Navigation Links
Scientists at University of Colorado Anschutz Medical Campus discover new fat cell
Date:8/2/2010

AURORA, Colo. (Aug. 2, 2010) -- As if fat weren't troublesome enough, a research team at the University of Colorado School of Medicine has discovered a new type of fat cell with potentially harmful characteristics.

The new fat cells arise from stem cells in the bone marrow that travel through the blood stream to fat tissue. They are termed bone marrow progenitor-derived adipocytes. The discovery also revealed that male and female subjects accumulate the new fat cells differently. The research also may help to explain the link between types of obesity and heart disease and other illnesses.

The findings by Dwight J. Klemm, PhD, and Susan M. Majka, PhD, are reported this week in the Proceedings of the National Academy of Science of the United States of America.

"Our results explain why the accumulation of fat in certain body locations harms health," Klemm said.

According to Majka, the research "may identify ways to prevent those adverse effects as people age or gain weight."

The body stores energy in fat either white or brown cells. But over time too much fat can cause health issues. Previously, the researchers at the University of Colorado Anschutz Medical Campus had traced certain fat cells back to bone marrow. It appeared likely that a type of stem cell (the hematopoietic cell) was getting into the blood stream and settling somewhere else.

The latest research, which used laboratory mice but applies to humans, demonstrates that is the case. It shows that these stem cells travel through the blood stream into fat tissue and tend to accumulate in deep abdominal fat, primarily of females. This new type of fat may affect the body's ability to dispose of fats and sugars, and produces inflammatory problems. The results also help explain why fat in different parts of the body behaves differently. The research team now is detailing the health threats these fat cells cause and looking for ways to halt the formation and accumulation of harmful fat.

Faculty at the University of Colorado's School of Medicine work to advance science and improve care. These faculty members include physicians, educators and scientists at University of Colorado Hospital, The Children's Hospital, Denver Health, National Jewish Health, and the Denver Veterans Affairs Medical Center. Degrees offered by the School of Medicine include doctor of medicine, doctor of physical therapy, and masters of physician assistant studies. The School is located on the Anschutz Medical Campus, one of four campuses in the University of Colorado system. For additional news and information, please visit the UC Denver newsroom online.

The University of Colorado Anschutz Medical Campus is a model for the type of interdisciplinary research in translational medicine that will take basic discovery "from the bench to the bedside."


'/>"/>

Contact: David Kelly
david.kelly@ucdenver.edu
303-503-7990
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientists identify novel inhibitor of human microRNA
3. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
4. MU scientists go green with gold, distribute environmentally friendly nanoparticles
5. Scientists identify gene that may contribute to improved rice yield
6. Scientists discover why a mothers high-fat diet contributes to obesity in her children
7. MU scientists see how HIV matures into an infection
8. Earth scientists keep an eye on Texas
9. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
10. Scientists identify a molecule that coordinates the movement of cells
11. Scientists Find new migratory patterns for Mediterranean and Western Atlantic bluefin tuna
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... , April 24, 2017 ... and partner with  Identity Strategy Partners, LLP (IdSP) ... "With or without President Trump,s March 6, 2017 ... Terrorist Entry , refugee vetting can be instilled with ... resettlement. (Right now, all refugee applications are suspended ...
(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
(Date:4/11/2017)... , April 11, 2017 No two ... researchers at the New York University Tandon School ... Engineering have found that partial similarities between prints ... used in mobile phones and other electronic devices ... The vulnerability lies in the fact that ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017 International research firm Parks ... Strategy, will speak at the TMA 2017 Annual Meeting , October ... trends in the residential home security market and how smart safety and ... Parks ... "The residential ...
(Date:10/9/2017)...  BioTech Holdings announced today identification and patenting ... stem cell therapy prevents limb loss in animal ... that treatment with ProCell resulted in more than ... to standard bone marrow stem cell administration.  Interestingly, ... of therapeutic effect.  ...
(Date:10/9/2017)... ... October 09, 2017 , ... ... October 5, 2017, in the medical journal, Epilepsia, Brain Sentinel’s SPEAC® System ... standard, video EEG, in detecting generalized tonic-clonic seizures (GTCS) using surface electromyography ...
(Date:10/6/2017)... ... October 06, 2017 , ... The ... and technology sector at their fourth annual Conference where founders, investors, innovative practitioners ... and the ELEVATE pitch competition showcasing early stage digital health and med tech ...
Breaking Biology Technology: