Navigation Links
Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
Date:4/10/2008

Inserting tiny scaffolding into the brain could dramatically reduce damage caused by strokes the UK National Stem Cell Network Annual Science Meeting will hear today (10 April). Speaking at the conference in Edinburgh, Dr Mike Modo from the Institute of Psychiatry will explain how combining scaffold microparticles with neural stem cells (NSCs) could regenerate lost brain tissue.

Strokes cause temporary loss of blood supply to the brain which results in areas of brain tissue dying - causing loss of bodily functions such as speech and movement. Neural Stem Cells offer exciting possibilities for tissue regeneration, but there are currently major limitations in delivering these cells to the brain. And while NSC transplantation has been proven to improve functional outcomes in rats with stroke damage little reduction in lesion volume has been observed.

However, with funding from the Biotechnology and Biological Sciences Research Council (BBSRC) neurobiologists from the Institute of Psychiatry (Dr Mike Modo & Prof Jack Price) and tissue engineers from the University of Nottingham (Prof Kevin Shakesheff) have joined forces to tackle the challenge of tissue loss as a result of stroke.

Working with rats, Dr Modo and his team are developing cell-scaffold combinations that could be injected into the brain to provide a framework inside the cavities caused by stroke so that the cells are held there until they can work their way to connect with surrounding healthy tissue.

Dr Modo explains: We propose that using scaffold particles could support NSCs in the cavity to re-form the lost tissue and provide a more complete functional repair. The ultimate aim is to establish if this approach can provide a more efficient and effective repair process in stroke.

The team hope their work will pave the way for NSCs to be successfully used in clinical settings to re-develop parts of the brain damaged by stroke and neurodegenerative diseases.


'/>"/>

Contact: Matt Goode
matt.goode@bbsrc.ac.uk
01-793-413-299
Biotechnology and Biological Sciences Research Council
Source:Eurekalert

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... May 3, 2016  Neurotechnology, a provider of ... MegaMatcher Automated Biometric Identification System (ABIS) , a ... projects. MegaMatcher ABIS can process multiple complex biometric ... combination of fingerprint, face or iris biometrics. It ... and MegaMatcher Accelerator , which have ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
(Date:3/31/2016)... Florida , March 31, 2016 ... ) ("LegacyXChange" or the "Company") LegacyXChange ... potential users of its soon to be launched online ... ( https://www.youtube.com/channel/UCyTLBzmZogV1y2D6bDkBX5g ) will also provide potential ... use of DNA technology to an industry that is ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... CA (PRWEB) , ... June 27, 2016 , ... ... for clinical trials, announced today the Clinical Reach Virtual Patient Encounter CONSULT ... care circle with the physician and clinical trial team. , Using the CONSULT module, ...
(Date:6/24/2016)... TOKYO , June 24, 2016  Regular discussions on ... to take place between the two entities said Poloz. ... in Ottawa , he pointed to the ... and the federal government. ... Poloz said, "Both institutions have common economic goals, why not ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... pleased to announce the launch of their brand, UP4™ Probiotics, into Target stores ... 35 years, is proud to add Target to its list of well-respected retailers. ...
(Date:6/23/2016)... ... 2016 , ... Charm Sciences, Inc. is pleased to announce ... Research Institute approval 061601. , “This is another AOAC-RI approval of the Peel ... President of Regulatory and Industrial Affairs. “The Peel Plate methods perform comparably to ...
Breaking Biology Technology: