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Scientists design new drug type to kill lymphoma cells
Date:5/10/2010

e in protein interactions. They showed that their BCL6 inhibitor drug was specific to BCL6, and did not block other master regulatory proteins. The drug had powerful lymphoma killing activity and yet was non-toxic to normal tissues. "This is the first time a drug of this nature has been designed and it shows that it's not actually impossible to target factors like BCL6," he said.

Emerging data from other investigators suggests that BCL6 is important in many other tumor types, including forms of leukemia.

"The Samuel Waxman Cancer Research Foundation has always supported the collaborative work of scientists, funding innovative cancer research grants," said Samuel Waxman, M.D., the scientific director of the Foundation. "The Foundation has supported the work of Alexander MacKerell, Ari Melnick and Gilbert Priv for a number of years because we believe their work highlights the critical and important mission of our organizationthat collaboration can lead to potential effective cures."


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Contact: Jenny Song
jsong@waxmancancer.org
212-348-0136
Samuel Waxman Cancer Research Foundation
Source:Eurekalert

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