Navigation Links
Scientists announce human intestinal stem cell 'breakthrough' for regenerative medicine
Date:9/4/2011

Human colon stem cells have been identified and grown in a lab-plate for the first time. This achievement, made by researchers of the Colorectal Cancer Lab at the Institute for Research in Biomedicine (IRB Barcelona) and published in Nature Medicine, is a crucial advance towards regenerative medicine.

Throughout life, stem cells of the colon regenerate the inner layer of our large intestine in a weekly basis. For decades scientists had evidences of the existence of these cells yet their identity remained elusive. Scientists led by the ICREA Professor and researcher at the Institute for Research in Biomedicine (IRB Barcelona) Eduard Batlle discovered the precise localization of the stem cells in the human colon and worked out a method that allows their isolation and in vitro expansion, that is their propagation in lab-plates. Growing cells outside the body generally requires providing the cells in a lab-plate with the right mix of nutrients, growth factors and hormones. But in the same way that each of the more than 200 types of cells in our body differs from the others so too do optimal growing conditions in the lab. Consequently, human adult stem cell culture in labs has been a truly impossible mission until now. Batlle's team has also established the conditions for maintain living human colon stem cells (CoSCs) outside of the human body: "This is the first time that it has been possible to grow single CoSCs in lab-plates and to derive human intestinal stem cell lines in defined conditions in a lab setting," explains the IRB Barcelona researcher Peter Jung, first author of the study together with Toshiro Sato, from the University Medical Center Utrecht in The Netherlands.

The development, published by Batlle's research group in the prestigious journal Nature Medicine, arrives after more than 10 years of intense research focused on the characterization of the biology of the intestinal stem cells and its connection with cancer. The research has
'/>"/>

Contact: Itziar Castanedo
itziar.castanedo@irbbarcelona.org
34-934-031-301
Institute for Research in Biomedicine (IRB Barcelona)
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Scientists unravel the cause of rare genetic disease: Goldman-Favre Syndrome explained
2. Hurricane Irene: Scientists collect water quality and climate change data from huge storm
3. Tropical coral could be used to create novel sunscreens for human use, say scientists
4. Scientists find new drug candidates for set of protein-folding diseases
5. Weight loss without the hunger: Cornell scientists say eat a lighter lunch
6. Scientists receive grant to develop new DNA sequencing method
7. Cars could run on recycled newspaper, Tulane scientists say
8. Scientists create natural Alzheimers-fighting compound in lab
9. Scientists reengineer antibiotic to overcome dangerous antibiotic-resistant bacteria
10. Scripps Research scientists help pinpoint cause of stress-related DNA damage
11. Penn molecular scientists develop color-changing stress sensor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/14/2014)... of researchers, led by the Chinese Academy of Agricultural ... Genetics a brief genomic history of tomato breeding, ... plant. , The C.M. Rick Tomato Genetics Resource Center ... study by providing seed of both cultivated tomato varieties ... on the first tomato genome sequence completed just two ...
(Date:10/14/2014)... Over the past decades, we have seen numerous tragic ... needs of infants for social contact and stimulation has ... , Infancy and childhood are critical life ... generation of research suggests that enriched environments, full of ... function. In contrast, deprivation and stress may compromise cortical ...
(Date:10/14/2014)... oral biologic medication has successfully treated chronic, precancerous inflammation ... study authored by an MD/PhD student in the University ... , The study is featured on the cover of ... was published online ahead of print in September. The ... Inflammatory cells in the colon, or polyps, are very ...
Breaking Biology News(10 mins):Institutional rearing may increase risk attention-deficit disorder 2Oral drug reduces formation of precancerous polyps in the colon, UB researchers find 2Oral drug reduces formation of precancerous polyps in the colon, UB researchers find 3
... When a foreign object such as a catheter enters the ... into a slick coating a biofilm that is ... cannot be defeated by a basic approach of conventional means. ... reveals the key players in the network and how they ...
... 2010 China PharmaHub Corp. (OTC Bulletin Board: ... agreement to be a distributor for Integrated Biometrics ("IB"), ...  PharmaHub will have the exclusive distribution rights in China, ... to sell IB products to customers in the Pharmaceutical, ...
... soldiers in the battlefield healthy, the U.S. Army is exploring ... Current techniques for analyzing water in the field can take ... Lipkens of Western New England College in Springfield, Massachusetts and ... They are working on an alternative technology that uses sound ...
Cached Biology News:Research provides new leads in the case against drug-resistant biofilms 2China PharmaHub Signs Distribution Agreement with Integrated Biometrics 2China PharmaHub Signs Distribution Agreement with Integrated Biometrics 3
(Date:10/19/2014)... The Asia-Pacific Speech Analytics market report ... with analysis and forecast of revenue. This market is ... $208 million by 2019, at a Compound Annual Growth ... Browse through the TOC of the Asia-Pacific Speech Analytics ... analysis provided. It also provides a glimpse of the ...
(Date:10/18/2014)... October 19, 2014 The “Human ... Acting, Intermediate Acting, Premixed), Modern Human Insulin (Rapid ... Levemir, NovoRapid, Novomix, Tresiba, Others) - Forecast to ... drivers, restraints, challenges, opportunities, current market trends, and ... with the estimates and forecasts of the revenue ...
(Date:10/18/2014)... Asia-Pacific Liquid Crystal on Silicon (LCoS) display market report ... analysis and forecast of revenue. This market was valued ... reach $380.0 million by 2018, at a CAGR of ... TOC of the Asia-Pacific LCoS display market report, to ... also provides a glimpse of the segmentation of the ...
(Date:10/18/2014)... 2014 The “Global Diagnostic Electrocardiograph ... by End-user (Hospitals, Home/Ambulatory, Research Center, Physician Office, ... -Global Forecast to 2020” provides a detailed overview ... market trends, and strategies impacting the global diagnostic ... of the revenue and share analysis. , The ...
Breaking Biology Technology:The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 2Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 3Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 5The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 3The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 2The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 3The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 4The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 5
... Approve Merger With Integra on October 11, ... ... September 5 IsoTis, Inc.,(NASDAQ: ISOT ) ("IsoTis"), an orthobiologics ... U.S. Securities and,Exchange Commission ("SEC") in connection with the IsoTis-Integra,LifeSciences Holdings ...
... WEST BRIDGEWATER, Mass., Sept. 5 Pressure,BioSciences, Inc. ... has received,approval to CE Mark the Barocycler NEP2320, ... (PCT) instrument. The,Company also announced that it has ... indicating that the Barocycler NEP2320 has been found ...
... 5 Thermo Fisher,Scientific Inc. (NYSE: TMO ... the instrument sales business of Davis Inotek Instruments, ... and excludes its,related calibration services. Davis Instruments is ... instruments, serving customers in a,wide range of industries ...
Cached Biology Technology:IsoTis Files Definitive Proxy Statement 2IsoTis Files Definitive Proxy Statement 3IsoTis Files Definitive Proxy Statement 4Pressure BioSciences, Inc. Announces CE Mark Approval and Compliance with the IEC 61010-1 Standard for a Second PCT-based Instrument, the Barocycler NEP2320 2Pressure BioSciences, Inc. Announces CE Mark Approval and Compliance with the IEC 61010-1 Standard for a Second PCT-based Instrument, the Barocycler NEP2320 3Pressure BioSciences, Inc. Announces CE Mark Approval and Compliance with the IEC 61010-1 Standard for a Second PCT-based Instrument, the Barocycler NEP2320 4Thermo Fisher Scientific Acquires Instrument Sales Business of Davis Inotek 2Thermo Fisher Scientific Acquires Instrument Sales Business of Davis Inotek 3Thermo Fisher Scientific Acquires Instrument Sales Business of Davis Inotek 4
Recombinant Equine IL-6...
dithiothreitol (DTT) Reactive Dyes and Chemicals Thiol-Reactive Dyes, Haptens and Quenchers Reducing Agents...
GRADIENT MAKER, 30 ML, 1 EA. Category: Protein Vertical Instruments....
Recombinant Rat Leptin, CF...
Biology Products: