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Scientists awarded carcinoid tumor and pancreatic neuroendocrine tumor research grants
Date:3/25/2011

nes and peptides secreted by the carcinoid tumor may also provide proliferative signals to the carcinoid cells, forming a positive feedback loop. The hope is that this study will reveal the nature of this positive feedback loop in carcinoid tumors and identify Epac2 as a novel target for anti-cancer therapeutics.

  • Monica Ter-Minassian, Sc.D., postdoctoral fellow, Dana-Farber Cancer Institute; postdoctoral fellow, Harvard School of Public Health

Ter-Minassian's project, Molecular Markers of Outcome in Ileal Carcinoid Tumor and Other NET, is focused on the discovery and characterization of molecular and genetic factors impacting ileal carcinoid neuroendocrine tumor patient survival. She aims to first define the prognostic significance of traditional factors, including serum biomarkers chromogranin A and alkaline phosphatase in a large, prospective cohort. She will then identify common inherited genetic variants (single nucleotide polymorphisms) associated with survival and explore potential associations between these genetic variants and treatment outcomes in metastatic patients treated with specific therapeutic agents.


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Contact: Michele Sharp
Michele.Sharp@aacr.org
267-646-0622
American Association for Cancer Research
Source:Eurekalert

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