Navigation Links
Scientists identify an innate function of vitamin E
Date:12/20/2011

sical force of exercise tears the membrane. Vitamin E enables adequate plasma membrane repair despite the oxidant challenge and keeps the situation in check.

When he mimicked what happens with exercise by using hydrogen peroxide to produce free radicals, he found that tears in skeletal muscle cells would not heal unless pretreated with vitamin E.

Next steps, which will be aided by two recent National Institutes of Health grants, include examining membrane repair in vitamin E-deficient animals.

McNeil also wants to further examine membrane repair failure in diabetes. Former GHSU graduate student Dr. Amber C. Howard showed in a recent paper in the journal Diabetes that cells taken from animal models of types 1 and 2 diabetes have faulty repair mechanisms. Howard found high glucose was a culprit by soaking cells in a high-glucose solution for eight to 12 weeks, during which time they developed a repair defect. It's also well documented that reactive oxygen species levels are elevated in diabetes.

The Nature Communications paper showed that vitamin E treatment in an animal model of diabetes restored some membrane repair ability. Also, an analogue of the most biologically active form of vitamin E significantly reversed membrane repair deficits caused by high glucose and increased cell survival after tearing cells in culture.

Now McNeil wants to know if he can prevent the development of advanced glycation end products a sugar that high glucose adds to proteins that his lab has shown can also impede membrane repair in the animal models of diabetes. The researchers have a drug that at least in cultured animal cells, prevents repair defects from advanced glycation end products.
'/>"/>

Contact: Toni Baker
706-721-4421
Georgia Health Sciences University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Chinese scientists announce the first complete sequencing of Mongolian genome
2. Tool enables scientists to uncover patterns in vast data sets
3. Scientists discover second-oldest gene mutation
4. Scientists find microbes in lava tube living in conditions like those on Mars
5. Scientists discover why buttercups reflect yellow on chins
6. Scientists forecast crops that adapt to changing weather
7. Wheat cant stop Hessian flies, so scientists find reinforcements
8. Babies born with no eyes: Scientists identify genetic cause
9. Max Planck Florida Institute scientists create first realistic 3D reconstruction of a brain circuit
10. UCSB scientists make advances in neuroscience and vision research
11. Scientists discover how brain corrects bumps to body
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists identify an innate function of vitamin E
(Date:1/22/2015)... Fla. , Jan. 13, 2015  Today, FreeWavz ... technology, launched its crowdfunding campaign on Fundable, ... the build of production capacity to meet customer ... Photo - http://photos.prnewswire.com/prnh/20150113/168790 ...
(Date:1/22/2015)... Jan. 20, 2015 NXT-ID, Inc. (NASDAQ: NXTD and ... reports on the recent success of the Wocket™ smart wallet at CES ... smart wallet was named as one of the "11 Hot Products at ... Products Launched At CES So Far" by Newseveryday.com and "The top 10 ...
(Date:1/22/2015)... DUBLIN , Jan. 22, 2015 Research and ... the addition of the "Global Wearable Technologies ... Growth, Share, Overview, Trends and Forecast 2014-2020" ... Wearable Technologies are smart devices that can be ...
Breaking Biology News(10 mins):FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 2
... clogs waterways around the world has at least one redeeming ... and submarines. The Brazilian fern Salvinia molesta ... its surface is dotted with oddly shaped hairs that trap ... In the November 1 issue of the Journal ...
... , WASHINGTON The magnitude and depth of the ... to determine the extent and severity of ecological damage and ... of Mexico, says an interim report by the National Research ... processes -- such as fisheries production -- in addition to ...
... growing faster, suggesting that at least some forests may be ... While forests elsewhere are thinning from wildfires, insect damage ... trees in the far north of Alaska have grown more ... study has found. The health of forests globally is gaining ...
Cached Biology News:Plant with 'eggbeater' testure inspires waterproof coating 2Plant with 'eggbeater' testure inspires waterproof coating 3New report offers broad approach to assessing impacts of ecological damage 2New report offers broad approach to assessing impacts of ecological damage 3Trees on tundra's border are growing faster in a hotter climate 2Trees on tundra's border are growing faster in a hotter climate 3Trees on tundra's border are growing faster in a hotter climate 4
(Date:2/27/2015)... 2015 Bionomics Limited (ASX:BNO, ADR:BMICY) is to ... BNC105 in patients with metastatic renal cancer at the ... . The data will be presented by Dr. ... Comprehensive Cancer Center in California ... data identifies Ferritin and IL-8 as two baseline biomarkers ...
(Date:2/27/2015)... , Feb. 27, 2015  Steep Hill, the industry ... and internationally, intends to open a full service medical ... Mexico , bringing advanced scientific tools and methodology ... Steep Hill is currently the only laboratory licensed ... potency and contaminant testing in order to meet the ...
(Date:2/26/2015)... , Feb. 26, 2015  23andMe, the leading ... Kate Black as Privacy Officer and Corporate Counsel. ... state privacy laws as well as health care regulations. ... she will be responsible for reviewing, updating and enhancing ... the U.S. and abroad. She joined the company January ...
(Date:2/26/2015)... 26, 2015 Protiviti ( www.protiviti.com ), a ... the Governance Portal , designed to increase the ... (GRC) tasks across multiple business units and projects. The ... customers better align their controls with the COSO ( ... requirements. In response to client feedback, Protiviti has also ...
Breaking Biology Technology:New BNC105 Biomarker Data to be Presented at US Cancer Conference 2New BNC105 Biomarker Data to be Presented at US Cancer Conference 3New BNC105 Biomarker Data to be Presented at US Cancer Conference 4New BNC105 Biomarker Data to be Presented at US Cancer Conference 5Steep Hill First to Receive Provisional Approval to Establish Laboratory Services for Cannabis Testing in State of New Mexico 223andMe Appoints Kate Black as Privacy Officer and Corporate Counsel 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 3
... the Genetics Policy Institute  (GPI) joined the Coalition ... curiae ("friend of the court") brief in the United States ... federal funding for human embryonic stem cell research. ... District Court and in the Court of Appeals, the latter ...
... Cord Blood Corporation (NYSE: CO ) ("CCBC" ... collection, laboratory testing, hematopoietic stem cell processing, and stem ... results for the third quarter and first nine months ... Third Quarter of Fiscal 2012 Highlights ...
... a leading provider of medical IT solutions, announced the ... in One EMR/PACS/Practice Management platform at the HIMSS12 meeting ... will enable Medstreaming EMR customers to mine any EMR ... format, including DICOM. "By introducing Web ...
Cached Biology Technology:Genetics Policy Institute (GPI) Files Additional Legal Arguments in Sherley v. Sebelius Stem Cell Case 2China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 2China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 3China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 4China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 5China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 6China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 7China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 8China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 9China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 10China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 11China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 12China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 13China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 14China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 15Medstreaming Launches Web-Based Analytics for All in One EMR/PACS/Practice Management Platform at HIMSS 2Medstreaming Launches Web-Based Analytics for All in One EMR/PACS/Practice Management Platform at HIMSS 3
... The new StrepMAB-Immo coated microplates can be ... of SerAla-Strep-tag II fusion proteins for ELISA ... small amounts of such proteins are bound ... graphic on the left) and will not ...
... SPA Screening Assay, 5 x ... eliminate lengthy sample extraction procedures and ... 1.32-84.28 ng/ml (4-256 pmol/ml).Sensitivity: 0.65 ng/ml ... C. Category: Drug Screening & Cellular ...
...
Request Info...
Biology Products: