Navigation Links
Scientists at University of Colorado Anschutz Medical Campus discover new fat cell
Date:8/2/2010

AURORA, Colo. (Aug. 2, 2010) -- As if fat weren't troublesome enough, a research team at the University of Colorado School of Medicine has discovered a new type of fat cell with potentially harmful characteristics.

The new fat cells arise from stem cells in the bone marrow that travel through the blood stream to fat tissue. They are termed bone marrow progenitor-derived adipocytes. The discovery also revealed that male and female subjects accumulate the new fat cells differently. The research also may help to explain the link between types of obesity and heart disease and other illnesses.

The findings by Dwight J. Klemm, PhD, and Susan M. Majka, PhD, are reported this week in the Proceedings of the National Academy of Science of the United States of America.

"Our results explain why the accumulation of fat in certain body locations harms health," Klemm said.

According to Majka, the research "may identify ways to prevent those adverse effects as people age or gain weight."

The body stores energy in fat either white or brown cells. But over time too much fat can cause health issues. Previously, the researchers at the University of Colorado Anschutz Medical Campus had traced certain fat cells back to bone marrow. It appeared likely that a type of stem cell (the hematopoietic cell) was getting into the blood stream and settling somewhere else.

The latest research, which used laboratory mice but applies to humans, demonstrates that is the case. It shows that these stem cells travel through the blood stream into fat tissue and tend to accumulate in deep abdominal fat, primarily of females. This new type of fat may affect the body's ability to dispose of fats and sugars, and produces inflammatory problems. The results also help explain why fat in different parts of the body behaves differently. The research team now is detailing the health threats these fat cells cause and looking for ways to halt the formation and accumulation of harmful fat.

Faculty at the University of Colorado's School of Medicine work to advance science and improve care. These faculty members include physicians, educators and scientists at University of Colorado Hospital, The Children's Hospital, Denver Health, National Jewish Health, and the Denver Veterans Affairs Medical Center. Degrees offered by the School of Medicine include doctor of medicine, doctor of physical therapy, and masters of physician assistant studies. The School is located on the Anschutz Medical Campus, one of four campuses in the University of Colorado system. For additional news and information, please visit the UC Denver newsroom online.

The University of Colorado Anschutz Medical Campus is a model for the type of interdisciplinary research in translational medicine that will take basic discovery "from the bench to the bedside."


'/>"/>

Contact: David Kelly
david.kelly@ucdenver.edu
303-503-7990
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientists identify novel inhibitor of human microRNA
3. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
4. MU scientists go green with gold, distribute environmentally friendly nanoparticles
5. Scientists identify gene that may contribute to improved rice yield
6. Scientists discover why a mothers high-fat diet contributes to obesity in her children
7. MU scientists see how HIV matures into an infection
8. Earth scientists keep an eye on Texas
9. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
10. Scientists identify a molecule that coordinates the movement of cells
11. Scientists Find new migratory patterns for Mediterranean and Western Atlantic bluefin tuna
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2017)... Today, American Trucking Associations announced Seeing ... and eye tracking software, became the newest member ... "Artificial intelligence and advanced sensing algorithms ... driver,s attentiveness levels while on the road.  Drivers ... fatigue and prevent potential accidents, which could lead ...
(Date:5/16/2017)... -- Veratad Technologies, LLC ( www.veratad.com ), an innovative and ... solutions, announced today they will participate as a sponsor ... May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions of ... digital world, defining identity is critical to nearly every ...
(Date:4/19/2017)... , April 19, 2017 ... its vendor landscape is marked by the presence of ... is however held by five major players - 3M ... these companies accounted for nearly 61% of the global ... leading companies in the global military biometrics market boast ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... August 15, 2017 , ... Coffea arabica accounts for ... abiotic factors. During this educational webinar, participants will learn about the importance of ... a better understanding of how genomics is important for coffee breeding improvement. , ...
(Date:8/14/2017)... ... August 14, 2017 , ... The Conference Forum has ... will take place on September 6, 2017 at the Marriott Copley Place in Boston, ... Experimental Medicine, Informatics, and Regulatory Strategy, Pfizer Innovative Research Lab, Pfizer, who leads 19 ...
(Date:8/11/2017)... ... August 11, 2017 , ... ... in particular, more natural alternatives to synthetic ingredients,” said Matt Hundt, President of ... with the established manufacturing presence and know-how of Biorigin will allow us to ...
(Date:8/10/2017)... Durham, NC (PRWEB) , ... August 09, 2017 , ... ... fractures. Almost half never recover well enough to live an independent lifestyle and, even ... , A new discovery by doctors at the University of California Davis Medical ...
Breaking Biology Technology: