Navigation Links
Scale models
Date:8/22/2011

ical model back into the lab, carrying out experiments on fruit fly larvae, in which wing patterning already begins in small structures called wing discs.

The scientists collected fruit fly larvae of varying sizes and, using a quantitative method they developed, checked the distribution of concentrations of a morphogen called Dpp. Then, they eliminated another molecule called Pentagone which they suspected of playing the role of expander from the developing wing disc and checked again. Their findings showed that the wings in the unaltered fruit flies revealed the morphogen scaling activity predicted by the model, its signals being proportionate to wing size. In contrast, in the flies without Pentagone the Dpp morphogen was distributed in the same way in all the wings, regardless of their relative sizes. Thus, they were able to show that Pentagone is, indeed, an expansion molecule and that the expansion-repression paradigm they had formulated can be applied to such differing organisms as frogs and fruit flies.

Shilo: 'The beauty of this research lies in the way it seamlessly weaves a theoretical model into experimental biology. With this fresh, new approach to investigating scaling, rather than searching for complex molecular mechanisms, we can begin by looking for this relatively simple and universal paradigm.'


'/>"/>

Contact: Batya Greenman
news@weizmann.ac.il
972-893-43856
Weizmann Institute of Science
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers find way to align gold nanorods on a large scale
2. 1st large-scale map of a plants protein network addresses evolution, disease process
3. Study shows small-scale fisheries impact on marine life
4. New technique yields troves of information from nanoscale bone samples
5. Patent for arrays of nanoscale electrical probes awarded to NJIT today
6. Mimicking nature at the nanoscale: Selective transport across a biomimetic nanopore
7. Pesticide impact: Comparing lab, field-scale results
8. Penn researchers help nanoscale engineers choose self-assembling proteins
9. New nanoscale imaging may lead to new treatments for multiple sclerosis
10. Atomic-scale structures of ribosome could help improve antibiotics
11. Study Shows Sutro Biopharmas Biochemical Protein Synthesis Technology Enables Rapid Production and Scale-Up of Biopharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... NY - July 24, 2014 -- Keryx Biopharmaceuticals, Inc. ... the long-term, randomized, active control Phase 3 study of ... phosphate binder, for the treatment of hyperphosphatemia in patients ... study (PhosphatE binding and iRon delivery with FErric CiTrate ... Journal of the American Society of Nephrology ( ...
(Date:7/24/2014)... on different species of fish, according to a ... Exeter which tested fish anti-predator behaviour. , ... predator model when exposed to additional noise, whereas ... , Lead author Dr Irene Voellmy of Bristol,s ... many aquatic environments have increased substantially during the ...
(Date:7/24/2014)... its own microbial terroir, meaning the microbial populations found ... the product, creating the final flavor according to research ... and Environmental Microbiology . This is the first time ... brewery. , Many sake makers inoculate with both ... of the University of California, Davis, but he and ...
Breaking Biology News(10 mins):Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 2Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 3Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 4The microbes make the sake brewery 2
... Researchers at Oregon State University have helped sequence ... for genetic improvements to related fruits like apples, peaches ... the journal Nature Genetics . "This will ... commercial strawberries," said OSU plant molecular biologist Todd Mockler, ...
... international research consortium has sequenced the genome of the ... Dec. 26 advance online edition of the journal ... possibilities for breeding tastier, hardier varieties of the berry ... the strawberry parts list," said the consortium,s leader Kevin ...
... brain tumours in larvae of the fruit fly Drosophila ... grow. The removal of some of these genes leads to ... for tumour development. The study, headed by ICREA researcher Cayetano ... . One of the characteristics of tumour cells ...
Cached Biology News:OSU helps decode strawberry genome in bid to improve fruit 2OSU helps decode strawberry genome in bid to improve fruit 3Georgia Tech team helps decode newly sequenced strawberry genome 2Georgia Tech team helps decode newly sequenced strawberry genome 3Some brain tumors mimic the genetic program of germline cells 2
(Date:7/24/2014)... , July 24, 2014 SRI International has ... the National Institute of Allergy and Infectious Diseases (NIAID), ... preclinical development of potential therapies for HIV infection and ... treat HIV and AIDS and the complications and opportunistic ... for preventing sexual transmission of HIV. ...
(Date:7/24/2014)... 2014 WIRB-Copernicus Group ® ("WCG")™, ... review services for clinical research, announced today that ... of Richmond, VA -based Alliance ... biosecurity consulting firm in the United ... division – WCG Biosafety™ – will be able ...
(Date:7/24/2014)... 2014   Cypher Genomics, Inc., the ... Adam Simpson as president and chief ... comprehensive annotation and interpretation of individual human genomes ... "Cypher,s technology has the potential to play a ... accuracy, optimizing therapeutic approaches and reducing adverse drug ...
(Date:7/23/2014)... BioSciences, Inc. (NASDAQ: SGMO ) today reported ... For the second quarter ended June 30, ... million, or $0.10 per share, compared to a net ... the same period in 2013. As of June 30, ... and interest receivable of $236.7 million. Revenues ...
Breaking Biology Technology:National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 3Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 2Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 3Sangamo BioSciences Reports Second Quarter 2014 Financial Results 2Sangamo BioSciences Reports Second Quarter 2014 Financial Results 3Sangamo BioSciences Reports Second Quarter 2014 Financial Results 4Sangamo BioSciences Reports Second Quarter 2014 Financial Results 5Sangamo BioSciences Reports Second Quarter 2014 Financial Results 6Sangamo BioSciences Reports Second Quarter 2014 Financial Results 7Sangamo BioSciences Reports Second Quarter 2014 Financial Results 8Sangamo BioSciences Reports Second Quarter 2014 Financial Results 9
... Oct. 20 Prometheus Research LLC has formed the ... including dashboards and reports. The group will draw on ... of building custom biomedical data management applications. ... said Andrzej Pienczykowski, Executive Vice President for Product Development ...
... Incorporated (NYSE: DGX ), the world,s leading ... its Board of Directors increased the company,s share repurchase ... first three quarters of 2010, the company repurchased approximately ... fully utilizing its previous authorization, which was granted in ...
... OAK RIDGE, Tenn., Oct. 19, 2010 -- The Cold ... National Laboratory,s High Flux Isotope Reactor and a complementary ... entered its commissioning phase. The CTAX uses "cold" ... magnetic excitations in materials. Cold neutrons are slower than ...
Cached Biology Technology:Prometheus Research Launches Solutions Group to Springboard HTSQL-based Solutions for Customers 2ORNL's research reactor revamps veteran neutron scattering tool 2
dithiothreitol (DTT) Reactive Dyes and Chemicals Thiol-Reactive Dyes, Haptens and Quenchers Reducing Agents...
GRADIENT MAKER, 30 ML, 1 EA. Category: Protein Vertical Instruments....
Recombinant Rat Leptin, CF...
actin from rabbit muscle Cell Biology Cytoskeletal Probes Actin and Actin Probes...
Biology Products: