Navigation Links
Scientists complete genome sequence of fungus responsible for dandruff, skin disorders
Date:11/6/2007

Scientists from P&G Beauty announced that they successfully sequenced the complete genome for Malassezia globosa (M. globosa), a naturally occurring fungus responsible for the onset of dandruff and other skin conditions in humans. Results of the genome sequencing are published in todays online edition of Proceedings of the National Academy of Sciences (PNAS). Dandruff and seborrheic dermatitis affect more than 50 percent of the human population. Despite the role of Malassezia in these and other common skin diseases, including eczema, atopic dermatitis and psoriasis, little was known about the fungus at the molecular level until this study. In addition, understanding of Malassezias genetic make-up may help scientists reevaluate the parameters that have historically been used to classify fungal organisms.

M. globosa, which is among the smallest of the sequenced free-living fungal organisms, is comprised of just around 4,285 genes roughly 300 times fewer base pairs than are found in the human genome. A common fungus that lives on the skin of humans, M. globosa feeds off of fatty external lipids. Humans naturally secrete sebum and other lipids onto the scalp, creating a prime environment for M. globosa to thrive. The average human can host to up to 10 million M. globosa. Symptoms of dandruff and seborrheic dermatitis occur when three factors come together: genetic susceptibility for an inflammatory response, the presence of sebum on the scalp and the presence of M. globosa.

"A complete genomic sequencing of a Malassezia genome opens tremendous opportunities for researchers to understand the interactions of fungi and humans," said Thomas Dawson, Ph.D., a scientist at P&G Beauty and the principal author of the PNAS study. "Its amazing that the understanding of the genetic make-up of a microscopic organism can have broad implications ranging from human health to agricultural
'/>"/>

Contact: Corrie Allen
callen@spectrumscience.com
202-955-6222
Spectrum Science Public Relations
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2015)... March 24, 2015   Crossmatch ™, a ... announced that its U.are.U ® 4500 Fingerprint ... Goorin Bros . to achieve PCI compliance for ... access to the POS terminal, protecting the retailer ... data breaches. With one-third of ...
(Date:3/23/2015)...  In the 2014 fiscal year, irs.gov recorded over ... figure accounts for a fraction of the estimated losses ... exceeds $11 billion globally. The polygraph has traditionally been ... occurred. Investor Mark Saint Juste along with ... partnered to administer the test in a new ...
(Date:3/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ) has ... Strategic Business Report" report to their offering. ... US$ Thousands. The report provides separate comprehensive analytics for the ... , Europe , Asia-Pacific ... World. Annual estimates and forecasts are provided for ...
Breaking Biology News(10 mins):Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4
... of interesting ?and potentially life-saving ?biological molecules. But tracking ... can be time-consuming, expensive and unreliable. , Now Salk ... of the rainforest and into the lab. Their findings ... journal Nature. , Stéphane Richard, Joseph Noel and Tomohisa ...
... reports ?one from Louisiana, one from Japan and ... pointing to involvement of endocannabinoids as a novel ... applications in eating, disease treatment and social behavior. ... The team from Tulane and Louisiana State Universities, ...
... to one another through the routine exchange of electrical ... the higher regions of the brain - regions that ... dialogue - apparently lose their ability to communicate effectively, ... in the journal Science, a team of researchers led ...
Cached Biology News:Stem cell training program to make its Stanford debut 2Stem cell training program to make its Stanford debut 3Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress 2Frog peptides block HIV in lab study 2Frog peptides block HIV in lab study 3
(Date:4/30/2015)... Carolina (PRWEB) May 01, 2015 Spirax ... services, is extremely proud to announce that for the ... named as a winner of a Queen’s Award for ... for the design and manufacture of a unique flowmeter. ... the revolutionary alternative to traditional steam flow measurement. ...
(Date:4/30/2015)... Cytokinetics, Incorporated (Nasdaq: CYTK) reported total research and ... million, compared to $8.0 million during the same period in ... $8.9 million, or $0.23 per basic and diluted share. This ... in 2014, of $8.7 million, or $0.27 per basic share ... equivalents and investments totaled $117.5 million. , "During the ...
(Date:4/30/2015)... April 30, 2015 Oxford Finance LLC ("Oxford"), ... life sciences and healthcare services companies, today announced the ... agreement with Celula, Inc., a diagnostic testing company focused ... better patient care and improved outcomes.  Proceeds of the ... expand the commercialization of its products in the U.S. ...
(Date:4/30/2015)... 30, 2015  The Paul G. Allen Family Foundation ... grants to six groups of researchers with projects at ... in neuroscience: growing mature human brain cells in the ... $7.5 million over three years.  "This ... is especially significant because the field of neuronal maturation ...
Breaking Biology Technology:Spirax Sarco Receives a Queen’s Award for Innovation 2Spirax Sarco Receives a Queen’s Award for Innovation 3Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 2Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 3Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 4Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 5Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 6Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 7Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 8Oxford Finance Provides $10 Million Debt Financing to Celula 2The Paul G. Allen Family Foundation Awards $7.5 Million To Study Brain Cell Growth And Development 2The Paul G. Allen Family Foundation Awards $7.5 Million To Study Brain Cell Growth And Development 3The Paul G. Allen Family Foundation Awards $7.5 Million To Study Brain Cell Growth And Development 4The Paul G. Allen Family Foundation Awards $7.5 Million To Study Brain Cell Growth And Development 5
... Participate at the "Facing ... JERUSALEM, Israel, May 6 Oramed,Pharmaceuticals, Inc. (OTCBB: ... for the first annual Presidential conference, "Facing,Tomorrow," as one ... of Israel. The monumental event is being held to ...
... May 5 NeoGenomics, Inc. (OTC,Bulletin Board: NGNM) announced today ... on Wednesday, May 7, 2008., The Company has ... results on May 7, 2008, at 11:00 AM EDT. ... at least,five minutes prior to the call. A replay ...
... (NYSE: BSX ) announced today that a ... its ruling in an,arbitration between the Company and ... to the 2005 settlement agreement between,the companies, alleged ... U.S. and European patents held by Medinol. The,arbitrators ...
Cached Biology Technology:Israel's Prestigious President's Conference to Feature Oramed Pharmaceuticals' Revolutionary Oral Insulin Capsule 2NeoGenomics Schedules Its Q1 2008 Earnings Release for May 7, 2008 2WIPO Panel Rules Boston Scientific Liberte(R) and TAXUS(R) Liberte(R) Stents Do Not Infringe Medinol Patents 2WIPO Panel Rules Boston Scientific Liberte(R) and TAXUS(R) Liberte(R) Stents Do Not Infringe Medinol Patents 3
... EKMax™ is a recombinant preparation of ... EKMax™ Enterokinase is expressed and isolated from ... highly purified enzyme preparation (2). It recognizes ... bond after the lysine residue. The enzyme ...
... (rat) - Diluted Antiserum for RIA, Host: ... U-23 (rat) Immunology Products, Host: Rabbit ... our corresponding peptide and 1 ... Neuromedin U-23 (rat) (H-9295) and ([ 1 ...
...
...
Biology Products: