Navigation Links
Scaling the wall of deafness
Date:4/14/2009

Despite modern medicine, one in 1,000 American babies are born deaf. The numbers increase markedly with age, with more than 50% of seniors in the United States experiencing some form of hearing loss.

But the era of the hearing aid, and shouting at aging in-laws, may soon be over. A new, landmark study by a world-renowned geneticist and hearing loss expert at Tel Aviv University has uncovered one of the root causes of deafness.

Prof. Karen Avraham of the Department of Human Molecular Genetics, Sackler School of Medicine at Tel Aviv University, has discovered that microRNAs, tiny molecules that regulate cell functions, help us hear. Found in "hair" cells of the ear, this discovery opens an entirely new window for possible treatments, and a cure for all types of deafness, age-related or genetic.

"Over the last decade, science has found that microRNAs are involved in heart disease, and in cancer, and for the first time ever, our lab shows that these tiny regulators in all our cells can cause deafness," says Prof. Avraham, whose groundbreaking work has previously discovered 4 deafness genes and novel mutations in 15 deafness genes, among 46 known ones.

Understanding the Hard of Hearing

Prof. Avraham's results published this month in the prestigious journal the Proceedings of the National Academy of Science, shows scientists an important factor that could cause deafness. It may lead to potential ways to ameliorate deafness, even in people where the hearing loss has no genetic basis, like after a major injury to the ear. Her recent study investigated mice and zebrafish, but the model holds true for all vertebrates ― including humans, she says. In separate studies in the UK and Spain, mutations in a single microRNA were just reported to cause deafness in humans and mice, showing the importance of microRNAs in the inner ear.

"We've found that 'hair' cell microRNAs are regulators involved
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Emergence of recombinant forms of HIV: dynamics and scaling
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scaling the wall of deafness
(Date:3/31/2015)... NEW YORK , March 31, 2015  Elephant ... the "Company"), a global provider of Software Defined Network ... solutions, today announced total revenue of approximately $20.4 million ... to a restated $19.5 million for the year ended ... of calendar 2014, the Company had completed its multi-year ...
(Date:3/24/2015)... , Mar. 24, 2015 Research and Markets ... and Voice Biometrics - Global Strategic Business Report" report to ... Face and Voice Biometrics in US$ Thousands by the following Segments: ... for the US, Canada , Japan ... , Middle East & Africa ...
(Date:3/23/2015)...  In the 2014 fiscal year, irs.gov recorded over ... figure accounts for a fraction of the estimated losses ... exceeds $11 billion globally. The polygraph has traditionally been ... occurred. Investor Mark Saint Juste along with ... partnered to administer the test in a new ...
Breaking Biology News(10 mins):Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3
... estimate sources and losses of organic carbon in surface waters ... as both sources and sinks for organic carbon. ... streams, which is information that is ultimately needed to improve ... in the atmosphere," said Dr. Richard Smith, a USGS hydrologist ...
... themselves from most bacteria, but some bacteria are able to ... Science on Friday, scientists have identified the genes used ... overwhelm defensive natural products produced by plants of the mustard ... find a way to infect a host and overwhelm the ...
... is a labor-intensive part of commercial peach and nectarine ... been shown to reduce labor requirements and improve fruit ... needed more information about the range of thinning times. ... The Pennsylvania State University and Penn State Cooperative Extension ...
Cached Biology News:What is good for you is bad for infectious bacteria 2String blossom thinner proves effective across stages of bloom development 2
(Date:4/17/2015)... , April 17, 2015 /PRNewswire/ - SQI Diagnostics ... and diagnostics company that develops and commercializes proprietary ... today announced that it has received approval from ... of 5,126,044 outstanding common share purchase warrants ("the ... connection with the Company,s May 2013 private placement ...
(Date:4/17/2015)... , April 17, 2015  US-Australian drug discovery ... a Memorandum of Understanding with the Feinstein Institute ... New York to collaborate with the ... The collaboration brings together the drug ... clinical expertise of the Feinstein Institute in neurosciences ...
(Date:4/17/2015)... LC Sciences LLC, a leading developer ... it is seeking beta testers for the VariantProâ„¢ ... targeted sequencing technology. The system offers cost-effective, minimal ... detection of rare variants. It utilizes novel and ... will collaborate with beta testers to generate test ...
(Date:4/16/2015)... 17, 2015 Spirax Sarco, the ... released their newly designed, state-of-the-art website in the ... website effectively promotes the Spirax Sarco brand, company ... information that a site visitor might be looking ... capabilities, industries serviced, the latest company news, careers, ...
Breaking Biology Technology:SQI Diagnostics to Extend Warrant Expiry 2SQI Diagnostics to Extend Warrant Expiry 3Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 2Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 3Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 4Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 5Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 6LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 2LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 3Spirax Sarco website has a new look 2
... Mass., Aug. 17 Indevus,Pharmaceuticals, Inc. (Nasdaq: ... approvable letter from the U.S. Food and Drug ... valrubicin for intravesical,instillation, is the only product approved ... carcinoma in situ (CIS) of the,urinary bladder. ...
... announced today they,have entered into a five-year agreement ... Region 3 to provide RealTime1(TM) (RT1(TM)),software at 15 ... the,US Virgin Islands. The Region 3 Genetics Collaborative, ... for another five-year period.,With this renewal, Region 3 ...
... Inc. (Nasdaq: EMIS ) announced today that it ... common stock and warrants to,purchase 0.4 million shares of ... The five-year warrants will be exercisable at any time ... price of $3.948 per share. The securities in ...
Cached Biology Technology:Indevus Receives Approvable Letter From FDA for VALSTAR(R) for Bladder Cancer Therapy 2Indevus Receives Approvable Letter From FDA for VALSTAR(R) for Bladder Cancer Therapy 3Indevus Receives Approvable Letter From FDA for VALSTAR(R) for Bladder Cancer Therapy 4Digital Union's RT1(TM) Software Creates Telegenetics Network for Region 3 Genetics Collaborative 2Emisphere Technologies, Inc. Announces Pricing of Registered Direct Offering 2
... dotLab System brings together two mature, ... immobilized capture surfaces. This combination produces ... for the detection of molecular binding ... labels. , Protein-specific capture molecules are ...
... 5'G AATTC3' 3'CTTAA G5' Inactivation Conditions: Heat inactivation ... Storage Conditions: 10mM Tris-HCl (pH 7.5), 100mM KCl, ... BSA, 50% glycerol. Shipping and Storage: Shipped on ... unit is defined as the amount of enzyme ...
The HEPTEST assays provide a sensitive, simple, rapid, and convenient in vitro quantitation of heparin, low molecular weight heparins, and heparinoids in plasma and whole blood. Sample Type: wh...
... a comprehensive experiment based analysis package designed ... yet sophisticated and powerful functionality., Image acquisition ... cameras for easy image capture. Sequential ... Video Playback Saturation Warning ...
Biology Products: