. Beginning today, ... to LabRoots.com to begin building relationships with other scientists ... from giving scientists a place to share their expertise ...
Cached Biology News:Researchers develop flow sensors based on hair structures of blind cavefish 2Researchers develop flow sensors based on hair structures of blind cavefish 3Codeine use and accident risk 2LabRoots Launches Social Networking Site for Scientists & Engineers 2
(Date:12/19/2014)... , Dec. 19, 2014 Naurex Inc., a ... drugs for diseases of the central nervous system, today ... chief executive officer, will present at the 33 rd ... will take place at 3:00 p.m. PST on Tuesday, ... San Francisco, Calif. ...
(Date:12/19/2014)... , Dec. 19, 2014 Decision Resources ... will grow at a 12 percent compound annual growth ... of the aging population and the increasing adoption of ... America will also spur demand for dental ... dental implant and periodontal treatments. Other key ...
(Date:12/19/2014)... (PRWEB) December 18, 2014 Today, ... locate its pilot production facility and future company ... and produce innovative new materials that safely and ... not only because of its historic, strong support ... efforts to attract leading edge, technology-based companies such ...
(Date:12/19/2014)... Reports from CDC show approximately ... one or more chronic health conditions - including cardiovascular ... some of these diseases, but may not eliminate the ... While implanted nerve stimulation devices today offer relief, they ... can induce side effects. , To eliminate the ...
Breaking Biology Technology:Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 4Draper Wins GSK Funding for Smaller, Smarter Implantable Devices 2
... 2011 Informex , the leading meeting ... today announced the introduction of a new conference, ... the Biopharmaceutical Evolution, to be hosted October 5-6th, ... will cover on-trend topics regarding the future of ...
... announced that the Company,s Chief Scientific Officer, Graeme Doran, ... Drug Discovery & Diagnostic Development Week, in San Francisco. ... the application of next generation sequencing technology for research, ... on "Next Generation Sequencing & Genomic Medicine." He will ...
... Aug. 2, 2011 Enzymatics, Inc., ( www.enzymatics.com ) ... the Greater Boston Chamber of Commerce with a "Top ... Honorees include dynamic small and high growth ... performance, workplace excellence, product innovation, and social responsibility.  An ...
Cached Biology Technology:New Conference Offers Solutions for Success in the Growing Biologics Market 2New Conference Offers Solutions for Success in the Growing Biologics Market 3Pathogenica CSO Speaks at IBC Life Sciences Drug Discovery & Diagnostic Development Week 2Enzymatics Honored With a Top 10 Small Business of the Year Award 2
... SpeedVac™ Concentrators set the standard for sample concentration ... with large chamber uses a combination of centrifugal ... in a single run. , SC210A comes equipped ... for long lasting chemical compatibility ...
Digital display of time, vacuum and temperature , Dual vacuum control of ramping rate and ultimate level , Comes complete with RH40-12 (40 x 1.5 ml) Rotor and (2) Glass Condensation Flasks. ...
... series of vacuum concentrators/centrifugal evaporators offers a ... to rapid and safe concentration of heat-labile ... with oil-free or high vacuum pumps, a ... selection of rotors (eliminating sample loss by ...
... George Paxinos Affiliation: School of Psychology, The University ... Affiliation: Curtin University of Technology, Perth, Australia This ... of the rat brain. It is a ... revison and extension of the compact 3rd edition. ...
Biology Products: