Navigation Links
Scientists discover genes linking puberty timing to body fat in women
Date:11/21/2010

Researchers at King's College London's Department of Twin Research have discovered, as part of a large international consortium, 30 new genes that control the age of sexual maturation in women, the Journal Nature Genetics publishes today.

Many of these genes are also known to act on body weight regulation or biological pathways related to fat metabolism. This large new study of more than 100,000 women from Europe, US and Australia highlights several specific genetic links between early puberty and body fat.

Puberty in women normally occurs between 11 14 years of age. If a child reaches a particular weight (around 45 kg), the onset of puberty is triggered. The heavier the child, the earlier puberty occurs, possibly affecting risk of later disease.

The study also found genes involved in hormone regulation, cell development and other mechanisms linked to age at menarche (the onset of menstrual periods in women), and this shows that puberty timing is controlled by a complex range of biological processes.

Massimo Mangino, author from the Twin Research Department at King's, says: 'It is fascinating how common genetic variants influence both early puberty and weight gain. The findings give us clues on how intricately linked are different biological processes.'

Professor Tim Spector, Director of Twins UK cohort said: 'This study shows the power of large genetic collaborations allowing us great insights into how puberty is triggered by precise amounts of body fat. Twin pairs are very similar for both puberty and body fat.'


'/>"/>

Contact: Emma Reynolds
emma.reynolds@kcl.ac.uk
020-784-84334
King's College London
Source:Eurekalert

Page: 1

Related biology news :

1. Bacteria use toxic darts to disable each other, according to UCSB scientists
2. Scientists question indicator of fisheries health, evidence for fishing down food webs
3. Scientists learn more about how kidneys fail and how new drugs may intervene
4. Scripps Research scientists identify new mechanism regulating daily biological rhythms
5. Caltech scientists describe the delicate balance in the brain that controls fear
6. UNC scientists identify cellular communicators for cancer virus
7. Scientists discover how the songbirds brain controls timing during singing
8. Scientists pinpoint key defense against parasite infection
9. McMaster scientists turn skin into blood
10. Scientists at IRB Barcelona discover a new protein critical for mitochondria
11. Scientists find that evergreen agriculture boosts crop yields
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/28/2017)... February 28, 2017 News solutions for biometrics, ... ... from 14 to 16 March, Materna will present its ... how seamless travel is a real benefit for passengers. To ... to their passenger touch point solutions to take passengers through the ...
(Date:2/27/2017)... --  Strategic Cyber Ventures , the industry,s first cybersecurity ... million investment in  Polarity , the first commercial human ... based and is led by cybersecurity veterans Tom ... Gula , also a longtime cybersecurity veteran and founder ... A round of funding. This new funding will be ...
(Date:2/24/2017)... , Feb. 24, 2017  EyeLock LLC, a leader of ... elite iris biometric solution on the latest Qualcomm® ... at Mobile World Congress 2017 (February 27 ... in Hall 3, Stand 3E10. ... Haven™ security platform—a combination of hardware, software ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... 28, 2017 /PRNewswire/ -RepliCel Life Sciences Inc. (OTCQB: REPCF) (TSXV: ... compelling safety and clinical data from its phase 1/2 tendon ... hair follicle-derived fibroblasts (RCT-01) as a treatment for Achilles tendinosis. ... ... safety profile at 6 months and showed no serious adverse ...
(Date:3/27/2017)... N.J. , March 27, 2017 Roka Bioscience, ... advanced testing solutions for the detection of foodborne pathogens,  today ... the Sidoti & Company Spring 2017 Convention on March 29 ... New York Marriott Marquis. About Roka Bioscience ... ...
(Date:3/27/2017)... ... March 27, 2017 , ... Biopsies from non-small cell lung ... limited tumor content in a large background of normal or wild type cells. ... for reliable detection of low abundance somatic mutations, particularly in small specimens with ...
(Date:3/27/2017)... 2017  Perthera,s Chief Bioinformatics Officer and research faculty ... , Ph.D., will be speaking at the American Medical ... March 27, 2017, she will be speaking on the ... Research and Care" (from 10:30 a.m. – 12:00 p.m. ... be a participant in the "Making Precision Oncology Data ...
Breaking Biology Technology: