Navigation Links
Scientists isolate cancer stem cells
Date:9/11/2008

OKLAHOMA CITY After years of working toward this goal, scientists at the OU Cancer Institute have found a way to isolate cancer stem cells in tumors so they can target the cells and kill them, keeping cancer from returning.

A research team at the University of Oklahoma led by Courtney Houchen, M.D., and Shrikant Anant, Ph.D., discovered that a particular protein only appears in stem cells. Until now, researchers knew of proteins that appeared in both regular cancer cells and stem cells, but none that just identified a stem cell.

The group has already begun work to use the protein as a target for a new compound that once developed would kill the stem cells and kill the cancer. By targeting the stem cells, scientists and physicians also would be able to stop the cancer from returning.

Houchen and Anant are focusing on adult cancer stem cells because of the major role they play in the start of cancer, the growth of cancer, the spread of cancer and the return of cancer.

Current therapies generally do not target stem cells in tumors. This allows stem cells to wait until after chemotherapy or radiation treatments to begin dividing. Researchers believe these stem cells are often responsible for the return of cancer after treatment. The identification of the stem cell marker enables researchers to develop new therapeutics that can target these cells.

Adult stem cells work as essential building blocks in organs by replenishing dying cells and regenerating damaged tissues.

Researchers expect to have initial testing completed to begin the first phase of clinical trials within 5 years led by Russell Postier, M.D. The compound, if successful in human trials, is expected to be available to the public within 10 years.


'/>"/>

Contact: Diane Clay
diane-clay@ouhsc.edu
405-271-2323
University of Oklahoma
Source:Eurekalert  

Page: 1

Related biology news :

1. Scientists form alliance to develop nanotoxicology protocols
2. Scientists point to forests for carbon storage solutions
3. US Air Force technology helps scientists understand plant root function
4. Best way to treat malaria: Avoid using same drug for everyone, scientists say
5. Scientists uncover Ebola cell-invasion strategy
6. Scientists use remote satellite imaging to predict outbreaks of infectious disease
7. Scientists develop new method to investigate origin of life
8. Caltech scientists create DNA tubes with programmable sizes for nanoscale manufacturing
9. Indiana U researchers launch social networking and research management tool for scientists
10. CSHL scientists identify new drug target against virulent type of breast cancer
11. Senescence in liver cells is found by CSHL scientists to help limit acute tissue damage
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists isolate cancer stem cells
(Date:2/8/2017)... Feb. 7, 2017 The biometrics market ... the confluence of organizations, desires to better authenticate ... systems (password and challenge questions), biometrics is quickly ... systems. The market is driven by use cases, ... consumer and enterprise uses cases, with consumer-facing use ...
(Date:2/7/2017)... , Feb. 7, 2017   MedNet Solutions ... the entire spectrum of clinical research, is pleased to ... , its innovative, highly flexible and award winning ... customers. iMedNet is a proven Software-as-a-Service ... Electronic Data Capture (EDC), but also delivers an entire ...
(Date:2/7/2017)... New York , February 7, 2017 ... as ID Global Solutions Corporation [OTC: IDGS], ("Ipsidy" or ... management and electronic transaction processing services, is pleased to ... of the Company. Effective January 31, 2017, ... the Board of Directors, CEO and President.  An experienced ...
Breaking Biology News(10 mins):
(Date:2/24/2017)... China Cord Blood Corporation (NYSE: CO ) ... blood collection, laboratory testing, hematopoietic stem cell processing and ... results for the third quarter and first nine months ... Third Quarter of Fiscal 2017 Highlights ... increased by 18.6% to RMB200.9 million ($28.9 million). ...
(Date:2/24/2017)... -- VWR Corporation (NASDAQ: VWR), the leading global independent provider of ... reported its financial results for the fourth quarter and full ... 4Q16 record quarterly net sales of $1.13 billion, ... 4Q16 EMEA-APAC segment net sales ... Americas net sales increased 2.5%, or down 0.9% on an ...
(Date:2/23/2017)... 2017 ... share data, unaudited)Three Months Ended December 31,Twelve Months Ended ... $           ... 89026%Aldurazyme Net Product Revenue 3539(10)%9498(4)%Kuvan ... Product Revenue  756025%297303(2)%Vimizim Net Product ...
(Date:2/23/2017)... , Feb. 23, 2017  MIODx announced today ... two key immunotherapy technologies from the University of ... a method to monitor a patient for response ... and CTLA-4.  The second license extends the technology ... is likely to have an immune-related adverse event ...
Breaking Biology Technology: