Navigation Links
Scientists decode genome of painted turtle, revealing clues to extraordinary adaptations
Date:4/10/2013

Humans could learn a thing or two from turtles, and scientists who have just sequenced the first turtle genome uncovered clues about how people can benefit from the shelled creatures' remarkable longevity and ability to survive for months without breathing.

Understanding the natural mechanisms turtles use to protect their heart and brain from oxygen deprivation may one day improve treatments for heart attack and stroke, the researchers said.

UCLA conservation biologist and lead author Brad Shaffer collaborated with the Genome Institute at Washington University in St. Louis and 58 co-authors on the multi-year research project. Their paper, which appears in the journal Genome Biology, describes the genome of the western painted turtle, one of the most widespread and well-studied turtles in the world.

Researchers were somewhat surprised to find that the painted turtle's extraordinary adaptations were not the result of previously unknown genes but of gene networks that are common in vertebrates including humans, said Shaffer, a professor at UCLA's Institute of the Environment and Sustainability (IoES) and UCLA's Department of Ecology and Evolutionary Biology.

"They're the same genes we have, and the turtles are just using them in different ways and really cranking up their activity in most cases," said Shaffer, who also directs the La Kretz Center for California Conservation Science at the IoES.

"Given how extreme their adaptations are, I imagined we would see weird new genes, so I was surprised," he added. "But the fact that they're common means they may have direct relevance to human health conditions, especially those related to oxygen deprivation, hypothermia and possibly longevity."

Inside the turtle genome, the researchers found 19 genes in the brain and 23 in the heart that became more active in low-oxygen conditions, including one that became 130 times more active. These genes, all of w
'/>"/>

Contact: Alison Hewitt
ahewitt@support.ucla.edu
310-206-5461
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. 8 M € from EU to enhance access by scientists to the largest European biobanks
2. CSHL neuroscientists show jumping genes may contribute to aging-related brain defects
3. NYSCF scientists develop new protocol to ready induced pluripotent stem cell clinical application
4. Scientists find government justification of new environmental policy unfounded
5. NYSCF scientists develop 3-D stem cell culture technique to better understand Alzheimers disease
6. UGA discovery may allow scientists to make fuel from CO2 in the atmosphere
7. UT MD Anderson scientists uncover the nuclear life of actin
8. Scientists awarded £3M to study the way Northwest European seas absorb carbon
9. Scientists reveal quirky feature of Lyme disease bacteria
10. Scientists create new tools for battling secondhand smoke
11. Academy scientists receive top honors for long-term research and training initiatives in Mongolia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Philadelphia, PA, September 16, 2014 Schizophrenia is associated ... A growing body of research suggests that the relationship ... effort by patients to use nicotine to self-medicate symptoms ... new study, published in the current issue of ... authors found that the level of nicotine receptors in ...
(Date:9/16/2014)... are responsible for practically all vital functions in ... forward signals, transport particular substances and control immune ... proteins do not function independently of each other, ... examine the protein networks, you find many similarities ... from TUM,s Chair of Plant Systems Biology. "Some ...
(Date:9/15/2014)... microbes influence processes from digestion to disease resistance. Despite ... terrestrial ecosystems on the planet, more is known about ... Smithsonian scientists and colleagues working on Panama,s Barro Colorado ... tree were home to more than 400 different kinds ... contained more than 7,000 different kinds. , Bacteria in ...
Breaking Biology News(10 mins):Smoking and schizophrenia linked by alterations in brain nicotine signals 2Good networkers make prime targets 2Smithsonian scientists discover tropical tree microbiome in Panama 2
... flowers has been recreated by mathematicians at The University of ... the University of Cambridge to create a mathematical model of ... in flowering plants and the role it may play in ... as you alter the angle you view it from. It ...
... French and German . ... Scientists have been able to reconstruct, for the first ... tetrapods, the earliest four-legged animals. High-energy X-rays and a new ... of the 360 million year old fossils in exceptional detail ...
... quickly than the supply of honey bees, the dominant ... pollination represents a way of increasing crop yield without ... study recently published in the Proceedings of ... 2013) 1, shows that the pollination effectiveness of honey ...
Cached Biology News:How does your garden glow? 2Scientists reassemble the backbone of life with a particle accelerator 2Scientists reassemble the backbone of life with a particle accelerator 32 new studies show why biodiversity is important for pollination services in California almond 2
(Date:9/17/2014)... 17, 2014 Beckman Coulter , ... and healthcare, has renewed its agreement with Personify ... of the agreement, Personify will continue to streamline the ... on recruitment analytics, including time-to-fill, time-to-source and a deep ... agreement with Personify was based on the success of ...
(Date:9/17/2014)... Cambridge, MA (PRWEB) September 17, 2014 ... and Safety (ACRES) , a multi-stakeholder non-profit collaborative ... and efficiency in clinical research, today announced Phase ... (SASI). , Amir H. Kalali, ... Quintiles and Arti Bajpai, President, Compliance and Quality ...
(Date:9/16/2014)... emerging field of molecular electronics could take our ... the construction of tiny circuits from molecular components. ... take on the roles currently played by comparatively-bulky ... researchers from five Japanese and Taiwanese universities has ... electronics: a molecule called picene. In a paper ...
(Date:9/16/2014)... 16, 2014  Donald Fresne, President and CEO of Egenix, ... Vagner , PhD to its Scientific Advisory Committee. ... Toulouse, France , performed research at Embl (European Molecular ... Inserm, the French institute of health and medical research. He ... the Curie Institute, Orsay, France , and ...
Breaking Biology Technology:Beckman Coulter Signs 3-year RPO Contract with Personify 2Beckman Coulter Signs 3-year RPO Contract with Personify 3Global Standards Initiative for Clinical Research Sites Advances 2Global Standards Initiative for Clinical Research Sites Advances 3Global Standards Initiative for Clinical Research Sites Advances 4The future face of molecular electronics 2New Appointment to the Scientific Advisory Committee at Egenix, Inc. 2
... Oncolytics Biotech Inc. (TSX:,ONC, NASDAQ: ONCY) ("Oncolytics") ... Patent 7,374,752 entitled "Reovirus for the Treatment ... compositions,which comprise various recombinant reoviruses., "This ... protection for,reovirus compositions in the United States," ...
... of Two-Phase Examination of U.S. Asthma Control, RESEARCH ... half of adult Americans with asthma and more than ... nationally representative survey do,not have their disease well controlled, ... at the International Conference of the American,Thoracic Society meeting ...
... 20 CellCyte Genetics,Corporation (CellCyte) (OTC Bulletin ... H. Traverse, M.D., FACC, FAHA, to its ... is an interventional,cardiologist with the Minneapolis Heart ... in cardiovascular stem cell clinical,trial research., ...
Cached Biology Technology:Oncolytics Biotech Inc. Announces Issuance of 27th U.S. Patent 2Asthma Uncontrolled in More Than 40 Percent of Adults With the Disease, New Landmark Survey Shows 2Asthma Uncontrolled in More Than 40 Percent of Adults With the Disease, New Landmark Survey Shows 3CellCyte Genetics Corp. Appoints Jay H. Traverse to Scientific Advisory Board as Clinical Consultant 2CellCyte Genetics Corp. Appoints Jay H. Traverse to Scientific Advisory Board as Clinical Consultant 3
EDG-6 (1)...
...
...
... Comments: Ab-1 stains tumor cells of embryonal ... type of germ cell tumors like seminoma. Glandular ... are positive. Luminal and endocrine cells of stomach ... breast are also positive. Epitope: Carbohydrate ...
Biology Products: