Navigation Links
Scientists join forces to explain HIV spread in Central and East Africa
Date:9/29/2009

to follow the virus' molecular footprints since its emergence in the 1920s.

"HIV mutates rapidly," said Rebecca Gray, a postdoctoral associate in the department of pathology, immunology and laboratory medicine. "This is a successful strategy for the virus, because it evolves quickly and develops drug resistance. But we can use these changes in the genome to follow it over time and develop a history of its progress."

Researchers wanted to know why, the virus smoldered during the 1950s and `60s, before spreading like wildfire through east Africa in the 1970s.

A fateful piece of the puzzle came in the form of geographic information system data, which uses satellite imagery and painstakingly takes into account the availability and navigability of roads between population centers, transportation modes, elevation, climate, terrain and other factors that influence travel.

"We were able to use geographic data to interpret the genetic data," said Andrew J. Tatem, Ph.D., an assistant professor of geography in the College of Liberal Arts and Sciences and a member of UF's Emerging Pathogens Institute. "Genetic data showed once HIV moved out of the Democratic Republic of Congo, it expanded fast and moved rapidly across Uganda, Kenya and Tanzania, all while staying at low levels in the DRC. What was happening was the virus was circulating at stable levels in the urban centers of the DRC, but these centers were isolated. Once it hit east Africa, connectivity between population centers combined with better quality transportation networks, and higher rates of human movement caused HIV to spread exponentially."

HIV was prevalent in about 15 percent of the population in Kenya in 1997, although it has since dropped to about 7 percent, according to the Kaiser Family Foundation. As of 2007, an estimated 22 million people were living with HIV/AIDS in sub-Saharan Africa. About 1.1 million Americans have HIV or AIDS, and an estimated 5.1 millio
'/>"/>

Contact: John Pastor
jdpastor@ufl.edu
352-273-5815
University of Florida
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Chinas new Climate Center welcomes citizen scientists
2. Help students think like soil scientists
3. Caltech scientists get detailed glimpse of chemoreceptor architecture in bacterial cells
4. 2 neuroscientists from Cold Spring Harbor Laboratory awarded transformative NIH grants
5. Scientists discover how to send insects off the scent of crops
6. Duke biomedical scientists win 2 highly prized NIH Directors Awards
7. UNC scientists garner new NIH awards for high risk, transformative research
8. Scientists outline planetary boundaries: A safe operating space for humanity
9. Ocean observing scientists and marine industries teaming up to sustainably monitor the water column
10. University of Iowa scientists use blood-brain barrier as therapy delivery system
11. Scientists discover key factor in regulating placenta and fetal growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists join forces to explain HIV spread in Central and East Africa
(Date:7/9/2014)... July 9, 2014Biofuels derived from the oils produced by ... fuels. To achieve this goal, optimization of cost effective ... pond systems, is needed. Sapphire Energy has developed an ... pond algae cultivation systems, described in Industrial Biotechnology ... publishers. The article is available on the Industrial ...
(Date:7/9/2014)... Cancer Genome Atlas (TCGA) Research Network have identified ... lung adenocarcinoma, the most common subtype of lung ... the number of possible therapeutic targets for this ... patients with treatable mutations because many potent cancer ... TCGA is jointly funded and managed by the ...
(Date:7/9/2014)... era of increasing concern about the prevalence of ... a promising new pathway to disabling disease: blocking ... The scientists showed how bacterial siderophore, a small ... to fan bacterial growth as well as ... this infection process. Their findings appear in a ...
Breaking Biology News(10 mins):Controlling contamination in open algae ponds for biofuels 2Study identifies novel genomic changes in the most common type of lung cancer 2Study identifies novel genomic changes in the most common type of lung cancer 3Bacteria hijack plentiful iron supply source to flourish 2
... American Societies for Experimental Biology (FASEB) announces the opening ... DNA in Mammalian Genomes. Mobile elements have been ... and altering functions within mammalian genomes, and continue to ... explosion of data from high throughput sources, as well ...
... prepared a patient to inhale a panic-inducing dose of carbon ... the mixture, she cried for help, overwhelmed by the sensation ... her 40s known as SM, has an extremely rare condition ... amygdala, an almond-shaped area in the brain long known for ...
... for Experimental Biology (FASEB) announces the opening of registration ... and Flagella. The 2013 Biology of Cilia ... conference where basic and translational research intersect to drive ... ciliopathies. The underlying theme of the 2013 conference is ...
Cached Biology News:Human brain is divided on fear and panic 2Human brain is divided on fear and panic 3
(Date:1/14/2014)... As pet owners drew up their lists of New Year,s ... better care of my furry companion." Nowadays there are pet salons, ... cases to take the little canine or feline darlings along wherever ... buy some pricey toys at the pet store. But anyone who ...
(Date:1/14/2014)... The largest international professional organization of scientists ... derivatives thereof has endorsed an educational program that ... challenges of adulterated herb and botanical products. ... The Society for Medicinal Plant and Natural Product ...
(Date:1/14/2014)... 14, 2014 iLab Solutions, the leader in ... new Director of Product Strategy. In this role, Michelle will ... sub-teams to guide in the development of iLab products. Her ... maximum possible benefit to the scientific community by offering the ...
(Date:1/14/2014)... 2014  RXi Pharmaceuticals Corporation (OTCQX: RXII), a biotechnology ... therapies addressing major unmet medical needs using RNA-targeted ... of Allowance from the United States Patent and ... (sd-rxRNA®), for the treatment of fibrosis. The patent ...
Breaking Biology Technology:New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3
... ... information company that develops and supplies irrigation management solutions. The company was approved for ... irrigation management control where “the plant is the sensor™.” , ... (Vocus) April 30, 2010 -- ...
... BEACH, California , and AMSTERDAM , April ... Meeting of the American Society of Breast,Surgeons, Agendia, a ... Research and Treatment has published an important study,demonstrating the ... breast cancer recurrence according to the MammaPrint test. The,ASBS ...
... April 29  Scotland will showcase the ... the world,s leading pharma and biotech companies to its ... in Chicago .  Heading into the conference, ... the nation,s unique integrated industry approach will continue to ...
Cached Biology Technology:$250,000 Awarded to Smartfield, Inc. of Lubbock, TX by the Texas Emerging Technology Fund 2New Study Demonstrates Patients With High-Risk MammaPrint Profile Benefit From Chemotherapy 2New Study Demonstrates Patients With High-Risk MammaPrint Profile Benefit From Chemotherapy 3Scotland Announces New Life Science Leadership and Investments at BIO 2010 2Scotland Announces New Life Science Leadership and Investments at BIO 2010 3Scotland Announces New Life Science Leadership and Investments at BIO 2010 4
... that retain stiffness in liquids, protect against ... on each strip have chemically bonded dyes; ... provide clear comparison. Full-range strips (0 to ... of 100; each strip is approximately 1/4 ...
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble...
This kit only detects beta-galactosidase activity at pH 6 in cultured cells andtissue sections. Beta-galactosidase activity at pH 6 ispresent only in senescent cells, and is not found inpresenescent...
... Since the Flp-In System creates isogenic ... equivalent levels of the protein of ... in Figure 3. In this experiment ... (CAT) was subcloned into pcDNA5/FRT and ...
Biology Products: