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Scientists find a key element of lupus, suggesting better drug targets
Date:2/4/2013

rmacologic inhibitors of type I interferon production, and in particular, inhibitors of SLC15A4," said Theofilopoulos.

Emerging evidence indicates that TLR-based detection of self-molecules and production of interferons contribute to other autoimmune conditions, too. Thus, inhibitors of these specific immune signaling pathways might have use beyond the treatment of lupus. "We think that our findings have implications for rheumatoid arthritis, diabetes, neuroinflammatory diseases and many other diseases in which TLRs appear to play a role," Theofilopoulos said.


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Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Source:Eurekalert  

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