Navigation Links
Science casts doubt on famous British murder case
Date:10/16/2007

ith Foran and Beth Wills, a genealogist from Ionia, to resolve what he saw as inconsistent evidence.

Forans laboratory specializes in ancient and forensic DNA evidence, often working with human remains that are thousands of years old. The nearly 100-year-old microscope slide, sent to Michigan State from the Royal London Hospital Archives and Museum, is the same one the pathologist Bernard Spilsbury used to help hang Crippen. In 1910, forensic pathology was more primitive;

Spilsburys testimony, identifying what he claimed was an abdominal scar consistent with Coras medical history, convinced the jury that these were Coras remains.

Crippen went to the gallows insisting he was innocent.

The present-day challenge: getting past the pine sap that sealed the slide and the formaldehyde used to preserve the tissue in order to examine the mitochondrial DNA that could identify Cora Crippen based on the genetic history of her maternal relatives.

Mitochondrial DNA is the genetic blueprint that is passed down in the egg from mother to daughter. Unlike regular DNA, which comes from the cells nucleus, Foran explained that mitochondrial DNA remains more stable in aged tissue and is easier to retrieve. Also, mitochondrial DNA remains relatively undiluted through generations, offering a reliable familial match.

Forans laboratory has devised methods to extract and isolate mitochondrial DNA. Unable to break through the sap seal, he chipped away at the slides glass cover slip to get at the tissue sample. One of his graduate students recently studied ways to work around formaldehyde fixation to isolate DNA.

The goal: compare the mitochondrial DNA in the slide that convicted Crippen with Wills assignment finding a maternal relative of Cora Crippen. If Hawley Crippen indeed killed his wife and buried some of her remains in the cellar, those remains would share specific DNA characteristics with Cora Crippens current day relat
'/>"/>

Contact: David Foran
foran@msu.edu
517-432-5439
Michigan State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site
2. Kinovate Life Sciences Launches Nittophase?High Performance Solid Support For Oligonucleatide Synthesis
3. Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences
4. Whats really making you sick? Plant pathologists offer the science behind Sick Building Syndrome
5. Science study holds implications for gene therapy and stem cell biology
6. Scientists generate patient-specific stem cells, Science study says
7. Innovative collaboration brings Arctic science into the classroom
8. TrueBlue Archive Will Store Raw Life Sciences Data for Proteomics and Drug Testing
9. Leprosy genome tells story of human migrations, French researchers report in Science
10. DOEs Office of Science sets up program to aid scientists displaced by Hurricane Katrina
11. Sciences Breakthrough of the Year: Watching evolution in action
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/16/2015)... Germany , March 16, 2015 ... Identification Systems GmbH will present groundbreaking innovations in ... Hanover, Germany .      ... DERMALOG,s latest biometric innovation is well at the ... next generation e-gate made in Germany ...
(Date:3/11/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/3p32qm/access_control ) has ... by Product, Application & By Geography - Global Forecast ... , This report predicts that the access ... 2020, with an estimated CAGR of 10.6%. ... such as contact cards & readers, contactless cards & ...
(Date:3/10/2015)... 2015  NXT-ID, Inc. (NASDAQ: NXTD ... biometric authentication company focused on the growing mobile ... has been named the "Number One Best Tech ... Rethink Modern ( http://www.rethinkmodern.com/ ) is a web ... and lifestyle that have a unique function or design.  ...
Breaking Biology News(10 mins):DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 2NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 3NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 4
... report in the journal Development ( dev.biologists.org ... of a type of cell that can make myelin, ... basic and clinical research. The cells the researchers ... myelin in the central nervous system. Myelin forms an ...
... field stations have long been home to a rich ... places for serendipitous discoveries in the biological and environmental ... issue of the journal BioScience , researchers affiliated ... Research (LTER) Network and other groups state that few ...
... as contributing to autoimmune disease, but a review appearing ... of vitamin D in patients with autoimmune disease may ... and that supplementing with vitamin D may actually exacerbate ... at the California-based non-profit Autoimmunity Research Foundation, the paper ...
Cached Biology News:Human ES cells progress slowly in myelin's direction 2Field stations foster serendipitous discoveries in environmental, biological sciences 2Field stations foster serendipitous discoveries in environmental, biological sciences 3Vitamin D may exacerbate autoimmune disease 2
(Date:3/26/2015)... Ale Gicqueau, Founder and President of Clinovo, will ... Align Technology, on “ Conducting Postmarket Registries - Rationale ... Conference and Exhibition on April 25th through April 28th ... poster presentation, Ale Gicqueau and Victor Chen will discuss ... the requirements and resources to conduct the registry, as ...
(Date:3/25/2015)... Agnition announced today that it will be featured ... the first time at 7:30 a.m. CST March 31 ... the extremely important role soil microbes perform in crop ... Catalyst™ technology that enhances soil and plant health for ... again on April 28. , A biochemist at Agnition ...
(Date:3/25/2015)... UK (PRWEB) March 25, 2015 ... uptake of smartphones have fuelled social media growth, ... being currently engaged in social networking. Insurance companies ... to communicate with clients and promote a diversity ... globe over are increasingly exploiting social networking services ...
(Date:3/25/2015)... Md. , March 25, 2015 Accelovance, ... named a finalist for "Best Contract Research Organization" at ... the World Vaccine Congress. This is ... a finalist for the award, winning for "Best Contract ... a "Highly Recommended" distinction in 2013. "We,re ...
Breaking Biology Technology:Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 2Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 3Agnition to be Featured In Upcoming Episode of American Farmer on RFD-TV 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 3Accelovance Nominated for 2015 Vaccine Industry Excellence (ViE) Awards 2
... , , , , , ... company,providing customized enzymes to the pharmaceutical, chemical, and other,industries, announced today ... from existing shareholders. , The Company ... product portfolio and to accelerate the development of international,markets. At the ...
... , This release is available in German ... display case. A white light appears out of nowhere. And ... glance. Only upon close examination does the source of the ... a pinhead, passes through thousands of infinitesimal lens structures measuring ...
... EMERYVILLE, Calif. , Feb. 2 Onyx Pharmaceuticals, ... at the 12th Annual BIO CEO & Investor Conference on ... ( 5:30 a.m. Pacific Time ).  Interested parties may access ... , http://www.onyx-pharm.com/view.cfm/32/Event-Calendar , It is recommended that listeners log ...
Cached Biology Technology:EUCODIS Bioscience Receives EUR 2 Million Cash Injection to Enlarge Product Portfolio and Develop International Markets 2EUCODIS Bioscience Receives EUR 2 Million Cash Injection to Enlarge Product Portfolio and Develop International Markets 3Nano for the senses 2Nano for the senses 3Onyx Pharmaceuticals to Present at the 12th Annual BIO CEO & Investor Conference 2
Recombinant Ovine (Sheep) Prolactin, Ultra Pure...
... HT, 1 kit. Facilitates the simple, phenol-free ... and hard tissue requiring proteinase K digestion.Each ... DNA from 50 preparations of up to ... Synthesis & Purification, Purification and Amplification of ...
... For rapid and efficient purification of DNA ... 15 minutes by gravity flow.Prepacked with Sephadex ... 0.15% Kathon CG/ICP Biocide.Available in three sizes ... (NAP-5), 1 ml (NAP-10) or 2.5 ml ...
Human ROR1 Affinity Purified Polyclonal Ab...
Biology Products: