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Scientists identify mechanism for regulating plant oil production
Date:6/8/2012

CCase activity in the test tube. Addition of the suspected slow-down signal provided independent proof that both the signal and target of the signal were correctly identified.

To establish that this feedback mechanism operates in seeds and is not just a weird quirk of the cell-culture setup, the scientists isolated developing canola embryos to test the process. "It worked precisely the same way," Shanklin said.

With the details of the oil production feedback mechanism in hand, Shanklin's team is now exploring how they might interfere with the process, including biochemical schemes to keep the "slow-down" signaling metabolite from accumulating, ways to block its effects on ACCase, and more.

"If we can interrupt this process, we hope to fool the cells so they won't be able to gauge how much oil they have made and will make more," Shanklin said.


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Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory
Source:Eurekalert

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