Navigation Links
Scientists find direct line from development to growth
Date:6/30/2010

DURHAM, N.C. -- It may seem intuitive that growth and development somehow go together so that plants and animals end up with the right number of cells in all the right places. But it is only now that scientists at the Duke Institute for Genome Sciences & Policy have gotten some of the first insights into how this critical coordination actually works in a plant.

The answer is surprisingly simple.

A well-known developmental protein called Short-root has been found to directly control the activity, in both time and space, of other well-known genes involved in cell division.

"It's a remarkably straightforward answer," said Philip Benfey, director of the IGSP's Center for Systems Biology. "Considering the level of complexity that is so often found in biology, this is simplicity itself."

The researchers report their findings on July 1 in the journal Nature.

Benfey's group and others have studied the molecular-level events that determine what particular cells in Arabidopsis plants will become in considerable detail. Those events involve genetic partners Short-root and Scarecrow along with a couple of microRNAs (see http://www.dukenews.duke.edu/2007/04/short-root._print.ht and http://genome.duke.edu/press/news/04-21-2010/index.php).

Researchers also have a pretty good understanding of the intrinsic factors that allow cells to go through their cycle and divide into two daughter cells. "What was missing was a connection between the two," said Rosangela Sozzani, a postdoctoral researcher in Benfey's lab and first author of the new study.

To shed light on that connection, Sozzani and her collaborators combined a number of experimental techniques and technologies to produce a dynamic, genome-wide view of the genetic events that Short-root and its partner Scarecrow set into motion within a single type of cell. At the very same time that cells divide, Short-root and Scarecrow switch on the gene cyclin D6, they report. Cyclin D6 is one of a family of genes that govern cell growth and division.

Benfey says the discovery in plants has immediate practical relevance given the central role of plants to human life, in the form of "food, feed, fuel and fiber." It's also likely that the "logic" behind plants' growth and development will carry over to other species, perhaps even our own. In fact, he and Sozzani note, animals including humans have cyclin D6 too.

"It's not just molecules," Benfey said. "There are evolutionary relationships. Once these fundamental processes got worked out, they are likely to have been kept around."


'/>"/>

Contact: Kendall Morgan
kendall.morgan@duke.edu
919-684-2850
Duke University
Source:Eurekalert

Related biology news :

1. UM School of Medicine scientists develop new strategy that may improve cognition
2. Honey as an antibiotic: Scientists identify a secret ingredient in honey that kills bacteria
3. NOAA-supported scientists predict larger than average Gulf dead zone
4. SAGE to publish the Bulletin of the Atomic Scientists
5. Scientists call on US to stem ecological impact of trade in coral reef wildlife
6. 12 women scientists announced as winners of Elsevier Foundation TWOWS Awards
7. Climate change scientists turn up the heat in Alaska
8. Scientists question EPA estimates of greenhouse gas emissions
9. Scientists create 3-D models of whole mouse organs
10. American team of scientists help protect Guatemalas Lake Atitlan
11. Underwater gliders may change how scientists track fish
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2016)... DUBLIN , Jan. 22, 2016 /PRNewswire/ ... announced the addition of the "Global ... report to their offering. --> ... of the "Global Biometrics Market in ... offering. --> Research and ...
(Date:1/20/2016)... LONDON , Jan. 20, 2016 A ... positioned to directly benefit from the explosion in genomics ... from Howe Sound Research. A range of dynamic trends ... ...... - personalized medicine - pharmacogenomics - pathogen ... economies with large markets - greater understanding of the ...
(Date:1/20/2016)... , Jan. 20, 2016  Synaptics Incorporated (NASDAQ: ... interface solutions, today announced sampling of S1423, its ... wearables and small screen applications including smartwatches, fitness ... Supporting round and rectangular shapes, as well as ... performance with moisture on screen, while wearing gloves, ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... ATLANTA , Feb. 11, 2016  Wellcentive ... a Portland, Oregon -based community ... to provide population health analytics, quality reporting and ... help FamilyCare strengthen its team of quality managers, ... reporting to the provider groups serving FamilyCare members. ...
(Date:2/11/2016)... BioInformant announces the February 2016 release of its ... and Technologies – Market Size, Segments, Trends, and Projections ... The first and only market research firm ... more than a decade of historical information on all ... type. This powerful 175 page global strategic report contains ...
(Date:2/10/2016)... /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ), a ... Mitsui & Co. Ltd., its partner in the ... investing an additional CDN$25 million in the joint venture ... 30% to 40%.  Mitsui will also play a stronger ... Sarnia , providing dedicated resources alongside ...
(Date:2/10/2016)... is introducing a hybrid membership model which will provide ... joining or renewing through an organizational purchasing model. For ... employee in any size association or AMC office can ... benefits.   John H. Graham, IV , ... organizations of any size and their employees to gain ...
Breaking Biology Technology: