Navigation Links
Scaffold gradients: Finding the right environment for developing cells
Date:5/27/2010

People often have strong opinions on the "right" firmness of mattresses for themselves, and, as it turns out, some cell types have similar preferences for their support structures. Now a research team from the National Institute of Standards and Technology (NIST) and the National Institutes of Health (NIH) has developed a way to offer cells a three-dimensional scaffold that varies over a broad range of degrees of stiffness to determine where they develop best. Their recently published technique* is a way to rapidly optimize 3D cell growth media to meet the developmental needs of specific cell types for a wide variety of potential tissue-replacement therapies.

Tissue engineering is a relatively new field that is developing methods to grow or regenerate bodily tissuesskin, bone, cartilage, blood vessels, perhaps one day even whole organsto replace those damaged by injury or disease. One of the key challenges in the field is developing appropriate three-dimensional "scaffolds," artificial materials that can hold tissue progenitor cells and allow them to be nurtured and supported while they multiply and develop into desired tissues. Research has shown that cells often need to develop in a 3D environment if they are to mature and differentiate properly.

Hydrogelsmost familiar for their use in soft contact lensesare a promising material for tissue scaffolds. They consist of a loose network of polymer chains that is swollen with water; in fact, like the majority of the body's tissues, they are mostly water.

But, says NIST materials scientist Kaushik Chatterjee, deciding on a hydrogel is just the beginning. "Now you've got these gels, what sort of properties do you want? What gets you the best kind of whatever tissue you're afterin our case, bone? We focused on stiffness because cells are known to sense and respond to changes in the stiffness of their environment."

To test this, the research team developed a method to create sam
'/>"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Smart orthopedic implants and self-fitting tissue scaffolding created by UMMS researchers
2. MDC researchers identify a scaffold regulating protein disposal
3. Spaghetti scaffolding could help grow skin in labs
4. Non-wovens as scaffolds for artificial tissue
5. MIT: New tissue scaffold regrows cartilage and bone
6. Smart scaffolds may help heal broken hearts
7. Hydrogels provide scaffolding for growth of bone cells
8. Scientists discover a molecular scaffold that guides connections between brain cells
9. Can micro-scaffolding help stem cells rebuild the brain after stroke?
10. Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
11. Finding the soft spot
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scaffold gradients: Finding the right environment for developing cells
(Date:8/24/2015)... TOWN, South Africa , August 24, 2015 ... Germany ,s largest biometrics manufacturer DERMALOG and ... with the "2015 African Biometrics Company of the Year ... in Nigeria .   -Cross ... and http://www.presseportal.de/nr/8896 - On Thursday evening, ...
(Date:8/20/2015)... , Aug. 20, 2015   Sensory, ... on improving the user experience and security of ... technologies, today announced that its TrulySecure™ ... authentication software to be FIDO Certified™. ... for compliance with the FIDO UAF (Universal Authentication ...
(Date:8/18/2015)... 2015  Navitas today announced that it ... Submission Content Management webinar scheduled on August ... to the Implementation of Regulatory Submission Standards ... industry, vendors, health authorities, consultants and the ... a standard method of implementing electronic submission ...
Breaking Biology News(10 mins):Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 2Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3
... CAMBRIDGE, Mass. -- Clinical trials using patients, own immune cells ... usually works only if the patients also receive large doses ... those drugs have life-threatening side effects. Now a team ... necessary drugs by smuggling them on the backs of the ...
... Researchers at North Carolina State University have developed ... with biological systems including the human body. Their ... environmental safety in the handling of nanomaterials, as well ... Dr. Jim Riviere, Burroughs Wellcome Distinguished Professor of ...
... July 26 Aware, Inc. (Nasdaq: www.aware.com/ir . ... 719-457-2621 and referencing the confirmation number 5684541.  A replay ... after the call. About Aware ... for the telecommunications and biometrics industries. Aware has pioneered ...
Cached Biology News:Drugs encased in nanoparticles travel to tumors on the surface of immune-system cells 2Drugs encased in nanoparticles travel to tumors on the surface of immune-system cells 3Probing the nanoparticle: Predicting how nanoparticles will react in the human body 2Aware, Inc. Reports Second Quarter 2010 Financial Results 2Aware, Inc. Reports Second Quarter 2010 Financial Results 3Aware, Inc. Reports Second Quarter 2010 Financial Results 4Aware, Inc. Reports Second Quarter 2010 Financial Results 5Aware, Inc. Reports Second Quarter 2010 Financial Results 6Aware, Inc. Reports Second Quarter 2010 Financial Results 7Aware, Inc. Reports Second Quarter 2010 Financial Results 8Aware, Inc. Reports Second Quarter 2010 Financial Results 9Aware, Inc. Reports Second Quarter 2010 Financial Results 10Aware, Inc. Reports Second Quarter 2010 Financial Results 11Aware, Inc. Reports Second Quarter 2010 Financial Results 12Aware, Inc. Reports Second Quarter 2010 Financial Results 13Aware, Inc. Reports Second Quarter 2010 Financial Results 14Aware, Inc. Reports Second Quarter 2010 Financial Results 15Aware, Inc. Reports Second Quarter 2010 Financial Results 16Aware, Inc. Reports Second Quarter 2010 Financial Results 17Aware, Inc. Reports Second Quarter 2010 Financial Results 18Aware, Inc. Reports Second Quarter 2010 Financial Results 19Aware, Inc. Reports Second Quarter 2010 Financial Results 20Aware, Inc. Reports Second Quarter 2010 Financial Results 21Aware, Inc. Reports Second Quarter 2010 Financial Results 22
(Date:8/27/2015)... , Aug. 27, 2015  Asterias Biotherapeutics, Inc. (NYSE ... field of regenerative medicine, today announced that executives from ... the month of September.  , ... Rodman & Renshaw,s 17th Annual Global Investment Conference on ... the St. Regis Hotel in New York ...
(Date:8/27/2015)... -- HUYA Bioscience International (HUYA) today announced the sponsorship of ... HTLV-1, held this week at the University of Tokyo ... is to promote research on HTLV-1 and HTLV-1-associated diseases, ... research related to these fields to advance science, the ... to support this prestigious conference," said Mireille Gillings ...
(Date:8/27/2015)... ... August 27, 2015 , ... Inc. Magazine released its annual ... Solutions as number 1,361 in growth for the three years through 2014. Being named ... fastest-growing privately held organizations in the country. , “We are thrilled to make ...
(Date:8/27/2015)... Aug. 27, 2015 In response to ... UPS and The US Postal Service to no ... as ,select agents, by the CDC, Marken reaffirmed ... these sensitive shipments. Marken uses its ... trained and certified personnel to ensure the safe ...
Breaking Biology Technology:Asterias Biotherapeutics to Present at Upcoming Investor Conferences 2HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 2HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 3HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 4iLab Solutions Named to 2015 Inc. 5000 List 2iLab Solutions Named to 2015 Inc. 5000 List 3Marken Ensures Safe Transportation Of Select Agents And Toxins 2
... PharmSource Lead Sheet upgrades database resources to help companies serving ... , ... Springfield, VA (PRWEB) November ... Information Services, Inc. (PharmSource) announces the expansion of its PharmSource ...
... quantum computing is that it will dramatically outshine traditional ... factoring large numbers, creating uncrackable codes and simulating the ... that direction, if you,ll pardon the pun, has been ... a paper published in the journal Nature . ...
... ARBOR, Mich., Nov. 21 MichBio, the association ... service providers to its fourth annual Expo on ... Financial ShowPlace in Novi, MI. The MichBio ... industry professionals.,In addition, this year,s event attracted 56 ...
Cached Biology Technology:PharmSource Introduces Proprietary Resource for Identifying New Business Opportunities in Bio/Pharma 2Stanford: Quantum computing spins closer 2MichBio Expo Draws Nearly 500 Professionals; Career Day Raises Profile 2MichBio Expo Draws Nearly 500 Professionals; Career Day Raises Profile 3
... Cell Transformation Detection Assay is an anchorage-independent ... considered the most stringent assay for detecting ... assay, cells (pre-treated with carcinogens or carcinogen ... soft agar medium for 21-28 days. ...
The Saturn 2200 answers your GC/MS questions with the CP-3800 GC and the 2000 Series Ion Trap MS! These components create a platform for the worlds most versatile GC and flexible MS. Both deliver une...
... EZ DNA Methylation Kit uses a simplified ... DNA methylation analysis. The kit is based ... place between cytosine and sodium bisulfite where ... DNA Methylation Kits innovative in-column desulphonation reaction ...
... Gels easier and more efficient by providing ... types of pre-cut pre-assembled membrane/filter paper sandwiches ... cm E-PAGE Gels*. The available nitrocellulose and ... transfer of proteins (Figure 1 Table 1). ...
Biology Products: