Navigation Links
Scientists discover first gonorrhea strain resistant to all available antibiotics
Date:7/10/2011

An international research team has discovered a strain of gonorrhea resistant to all currently available antibiotics. This new strain is likely to transform a common and once easily treatable infection into a global threat to public health. The details of the discovery made by Dr. Magnus Unemo, Dr. Makoto Ohnishi, and colleagues will be presented at the 19th conference of the International Society for Sexually Transmitted Disease Research (ISSTDR) which runs July 10-13 in Quebec City, Canada.

The team of researchers successfully identified a heretofore unknown variant of the bacterium that causes gonorrhea, Neisseria gonorrhoeae. Analyzing this new strain, dubbed H041, allowed researchers to identify the genetic mutations responsible for the bacterium's extreme resistance to all cephalosporin-class antibioticsthe last remaining drugs still effective in treating gonorrhea.

"This is both an alarming and a predictable discovery," noted Dr. Unemo of the Swedish Reference Laboratory for Pathogenic Neisseria. "Since antibiotics became the standard treatment for gonorrhea in the 1940s, this bacterium has shown a remarkable capacity to develop resistance mechanisms to all drugs introduced to control it."

"While it is still too early to assess if this new strain has become widespread, the history of newly emergent resistance in the bacterium suggests that it may spread rapidly unless new drugs and effective treatment programs are developed," Dr. Unemo continued.

Gonorrhea is one of the most common sexually transmitted diseases in the world. In the U.S. alone, according to the Center for Disease Control and Prevention (CDC), the number of cases is estimated at 700,000 annually.

Gonorrhea is asymptomatic in about 50% of infected women and approximately 2-5% of men. When symptomatic, it is characterized by a burning sensation when urinating and pus discharge from the genitals. If left untreated, gonorrhea can lead to serious and irreversible health complications in both women and men.

In women, the infection can cause chronic pelvic pain and ectopic pregnancy. It can lead to infertility, mostly in women but also in men, and it increases the risk of HIV transmission. In 3-4% of cases, untreated infections spread to the skin, blood, joints, or even the heart and can cause potentially mortal lesions. Babies born of infected mothers are at high risk of developing serious blood and joint infections, and passage through the birth canal of an infected mother can cause blindness in the infant.


'/>"/>

Contact: Jean-Franois Hupp
jean-francois.huppe@dc.ulaval.ca
418-656-7785
Universit Laval
Source:Eurekalert

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientists identify novel inhibitor of human microRNA
3. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
4. MU scientists go green with gold, distribute environmentally friendly nanoparticles
5. Scientists identify gene that may contribute to improved rice yield
6. Scientists discover why a mothers high-fat diet contributes to obesity in her children
7. MU scientists see how HIV matures into an infection
8. Earth scientists keep an eye on Texas
9. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
10. Scientists identify a molecule that coordinates the movement of cells
11. Scientists Find new migratory patterns for Mediterranean and Western Atlantic bluefin tuna
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2016)... India and LONDON ... Infosys Finacle, part of EdgeVerve Systems, a product ... and Onegini today announced a partnership to integrate ... solutions.      (Logo: http://photos.prnewswire.com/prnh/20151104/283829LOGO ... to provide their customers enhanced security to access ...
(Date:4/15/2016)... 2016 Research and Markets has ... Market 2016-2020,"  report to their offering.  , ... ,The global gait biometrics market is expected to ... period 2016-2020. Gait analysis generates multiple ... used to compute factors that are not or ...
(Date:3/31/2016)... PROVIDENCE, R.I. , March 31, 2016  Genomics ... leadership of founding CEO, Barrett Bready , M.D., ... addition, members of the original technical leadership team, including ... Vice President of Product Development, Steve Nurnberg and Vice ... have returned to the company. Dr. Bready ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute approval ... of microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory ...
(Date:6/23/2016)... 2016   EpiBiome , a precision microbiome engineering ... debt financing from Silicon Valley Bank (SVB). The financing ... advance its drug development efforts, as well as purchase ... "SVB has been an incredible strategic partner to us ... bank would provide," said Dr. Aeron Tynes Hammack ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... In a ... Hospital in Denmark detail how a patient who developed lymphedema after being treated for ... The results could change the paradigm for dealing with this debilitating, frequent side effect ...
(Date:6/23/2016)... 23, 2016 Andrew ... http://doi.org/10.17925/OHR.2016.12.01.22 Published recently in ... journal from touchONCOLOGY, Andrew D Zelenetz , ... cancer care is placing an increasing burden on ... biologic therapies. With the patents on many biologics ...
Breaking Biology Technology: