Navigation Links
Scientists discover cause of rare skin cancer that heals itself
Date:3/10/2011

he cell machinery more selectively in cancer therapy."

About TGFBR1 and MSSE

The TGFBR1 (Transforming Growth Factor (Beta), Receptor 1) gene makes a receptor protein through which healthy cells receive messages from their neighbours, instructing them to carry out processes essential to normal growth and development. Normally, TGFBR1 messages help block the growth of early tumours of various types. But cancer cells can interpret these messages very differently. For cancers that have managed to start growing, TGFBR1 actually promotes their growth and spread instead.

Interestingly, the reverse happens in the self-healing tumours that have an inherited fault in the TGFBR1 gene. MSSE patients with faulty TGFBR1 develop lots of small tumours but at some point there is a switch in behaviour and the tumours lacking TGFBR1 start to shrink and heal by themselves. Scientists do not yet fully understand how this happens but the result of this study has raised new approaches to studying this important signalling system and its relation to cancer.

MSSE is an extremely rare disease, with only a handful of new cases diagnosed each year. International translational collaborations between doctors and scientists, like the one underlying this study, are critical to allow for scientific breakthroughs to be made that could lead to possible cancer therapy.


'/>"/>

Contact: Chang Kai Chen
chang_kai_chen@a-star.edu.sg
656-826-6442
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

Page: 1 2

Related biology news :

1. USDA and Russian scientists develop high-tech crop map
2. Now, the story can be told - how scientists helped ID Amerithrax
3. Rockefeller Scientists discover new compound that rids cells of Alzheimer protein debris
4. Scripps Research scientists develop new test for pluripotent stem cells
5. Scripps Research scientists create cell assembly line
6. Scientists identify susceptibility factor for bipolar disorder
7. Scientists study control of invasive tree in western US
8. Flood-tolerant rice plants can also survive drought, say UC Riverside scientists
9. For first time, scientists show an HIV vaccine impacts the genetic makeup of the virus
10. Scientists discover genetic switch that increases muscle blood supply
11. Signaling path in brain may prevent that Im full message, UT Southwestern scientists discover
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... called TX Invasives is now available from the Lady ... at Austin for identifying harmful non-native plant, insect and ... the United States cause about $137 billion in economic ... clog waterways, kill native plants and more. , "By ... reporting where invasive species occur, we,re more likely to ...
(Date:8/28/2014)... are healthier for your neighbors than traditional cigarettes, ... to a new study from USC. , Scientists ... 10-fold decrease in exposure to harmful particles, with ... exposure to some harmful metals in second-hand e-cigarette ... While tobacco smoke contains high levels of polycyclic ...
(Date:8/28/2014)... groups and clinicians is critical to the development ... of Georgia research. , A qualitative study of ... that role models for successful breastfeeding help positively ... "Mothers who received that support are more likely ... Alex Anderson, an associate professor in the College ...
Breaking Biology News(10 mins):Mobile app makes ID of harmful plants, insects in Texas a snap 2Second-hand e-cig smoke compared to regular cigarette smoke 2Breastfeeding study shows need for effective peer counseling programs 2
... the Johns Hopkins Malaria Research Institute and their Zambian ... parasites taken from both humans and mosquitoes in rural ... high prevalence for pyrimethamine-resistance, which was consistent with the ... the region. However, parasites taken from mosquitoes themselves had ...
... also carry a particular variant of a gene run ... recent finding from the interdisciplinary research at the Department ... of Gothenburg, Sweden. Researchers in the longitudinal project ... dopamine D2 receptor gene and found that a variant ...
... international foodborne disease outbreaks and yet it is the most ... digestive tract, and a backbone of the biotech industry. ... , the American Academy of Microbiology brought together the nation,s ... frequently asked questions about this multifaceted microorganism. , "The ...
Cached Biology News:Contrasting patterns of malaria drug resistance found between humans and mosquitoes 2Report answers questions about E. coli: The good, the bad and the deadly 2
(Date:8/29/2014)... Three Lawrence Livermore researchers have received ... R&D Award for their research in producing ... , Shared with collaborators from the National Renewable ... Las Vegas (UNLV), the award recognizes the team ... production and corrosion processes. , These models have ...
(Date:8/29/2014)... Boston, MA, San Antonio, TX (PRWEB) August 29, ... audited, ISO 9001:2008 and ISO 13485:2003 certified, GAMP® ... it has been awarded an international Phase II ... patients with non-Hodgkin’s lymphoma. , Throughout this trial, ... services including, but not limited to, protocol and ...
(Date:8/28/2014)... City, Ca. (PRWEB) August 28, 2014 ... E3 rating for an alcohol-based hand sanitizer, asks food ... harvest by comparing the hand sanitizer they’re currently using ... Spray . Hand hygiene is critical to fighting cross-contamination ... environment. Best Sanitizers believes there are key criteria ...
(Date:8/28/2014)... spintronics, an electronic which is not only based ... their spin and the spin-related magnetism. Spin-charge converters ... and vice versa. Recently, the research group of ... at Johannes Gutenberg University Mainz in collaboration with ... for the first time realised a new, efficient ...
Breaking Biology Technology:Livermore Team Awarded for Hydrogen Production Research 2Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 3A new, tunable device for spintronics 2A new, tunable device for spintronics 3
... ... by Intensive Nutrition Inc., is a chewable, comprehensive multivitamin that is both sugar and ... San ... and operated manufacturer of premium dietary supplements, is proud to introduce NutriYummies, a ...
... Massachusetts-Based ... ... the leader in word of mouth (WOM) marketing campaigns for the pharmaceutical and biotechnology industry, ... strong revenue and significant year-over-year growth for its third year in a row. , ...
... Located in Amsterdam ... worldwide. Ministry of Cannabis has recently introduced 5 new strains with great medical potential. ... (PRWEB) March 26, 2010 -- ... new varieties of marijuana seeds to legal growers worldwide. Medical marijuana is ...
Cached Biology Technology:Intensive Nutrition Introduces NutriYummies, Innovative Children's Chewable Multivitamin 2HealthTalker Programs Leveraging the Power of Word of Mouth Find Huge Success for Pharmaceutical Industry 2HealthTalker Programs Leveraging the Power of Word of Mouth Find Huge Success for Pharmaceutical Industry 3Ministry of Cannabis: A Growing Collection of Medical Cannabis Seeds 2Ministry of Cannabis: A Growing Collection of Medical Cannabis Seeds 3
Mouse polyclonal antibody raised against a partial recombinant PREB. NCBI Entrez Gene ID = 10113...
Mouse monoclonal antibody raised against a partial recombinant ACTN4. NCBI Entrez Gene ID = ACTN4...
... Eppendorf Thermomixer R offers maximum application ... shaking, heating, and cooling. Its active ... application and temperature control ranges. Five ... 24 micro test tubes, are available ...
Rabbit polyclonal antibody to GluR2...
Biology Products: