Navigation Links
Scientists discover genes linking puberty timing to body fat in women
Date:11/21/2010

Researchers at King's College London's Department of Twin Research have discovered, as part of a large international consortium, 30 new genes that control the age of sexual maturation in women, the Journal Nature Genetics publishes today.

Many of these genes are also known to act on body weight regulation or biological pathways related to fat metabolism. This large new study of more than 100,000 women from Europe, US and Australia highlights several specific genetic links between early puberty and body fat.

Puberty in women normally occurs between 11 14 years of age. If a child reaches a particular weight (around 45 kg), the onset of puberty is triggered. The heavier the child, the earlier puberty occurs, possibly affecting risk of later disease.

The study also found genes involved in hormone regulation, cell development and other mechanisms linked to age at menarche (the onset of menstrual periods in women), and this shows that puberty timing is controlled by a complex range of biological processes.

Massimo Mangino, author from the Twin Research Department at King's, says: 'It is fascinating how common genetic variants influence both early puberty and weight gain. The findings give us clues on how intricately linked are different biological processes.'

Professor Tim Spector, Director of Twins UK cohort said: 'This study shows the power of large genetic collaborations allowing us great insights into how puberty is triggered by precise amounts of body fat. Twin pairs are very similar for both puberty and body fat.'


'/>"/>

Contact: Emma Reynolds
emma.reynolds@kcl.ac.uk
020-784-84334
King's College London
Source:Eurekalert

Page: 1

Related biology news :

1. Bacteria use toxic darts to disable each other, according to UCSB scientists
2. Scientists question indicator of fisheries health, evidence for fishing down food webs
3. Scientists learn more about how kidneys fail and how new drugs may intervene
4. Scripps Research scientists identify new mechanism regulating daily biological rhythms
5. Caltech scientists describe the delicate balance in the brain that controls fear
6. UNC scientists identify cellular communicators for cancer virus
7. Scientists discover how the songbirds brain controls timing during singing
8. Scientists pinpoint key defense against parasite infection
9. McMaster scientists turn skin into blood
10. Scientists at IRB Barcelona discover a new protein critical for mitochondria
11. Scientists find that evergreen agriculture boosts crop yields
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... patient care by providing unparalleled technology to leaders of the medical imaging industry.  As ... added to the range of products distributed by Ampronix. Photo - ... ... ... ...
(Date:5/3/2016)... , May 3, 2016  Neurotechnology, a ... the MegaMatcher Automated Biometric Identification System (ABIS) ... large-scale multi-biometric projects. MegaMatcher ABIS can process multiple ... using any combination of fingerprint, face or iris ... MegaMatcher SDK and MegaMatcher Accelerator , ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... Rolf ... join the faculty of the University of North Carolina Kenan-Flagler Business School ... and entrepreneurship at UNC Kenan-Flagler, with a focus on the school’s international efforts, ...
(Date:6/24/2016)... Epic Sciences unveiled a liquid biopsy ... PARP inhibitors by targeting homologous recombination deficiency (HRD) ... test has already been incorporated into numerous clinical ... Over 230 clinical trials are investigating ... PARP, ATM, ATR, DNA-PK and WEE-1. Drugs targeting ...
(Date:6/23/2016)... ... June 23, 2016 , ... UAS LifeSciences, ... launch of their brand, UP4™ Probiotics, into Target stores nationwide. The company, which ... to add Target to its list of well-respected retailers. This list includes such ...
(Date:6/23/2016)... -- Houston Methodist Willowbrook Hospital has signed a ... serve as their official health care provider. As ... provide sponsorship support, athletic training services, and most ... athletes and families. "We are excited ... to bring Houston Methodist quality services and programs ...
Breaking Biology Technology: