Navigation Links
Scientists decoding genomic sequences of H1N1 using isolates from outbreak in Argentina
Date:7/31/2009

July 30, 2009 -- Researchers at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health are working with Argentina's National Institute of Infectious Diseases, the National Administration of Laboratories and Health Institutes (ANLIS), and Roche 454 Life Sciences to decode the complete genomic sequences of influenza pandemic (H1N1) 2009 virus from patients with severe respiratory disease. The scientists will be comparing sequences of viruses associated with the current outbreak in Argentina with those found in other locations to determine if there are differences that may be linked to higher mortality rates or provide insights into virus evolution.

The Mailman School of Public Health researchers, led by Gustavo Palacios, PhD, assistant professor of Epidemiology and CII Director W. Ian Lipkin, MD, John Snow Professor of Epidemiology, and professor of Neurology and Pathology at Columbia University, plan to completely sequence up to 150 virus specimens from nasopharyngeal swabs and cultures over the next 10 days, and will share their findings with the larger scientific community. The complete sequencing of these virus specimens will allow the team to both characterize severe versus mild cases, as well as determine how the virus evolved at different points in time. Swine flu has killed 165 people in Argentina, more than any nation with the exception of the U.S. Any significant changes in the virus might influence the effectiveness of vaccines or drugs used to fight the pandemic.

"No one knows how this pandemic will evolve. Continuous surveillance will be essential to focusing both research and public health response. We are analyzing these isolates in New York and Argentina; nonetheless, we expect that members of the broader scientific community will bring new insights. Thus, our plan is to release sequences in draft form so that the vetting process can begin as soon as possible," said Dr. Lipkin.

"While there is no evidence so far to indicate the emergence of resistance to the oseltamivir vaccine, the antiviral drug that blocks the influenza virus from spreading between cells in the body, we are cautious about the findings until we have more sequences," said Gustavo Palacios, PhD. "The changes already noted in comparing the outbreak in Argentina to the U.S. haven't previously been associated with greater virulence."


'/>"/>

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health
Source:Eurekalert

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2016)... , April 15, 2016 ... "Global Gait Biometrics Market 2016-2020,"  report to their ... ) , ,The global gait biometrics market ... 13.98% during the period 2016-2020. Gait ... which can be used to compute factors that ...
(Date:3/31/2016)... , March 31, 2016   ... ("LegacyXChange" or the "Company") LegacyXChange is excited ... of its soon to be launched online site for ... https://www.youtube.com/channel/UCyTLBzmZogV1y2D6bDkBX5g ) will also provide potential shareholders a ... DNA technology to an industry that is notorious for ...
(Date:3/23/2016)... 23, 2016 ... Gesichts- und Stimmerkennung mit Passwörtern     ... MESG ), ein führender Anbieter digitaler ... mit SpeechPro zusammenarbeitet, um erstmals dessen Biometrietechnologie ... die Möglichkeit angeboten, im Rahmen mobiler Apps ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of commercial spectrophotometers and ... and the 6000i models are higher end machines that use the more unconventional z-dimension ... light beam from the bottom of the cuvette holder. , FireflySci has developed ...
(Date:6/23/2016)... ... 2016 , ... UAS LifeSciences, one of the leading manufacturers ... Probiotics, into Target stores nationwide. The company, which has been manufacturing high quality ... list of well-respected retailers. This list includes such fine stores as Whole Foods, ...
(Date:6/23/2016)... June 23, 2016 A person commits a crime, ... scene to track the criminal down. An outbreak ... and Drug Administration (FDA) uses DNA evidence to track down ... Sound far-fetched? It,s not. The FDA has increasingly used ... investigations of foodborne illnesses. Put as simply as possible, whole ...
(Date:6/23/2016)... Calif. , June 23, 2016  The Prostate Cancer Foundation ... increasingly precise treatments and faster cures for prostate cancer. Members of the Class ... across 15 countries. Read More About the Class of ... ... ...
Breaking Biology Technology: