Navigation Links
Scientists devise way to sort brain cells for potential transplants
Date:7/7/2011

University of Florida scientists have discovered a way to separate the neural wheat from the chaff during the process of generating brain cells for potential patient therapies.

The technique, recently detailed in the online journal PLoS ONE, could be applied to long-awaited stem cell treatments for Parkinson's disease, spinal cord injuries and other brain disorders. It would allow doctors to deliver neurons to patients, without including vast amounts of other types of unnecessary brain cells.

"We need to be able to deliver precise doses of our therapeutic drug, which in this case is neurons that are needed to restore function lost as a result of disease or injury," said Brent A. Reynolds, Ph.D., a professor of neurosurgery with UF's Evelyn F. and William L. McKnight Brain Institute. "Prior to the development of our technology, it was not possible to deliver highly pure populations of neurons, or to control the number of neurons that were delivered."

For more than a decade, scientists and policymakers have pursued the idea of using stem cells to restore vitality in patients with brain diseases or injuries. The therapeutic stem cells can come from a variety of sources, including controversial embryonic and fetal tissue or, in this application, noncontroversial adult brain tissue.

Youthful or immature cells, neural stem cells have the ability to survive and integrate into the nervous system, but they haven't fully settled on their roles yet. Most of them will become glial cells, not the more highly valued neurons.

Experimenting with neural stem cells from rodents, UF researchers and colleagues from the Queensland Brain Institute in Australia were able to generate hearty, immature cells fully committed to becoming neurons. The accomplishment suggests it will be possible to provide unlimited quantities of neurons from a safe, renewable source of cells for replacement therapies in the central nervous system.

<
'/>"/>
Contact: John Pastor
jdpastor@ufl.edu
352-273-5815
University of Florida
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Damon Runyon Cancer Research Foundation awards prestigious fellowships to 18 top young scientists
2. Scientists sequence DNA of cancer-resistant rodent
3. Scripps Research scientists solve mystery of nerve disease genes
4. Scientists discover that Hawaii is not an evolutionary dead end for marine life
5. Scientists develop method to determine order of mutations that lead to cancer
6. USC scientists uncover mechanism by which chronic stress causes brain disease
7. UCLA stem cell scientists discover new airway stem cell
8. Johns Hopkins scientists expose cancer cells universal dark matter
9. Lithuanian scientists clean up at 2011 EUREKA Innovation Award
10. Scientists a step closer to understanding natural antifreeze molecules
11. Scientists uncover an unhealthy herds hypothesis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... Scientists at the Houston Methodist Research Institute have figured ... using a pipette -- a common laboratory tool that,s ... preliminary test results in a recent issue of the ... "Studying single cells and their unique functions has become ... faculty member Lidong Qin, Ph.D., the project,s principal investigator. ...
(Date:8/19/2014)... of fizzy soda knows that bubbles can throw tiny ... wide industrial applications, Princeton researchers have demonstrated that the ... as well. , "It is well known that bursting ... fascinated, to discover that when we covered the water ... into the water," said Howard Stone, the Donald R. ...
(Date:8/19/2014)... humans and animals in a number of ways. They ... to regrow entire organs. After being struck by lightning, ... crown. But there is one major downside to life ... the habitats in which they live and therefore completely ... this dilemma, plants have developed mechanisms that enable them ...
Breaking Biology News(10 mins):Moving single cells around -- accurately and cheaply 2Bubbling down: Discovery suggests surprising uses for common bubbles 2Bubbling down: Discovery suggests surprising uses for common bubbles 3How steroid hormones enable plants to grow 2
... ... Biometrics, ATLANTA, July ... announced today that,it has reached an agreement with TimeForge, a provider ... the terms of this agreement, TimeForge will be providing its,customers with ...
... , Researchers in Japan and Canada have discovered ... inside human cells sometimes too well. The breakthrough has ... fibrosis (CF) and some other hereditary diseases, the researchers say. ... Science . Dr. Kazahiro Nagata and colleagues at Kyoto ...
... from the human use of fossil fuels, the world,s seas ... system. The chemical balance of the sea has long been ... the sea,s surface water has gone down by 0.1, or ... a century ago. Jon Havenhand and Michael Thorndyke, researchers at ...
Cached Biology News:M2SYS Technology Selected by TimeForge to Integrate Fingerprint Software 2Researchers discover cell's 'quality control' mechanism 2Acidification of the sea hampers reproduction of marine species 2
(Date:8/18/2014)... , Aug. 18, 2014 BioElectronics ... advanced consumer medical devices said that its ... interviewed by CEOLIVE.TV as part of its ... interview is available at http://ceolive.tv/bioelectronics-corp-otc-biel/biel-videos/2282-ceolive-tv-interview-bioelectronics-corp-otcqb-biel ... explains to investors the unique advantages of ...
(Date:8/18/2014)... , August 18, 2014 ... Bioreactor Systems Market, By Application (Municipal Wastewater Treatment ... Flat Sheet and Multi Tubular), By Configuration (Internal/Submerged ... 2019", published by MarketsandMarkets, The market for membrane ... by 2019, growing at a CAGR of 15.28% ...
(Date:8/16/2014)... 2014 Firms in the ... and advisory services to businesses, government bodies and ... services are highly diverse as operators assist a ... from geological and geophysical consulting services to risk ... past five years, the recovery of the Canadian ...
(Date:8/15/2014)... 2014 Actor Robin Williams’ suicide has ... NBC’s Today Show reports, someone commits suicide every 13 ... of depression from the outside in, I contend that ... underlying cause from the inside out,” says neuroscientist Cynde ... , “Some of the accounts of Williams’ suicide have ...
Breaking Biology Technology:BioElectronics EVP Dr. Deepak Kotak Interviewed on CEO Live 2BioElectronics EVP Dr. Deepak Kotak Interviewed on CEO Live 3Membrane Bioreactor Systems Market Worth $2,927 Million by 2019 2Membrane Bioreactor Systems Market Worth $2,927 Million by 2019 3Scientific and Economic Consulting in Canada Industry Market Research Report Now Available from IBISWorld 2Scientific and Economic Consulting in Canada Industry Market Research Report Now Available from IBISWorld 3Neurofeedback Helps Alleviate the Underlying Causes of Depression 2Neurofeedback Helps Alleviate the Underlying Causes of Depression 3
... DUBLIN, Calif., April 22 SuperGen Inc.,(Nasdaq: SUPG ... and commercialization of therapies for solid tumors and,hematological malignancies, ... webcast of its 3rd Annual Analyst Day beginning at ... ET (9:00 a.m. PT) on Tuesday,April 29, 2008., ...
... to Significantly Increase Company,s ... Presence in China, ... announced today that it will build a major new research and,development ... global expansion and commitment to establishing a,long-term presence in China., ...
... Sysmex America, Inc. today,announced the successful ... studies for its integrated hematology and A1C ... Sysmex HST-N hematology,automation platform and the Bio-Rad ... automated diabetes testing in a random access,setting. ...
Cached Biology Technology:Genzyme to Build New R&D Center in Beijing 2Genzyme to Build New R&D Center in Beijing 3Genzyme to Build New R&D Center in Beijing 4Genzyme to Build New R&D Center in Beijing 5Mercy Medical Center Completes Beta Studies for Integrated Hematology and Automated Diabetes Testing Solution 2Mercy Medical Center Completes Beta Studies for Integrated Hematology and Automated Diabetes Testing Solution 3Mercy Medical Center Completes Beta Studies for Integrated Hematology and Automated Diabetes Testing Solution 4
Mouse monoclonal [N7519] to NR0B2 ( Abpromise for all tested applications). Antigen: E.coli expressed recombinant full length protein (Human) NR0B2 Entrez Gene ID: 8431 Swiss Protein ID: ...
Rabbit polyclonal to BCA1 ( Abpromise for all tested applications). Antigen: Generated using E.coli expressed mouse BCA1. Entrez GeneID: 10563 SWISS Protein ID: O43927...
PKC Sampler Kit 10 mu g each...
Purified anti-SOCS3...
Biology Products: