Navigation Links
Scientists form alliance to develop nanotoxicology protocols
Date:9/9/2008

ZRICH, Switzerland -- Sept. 9, 2008 -- A team of materials scientists and toxicologists announced the formation of a new international research alliance to establish protocols for reproducible toxicological testing of nanomaterials in both cultured cells and animals. The International Alliance for NanoEHS Harmonization (IANH) was unveiled today at Nanotox 2008, one of the world's largest biennial nanotoxicological research meetings.

"When this team of scientists from Europe, the U.S., and Japan are able to get the same results for interactions of nanomaterials with biological organisms, then science and society can have higher confidence in the safety of these materials," said Kenneth Dawson, of University College Dublin and current chair of the IANH team.

Nanotechnology provides the opportunity for enabling new products that could meet a wide range of societal needs, but concerns over potential environmental, health and safety impacts of these materials may limit their adoption. Multiple organizations including the Organization for Economic Co-operation and Development (OECD) and the International Nanotechnology Conference for Communication and Cooperation (INC) have highlighted the importance of international collaboration to accelerate understanding of nanotechnology implications for society. This alliance, IANH, was established by leading materials and toxicological researchers to address this need.

Although Andrew Maynard, a leading scientist in this area, is not a member of this alliance, he sees the need for this effort. "This initiative is a major step toward ensuring hazard evaluations of emerging nanomaterials that are both relevant and reproducible," said Andrew Maynard, Chief Scientist, Project on Emerging Nanotechnologies, Woodrow Wilson International Center for Scholars in Washington, D.C.

The IANH team includes researchers from Germany: Wolfgang Kreyling of Helmholtz Institute; from Ireland: Kenneth Dawson of University College Dublin; from Japan: Gaku Ichihara of Nagoya University, and Kun'ichi Miyazawa of the National Institute for Materials Science; from Switzerland: Harald Krug of the Swiss Federal Laboratories for Materials Testing and Research (EMPA); from the United Kingdom: Vicki Stone of Napier University; from the United States of America: Vince Castranova, Mark Hoover, Dale Porter, and Aleksandr Stefaniak of the National Institute for Occupational Safety and Health at the Centers for Disease Control and Prevention; Vicki Colvin of Rice University; Fred Klaessig; Andre' Nel of the University of California at Los Angeles; Gnter Oberdrster and Alison Elder of the University of Rochester; and Mark Wiesner of Duke University.

Others collaborating with this alliance include from the European Union Joint Research Centre: Gert Roebben and Hendrik Emons of the Institute for Reference Materials and Measurements. From the United States of America, Vince Hackley of the National Institute of Standards and Technology; and Scott McNeil of the Nanotechnology Characterization Laboratory at the National Cancer Institute are also collaborating with the alliance.

Previous studies have identified key gaps in scientific knowledge regarding the biological interactions with nanoparticles and subsequent toxicological responses. Progress in resolving these issues is limited by the lack of testing protocols that enable reproducible assessment of the biological interactions of nanoparticles with cells and animals, and the lack of correlations between interactions observed in cells and in animals. IANH is being formed to establish testing protocols that enable reproducible toxicological testing of nanomaterials at the cell and animal levels and to start developing correlations between these two systems.

IANH members have agreed to develop specific tools and testing protocols and to perform a set of round robin experiments to lay the foundation for reproducible testing of nanomaterial biological interactions and toxicology. The alliance will establish protocols that can be shared with other researchers and foster experiments to evaluate correlations between in vitro testing and toxicological interactions in mammals and aquatic animals. These reproducible nano-biological testing protocols should enable better assessment of potential biological interactions of nanomaterials and improve correlations between in vitro testing and outcomes in animals, humans and the environment.


'/>"/>

Contact: Vicki Colvin
colvin@rice.edu
713-348-5741
Rice University
Source:Eurekalert

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/14/2016)... Florida , March 14, 2016 ... the growing mobile commerce market, announces the airing of a ... channels starting the week of March 21 st .  The ... CNBC, including its popular Squawk on the Street show. ... focused on the growing mobile commerce market, announces the airing ...
(Date:3/10/2016)... , March 10, 2016 ... new market research report "Identity and Access Management Market ... Audit, Compliance, and Governance), by Organization Size, by Deployment, ... 2020", published by MarketsandMarkets, The market is estimated to ... 12.78 Billion by 2020, at a Compound Annual Growth ...
(Date:3/9/2016)... , March 9, 2016  Crossmatch ® , ... enrollment solutions, today announced the addition of smart ... Altus multi-factor authentication platform. New contextual and ... to step-up security where it,s needed most — ... Washington, DC . --> ...
Breaking Biology News(10 mins):
(Date:5/24/2016)... , ... May 24, 2016 , ... ... diabetes, and traumatic injuries, will be accelerated by research at Worcester Polytechnic Institute ... engines of wound healing and tissue regeneration. , The novel method, developed by ...
(Date:5/24/2016)... Jolla, CA (PRWEB) , ... May 24, 2016 , ... ... financial planning for corporate executives and entrepreneurs, held The Future of San Diego Life ... in the San Diego life science community attended the event with speakers Dr. Rich ...
(Date:5/23/2016)... (PRWEB) , ... May 23, 2016 , ... The need for blood donations in South ... week by the South Texas Blood & Tissue Center, blood donations are on the decline. ... years, and they are down 21 percent in South Texas in the last four years ...
(Date:5/23/2016)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), a ... of Directors has approved the payment of a quarterly cash ... The cash dividend of $0.24 per share will ... of record as of the close of business on June ... of the Board of Directors and may be adjusted as ...
Breaking Biology Technology: