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Scientists discover a molecular 'switch' in cancers of the testis and ovary
Date:7/31/2013

to improve survival rates when tumours are resistant to treatment. Having identified this 'on/off' switch, it will now be important to identify new drugs that can be used to keep it in the 'off' position."

Dr Matthew Murray, Academic Consultant in Paediatric Oncology, Addenbrooke's Hospital, Cambridge said: "The switch effect that we have discovered is present in all malignant germ cell tumours, whether they occur in males or females, young or old. Such a fundamental abnormality makes an excellent new target for treating these tumours."

Susanne Owers, Director of Fundraising at Addenbrooke's Charitable Trust, which funded this research, said: "We are delighted to have supported this study, which has identified a key protein that triggers this type of cancer. ACT funds clinical academic researchers, like Dr Murray and Prof Coleman, because they are perfectly positioned to understand the clinical problems, working closely with patients, an insight not available to all researchers. Studies like this have the potential to make a tangible difference to patients, by identifying targets for the development of new drugs which may improve survival and have less side-effects compared with standard chemotherapy treatments. By funding this research, ACT with the help of our supporters can make a powerful contribution, enabling ground breaking research to be performed."


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Contact: Genevieve Maul
gm349@admin.cam.ac.uk
44-012-237-65542
University of Cambridge
Source:Eurekalert

Page: 1 2

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